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insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Introcelluar Protein.
This gene was initially identified as a transcriptional repressor that represses neuronal genes in non-neuronal tissues. However, depending on the cellular context, this gene can act as either an oncogene or a tumor suppressor. The encoded protein is a member of the Kruppel-type zinc finger transcription factor family. It represses transcription by binding a DNA sequence element called the neuron-restrictive silencer element. The protein is also found in undifferentiated neuronal progenitor cells and it is thought that this repressor may act as a master negative regulator of neurogenesis. Alternatively spliced transcript variants have been described. [provided by RefSeq, May 2018]
| Target ID |
GM-IP10889
|
| Target Name |
REST
|
Gene Group ldentifer (Target Gene ID in Homo
species)
|
5978
|
| Gene ID |
100058152 (Equus caballus), 100425257 (Macaca mulatta), 101086719 (Felis catus), 19712 (Mus musculus) 482163 (Canis lupus familiaris), 507148 (Bos taurus), 5978 (Homo sapiens), 83618 (Rattus norvegicus)
|
| Target Alternative Names |
2610008J04Rik,DFNA27,GINGF5,HGF5,NRSF,Neural-restrictive silencer factor,Nrsf,RE1-silencing transcription factor,REST,REST4,RESTB,Rest,WT6,X2 box repressor,XBR
|
| Uniprot Accession |
Q8VIG1,Q13127,O54963
|
| Protein Sub-location |
Introcelluar Protein
|
| Category |
Life Science Target
|
| Disease |
cancer
|
| Gene Ensembl |
ENSECAG00000022536, ENSMMUG00000018821, ENSMUSG00000029249, ENSCAFG00845013968, ENSBTAG00000011789, ENSG00000084093
|
Pre-made viral vector of REST cDNA Clones/ORF Plasmid
REST siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo5978 | Pre-made Human REST/WT6/XBR siRNA oligo Duplex | 5978 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo83618 | Pre-made Rat Rest/Nrsf siRNA oligo Duplex | 83618 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo19712 | Pre-made Mouse Rest/NRSF/REST4 siRNA oligo Duplex | 19712 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100425257 | Pre-made Cynomolgus/Rhesus macaque REST siRNA oligo Duplex | 100425257 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101086719 | Pre-made Cat/Feline REST siRNA oligo Duplex | 101086719 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo482163 | Pre-made Dog/Canine REST siRNA oligo Duplex | 482163 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo507148 | Pre-made Bovines/Cattle RESTB/REST siRNA oligo Duplex | 507148 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100058152 | Pre-made Equine/Horse REST siRNA oligo Duplex | 100058152 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
REST antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-IP10889-Ab | Human | Anti-Human REST monoclonal antibody | mab | | Detail |
| GM-Tg-rg-IP10889-Ab | Rat | Anti-Rat REST monoclonal antibody | mab | | Detail |
| GM-Tg-mg-IP10889-Ab | Mouse | Anti-Mouse REST monoclonal antibody | mab | | Detail |
| GM-Tg-cynog-IP10889-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque REST monoclonal antibody | mab | | Detail |
| GM-Tg-felg-IP10889-Ab | Cat/Feline | Anti-Cat/Feline REST monoclonal antibody | mab | | Detail |
| GM-Tg-cang-IP10889-Ab | Dog/Canine | Anti-Dog/Canine REST monoclonal antibody | mab | | Detail |
| GM-Tg-bovg-IP10889-Ab | Bovines/Cattle | Anti-Bovines/Cattle REST monoclonal antibody | mab | | Detail |
| GM-Tg-equg-IP10889-Ab | Equine/Horse | Anti-Equine/Horse REST monoclonal antibody | mab | | Detail |
REST recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-IP10889-Ag | Human | Human REST recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-IP10889-Ag | Rat | Rat REST recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-IP10889-Ag | Mouse | Mouse REST recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-IP10889-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque REST recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-IP10889-Ag | Cat/Feline | Cat/Feline REST recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-IP10889-Ag | Dog/Canine | Dog/Canine REST recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-IP10889-Ag | Bovines/Cattle | Bovines/Cattle REST recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-IP10889-Ag | Equine/Horse | Equine/Horse REST recombinant protein | Mammalian cell | Detail |