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insights for Homo sapiens (human), Cynomolgus monkeys, rodents
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Target
sublocation: Introcelluar Protein.
This gene encodes a basic helix-loop-helix domain-containing transcription factor that binds MUE3-type E-box sequences in the promoter of genes. The encoded protein promotes the expression of genes downstream of transforming growth factor beta (TGF-beta) signaling. This gene may be involved in chromosomal translocations in renal cell carcinomas and other cancers, resulting in the production of fusion proteins. Translocation partners include PRCC (papillary renal cell carcinoma), NONO (non-POU domain containing, octamer-binding), and ASPSCR1 (alveolar soft part sarcoma chromosome region, candidate 1), among other genes. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013]
| Target ID |
GM-IP11682
|
| Target Name |
TFE3
|
Gene Group ldentifer (Target Gene ID in Homo
species)
|
7030
|
| Gene ID |
100051983 (Equus caballus), 101099025 (Felis catus), 209446 (Mus musculus), 317376 (Rattus norvegicus) 491872 (Canis lupus familiaris), 520800 (Bos taurus), 7030 (Homo sapiens), 712161 (Macaca mulatta)
|
| Target Alternative Names |
Class E basic helix-loop-helix protein 33 (bHLHe33),F830016E06Rik,MRXSPF,RCCP2,RCCX1,RGD1559642,TFE3,TFEA,Tcfe3,Tfe-3,Tfe3,Transcription factor E3,bHLHe33,mTFE3
|
| Uniprot Accession |
Q64092,Q05B92,P19532
|
| Protein Sub-location |
Introcelluar Protein
|
| Category |
Life Science Target
|
| Disease |
cancer, Prostate Cancer
|
| Gene Ensembl |
ENSECAG00000020642, ENSMUSG00000000134, ENSCAFG00845031022, ENSBTAG00000008523, ENSG00000068323, ENSMMUG00000023494
|
Pre-made viral vector of TFE3 cDNA Clones/ORF Plasmid
TFE3 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo7030 | Pre-made Human TFE3/TFEA/RCCP2 siRNA oligo Duplex | 7030 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo317376 | Pre-made Rat Tfe3/Tcfe3/RGD1559642 siRNA oligo Duplex | 317376 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo209446 | Pre-made Mouse Tfe3/Tcfe3/Tfe-3 siRNA oligo Duplex | 209446 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo712161 | Pre-made Cynomolgus/Rhesus macaque TFE3 siRNA oligo Duplex | 712161 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101099025 | Pre-made Cat/Feline TFE3 siRNA oligo Duplex | 101099025 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo491872 | Pre-made Dog/Canine TFE3 siRNA oligo Duplex | 491872 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo520800 | Pre-made Bovines/Cattle TFE3 siRNA oligo Duplex | 520800 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100051983 | Pre-made Equine/Horse TFE3 siRNA oligo Duplex | 100051983 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
TFE3 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-IP11682-Ab | Human | Anti-Human TFE3 monoclonal antibody | mab | | Detail |
| GM-Tg-rg-IP11682-Ab | Rat | Anti-Rat TFE3 monoclonal antibody | mab | | Detail |
| GM-Tg-mg-IP11682-Ab | Mouse | Anti-Mouse TFE3 monoclonal antibody | mab | | Detail |
| GM-Tg-cynog-IP11682-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque TFE3 monoclonal antibody | mab | | Detail |
| GM-Tg-felg-IP11682-Ab | Cat/Feline | Anti-Cat/Feline TFE3 monoclonal antibody | mab | | Detail |
| GM-Tg-cang-IP11682-Ab | Dog/Canine | Anti-Dog/Canine TFE3 monoclonal antibody | mab | | Detail |
| GM-Tg-bovg-IP11682-Ab | Bovines/Cattle | Anti-Bovines/Cattle TFE3 monoclonal antibody | mab | | Detail |
| GM-Tg-equg-IP11682-Ab | Equine/Horse | Anti-Equine/Horse TFE3 monoclonal antibody | mab | | Detail |
TFE3 recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-IP11682-Ag | Human | Human TFE3 recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-IP11682-Ag | Rat | Rat TFE3 recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-IP11682-Ag | Mouse | Mouse TFE3 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-IP11682-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque TFE3 recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-IP11682-Ag | Cat/Feline | Cat/Feline TFE3 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-IP11682-Ag | Dog/Canine | Dog/Canine TFE3 recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-IP11682-Ag | Bovines/Cattle | Bovines/Cattle TFE3 recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-IP11682-Ag | Equine/Horse | Equine/Horse TFE3 recombinant protein | Mammalian cell | Detail |