Explore BCKDHA gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
premier destination for multi-species gene research solutions
Target
sublocation: Introcelluar Protein.
The branched-chain alpha-keto acid (BCAA) dehydrogenase (BCKD) complex is an innter mitochondrial enzyme complex that catalyzes the second major step in the catabolism of the branched-chain amino acids leucine, isoleucine, and valine. The BCKD complex consists of three catalytic components: a heterotetrameric (alpha2-beta2) branched-chain alpha-keto acid decarboxylase (E1), a dihydrolipoyl transacylase (E2), and a dihydrolipoamide dehydrogenase (E3). This gene encodes the alpha subunit of the decarboxylase (E1) component. Mutations in this gene result in maple syrup urine disease, type IA. Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Sep 2009]
| Target ID |
GM-IP10864
|
| Target Name |
BCKDHA
|
Gene Group ldentifer (Target Gene ID in Homo
species)
|
593
|
| Gene ID |
100068678 (Equus caballus), 101087186 (Felis catus), 106994773 (Macaca mulatta), 12039 (Mus musculus) 25244 (Rattus norvegicus), 282149 (Bos taurus), 484488 (Canis lupus familiaris), 593 (Homo sapiens)
|
| Target Alternative Names |
2-oxoisovalerate dehydrogenase subunit alpha,BCKAD,BCKDA,BCKDE1A,BCKDH E1-alpha),BCKDHA,Bckdha,Branched-chain alpha-keto acid dehydrogenase E1 component alpha chain (BCKDE1A,E1[a],E1a,MSU,MSUD1,MSUD1A,OVD1A,mitochondrial
|
| Uniprot Accession |
P50136,P11960,P11178,P12694
|
| Protein Sub-location |
Introcelluar Protein
|
| Category |
Life Science Target
|
| Gene Ensembl |
ENSECAG00000012246, ENSMMUG00000014346, ENSMUSG00000060376, ENSBTAG00000016037, ENSCAFG00845002258, ENSG00000248098
|
Pre-made viral vector of BCKDHA cDNA Clones/ORF Plasmid
BCKDHA siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo593 | Pre-made Human BCKDHA/MSU/MSUD1 siRNA oligo Duplex | 593 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo25244 | Pre-made Rat Bckdha/E1a/BCKDA siRNA oligo Duplex | 25244 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo12039 | Pre-made Mouse Bckdha/BCKAD/E1[a] siRNA oligo Duplex | 12039 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo106994773 | Pre-made Cynomolgus/Rhesus macaque BCKDHA siRNA oligo Duplex | 106994773 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101087186 | Pre-made Cat/Feline BCKDHA siRNA oligo Duplex | 101087186 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo484488 | Pre-made Dog/Canine BCKDHA siRNA oligo Duplex | 484488 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo282149 | Pre-made Bovines/Cattle BCKDHA siRNA oligo Duplex | 282149 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100068678 | Pre-made Equine/Horse BCKDHA siRNA oligo Duplex | 100068678 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
BCKDHA antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-IP10864-Ab | Human | Anti-Human BCKDHA monoclonal antibody | mab | | Detail |
| GM-Tg-rg-IP10864-Ab | Rat | Anti-Rat BCKDHA monoclonal antibody | mab | | Detail |
| GM-Tg-mg-IP10864-Ab | Mouse | Anti-Mouse BCKDHA monoclonal antibody | mab | | Detail |
| GM-Tg-cynog-IP10864-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque BCKDHA monoclonal antibody | mab | | Detail |
| GM-Tg-felg-IP10864-Ab | Cat/Feline | Anti-Cat/Feline BCKDHA monoclonal antibody | mab | | Detail |
| GM-Tg-cang-IP10864-Ab | Dog/Canine | Anti-Dog/Canine BCKDHA monoclonal antibody | mab | | Detail |
| GM-Tg-bovg-IP10864-Ab | Bovines/Cattle | Anti-Bovines/Cattle BCKDHA monoclonal antibody | mab | | Detail |
| GM-Tg-equg-IP10864-Ab | Equine/Horse | Anti-Equine/Horse BCKDHA monoclonal antibody | mab | | Detail |
BCKDHA recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-IP10864-Ag | Human | Human BCKDHA recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-IP10864-Ag | Rat | Rat BCKDHA recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-IP10864-Ag | Mouse | Mouse BCKDHA recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-IP10864-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque BCKDHA recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-IP10864-Ag | Cat/Feline | Cat/Feline BCKDHA recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-IP10864-Ag | Dog/Canine | Dog/Canine BCKDHA recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-IP10864-Ag | Bovines/Cattle | Bovines/Cattle BCKDHA recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-IP10864-Ag | Equine/Horse | Equine/Horse BCKDHA recombinant protein | Mammalian cell | Detail |