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Target
sublocation: Introcelluar Protein.
This gene encodes a member of the T-cell factor/lymphoid enhancer-binding factor family of high mobility group (HMG) box transcriptional activators. This gene is expressed predominantly in T-cells and plays a critical role in natural killer cell and innate lymphoid cell development. The encoded protein forms a complex with beta-catenin and activates transcription through a Wnt/beta-catenin signaling pathway. Mice with a knockout of this gene are viable and fertile, but display a block in T-lymphocyte differentiation. Alternative splicing results in multiple transcript variants. Naturally-occurring isoforms lacking the N-terminal beta-catenin interaction domain may act as dominant negative regulators of Wnt signaling. [provided by RefSeq, Oct 2016]
| Target ID |
GM-IP11644
|
| Target Name |
TCF1/TCF7
|
Gene Group ldentifer (Target Gene ID in Homo
species)
|
6932
|
| Gene ID |
100072786 (Equus caballus), 101098768 (Felis catus), 21414 (Mus musculus), 363595 (Rattus norvegicus) 481506 (Canis lupus familiaris), 6932 (Homo sapiens), 710234 (Macaca mulatta), 782690 (Bos taurus)
|
| Target Alternative Names |
T-cell-specific transcription factor 1 (T-cell factor 1,TCF-1,TCF-1),TCF-7,TCF1,TCF7,Tcf1,Tcf7,Transcription factor 7
|
| Uniprot Accession |
Q00417,P36402
|
| Protein Sub-location |
Introcelluar Protein
|
| Category |
Life Science Target
|
| Disease |
cancer
|
| Gene Ensembl |
ENSECAG00000008098, ENSMUSG00000000782, ENSG00000081059, ENSMMUG00000022788, ENSBTAG00000001002
|
Pre-made viral vector of TCF1/TCF7 cDNA Clones/ORF Plasmid
TCF1/TCF7 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo6932 | Pre-made Human TCF7/TCF-1 siRNA oligo Duplex | 6932 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo363595 | Pre-made Rat Tcf7 siRNA oligo Duplex | 363595 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo21414 | Pre-made Mouse Tcf7/Tcf1/TCF-1 siRNA oligo Duplex | 21414 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo710234 | Pre-made Cynomolgus/Rhesus macaque TCF7 siRNA oligo Duplex | 710234 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101098768 | Pre-made Cat/Feline TCF7 siRNA oligo Duplex | 101098768 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo481506 | Pre-made Dog/Canine TCF7 siRNA oligo Duplex | 481506 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo782690 | Pre-made Bovines/Cattle TCF7 siRNA oligo Duplex | 782690 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100072786 | Pre-made Equine/Horse TCF7 siRNA oligo Duplex | 100072786 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
TCF1/TCF7 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-IP11644-Ab | Human | Anti-Human TCF1/TCF7 monoclonal antibody | mab | | Detail |
| GM-Tg-rg-IP11644-Ab | Rat | Anti-Rat TCF1/TCF7 monoclonal antibody | mab | | Detail |
| GM-Tg-mg-IP11644-Ab | Mouse | Anti-Mouse TCF1/TCF7 monoclonal antibody | mab | | Detail |
| GM-Tg-cynog-IP11644-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque TCF1/TCF7 monoclonal antibody | mab | | Detail |
| GM-Tg-felg-IP11644-Ab | Cat/Feline | Anti-Cat/Feline TCF1/TCF7 monoclonal antibody | mab | | Detail |
| GM-Tg-cang-IP11644-Ab | Dog/Canine | Anti-Dog/Canine TCF1/TCF7 monoclonal antibody | mab | | Detail |
| GM-Tg-bovg-IP11644-Ab | Bovines/Cattle | Anti-Bovines/Cattle TCF1/TCF7 monoclonal antibody | mab | | Detail |
| GM-Tg-equg-IP11644-Ab | Equine/Horse | Anti-Equine/Horse TCF1/TCF7 monoclonal antibody | mab | | Detail |
TCF1/TCF7 recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-IP11644-Ag | Human | Human TCF1/TCF7 recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-IP11644-Ag | Rat | Rat TCF1/TCF7 recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-IP11644-Ag | Mouse | Mouse TCF1/TCF7 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-IP11644-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque TCF1/TCF7 recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-IP11644-Ag | Cat/Feline | Cat/Feline TCF1/TCF7 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-IP11644-Ag | Dog/Canine | Dog/Canine TCF1/TCF7 recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-IP11644-Ag | Bovines/Cattle | Bovines/Cattle TCF1/TCF7 recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-IP11644-Ag | Equine/Horse | Equine/Horse TCF1/TCF7 recombinant protein | Mammalian cell | Detail |