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Target
sublocation: Introcelluar Protein.
This gene is a member of the small GTPase superfamily and encodes a lipid-anchored, cell membrane protein with five repeats of the RAS-related GTP-binding region. This protein is vital in regulation of growth and cell cycle progression due to its role in the insulin/TOR/S6K signaling pathway. The protein has GTPase activity and shuttles between a GDP-bound form and a GTP-bound form, and farnesylation of the protein is required for this activity. Three pseudogenes have been mapped, two on chromosome 10 and one on chromosome 22. [provided by RefSeq, Jul 2008]
| Target ID |
GM-IP10906
|
| Target Name |
RHEB
|
Gene Group ldentifer (Target Gene ID in Homo
species)
|
6009
|
| Gene ID |
100064440 (Equus caballus), 101083160 (Felis catus), 19744 (Mus musculus), 26954 (Rattus norvegicus) 475545 (Canis lupus familiaris), 528204 (Bos taurus), 6009 (Homo sapiens), 715378 (Macaca mulatta)
|
| Target Alternative Names |
GTP-binding protein Rheb,RHEB,RHEB2,Ras homolog enriched in brain,Rheb,Rheb1
|
| Uniprot Accession |
Q921J2,Q62639,Q56JV3,Q15382
|
| Protein Sub-location |
Introcelluar Protein
|
| Category |
Life Science Target
|
| Disease |
cancer
|
| Gene Ensembl |
ENSECAG00000008243, ENSMUSG00000028945, ENSCAFG00845011138, ENSBTAG00000031861, ENSG00000106615, ENSMMUG00000051076
|
Pre-made viral vector of RHEB cDNA Clones/ORF Plasmid
RHEB siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo6009 | Pre-made Human RHEB/RHEB2 siRNA oligo Duplex | 6009 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo26954 | Pre-made Rat Rheb siRNA oligo Duplex | 26954 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo19744 | Pre-made Mouse Rheb/Rheb1 siRNA oligo Duplex | 19744 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo715378 | Pre-made Cynomolgus/Rhesus macaque RHEB siRNA oligo Duplex | 715378 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101083160 | Pre-made Cat/Feline RHEB siRNA oligo Duplex | 101083160 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo475545 | Pre-made Dog/Canine RHEB siRNA oligo Duplex | 475545 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo528204 | Pre-made Bovines/Cattle RHEB siRNA oligo Duplex | 528204 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100064440 | Pre-made Equine/Horse RHEB siRNA oligo Duplex | 100064440 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
RHEB antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-IP10906-Ab | Human | Anti-Human RHEB monoclonal antibody | mab | | Detail |
| GM-Tg-rg-IP10906-Ab | Rat | Anti-Rat RHEB monoclonal antibody | mab | | Detail |
| GM-Tg-mg-IP10906-Ab | Mouse | Anti-Mouse RHEB monoclonal antibody | mab | | Detail |
| GM-Tg-cynog-IP10906-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque RHEB monoclonal antibody | mab | | Detail |
| GM-Tg-felg-IP10906-Ab | Cat/Feline | Anti-Cat/Feline RHEB monoclonal antibody | mab | | Detail |
| GM-Tg-cang-IP10906-Ab | Dog/Canine | Anti-Dog/Canine RHEB monoclonal antibody | mab | | Detail |
| GM-Tg-bovg-IP10906-Ab | Bovines/Cattle | Anti-Bovines/Cattle RHEB monoclonal antibody | mab | | Detail |
| GM-Tg-equg-IP10906-Ab | Equine/Horse | Anti-Equine/Horse RHEB monoclonal antibody | mab | | Detail |
RHEB recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-IP10906-Ag | Human | Human RHEB recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-IP10906-Ag | Rat | Rat RHEB recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-IP10906-Ag | Mouse | Mouse RHEB recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-IP10906-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque RHEB recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-IP10906-Ag | Cat/Feline | Cat/Feline RHEB recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-IP10906-Ag | Dog/Canine | Dog/Canine RHEB recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-IP10906-Ag | Bovines/Cattle | Bovines/Cattle RHEB recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-IP10906-Ag | Equine/Horse | Equine/Horse RHEB recombinant protein | Mammalian cell | Detail |