RB1 Target & Gene Products-cDNA ORF clones/siRNA/antibody/protein

Explore RB1 gene products and cross-species research data at TarMart platform. Discover comprehensive biological information, expression tools, and therapeutic insights for Homo sapiens (human), Cynomolgus monkeys, rodents (mouse/rat), canines, felines, bovines, and equines. Your premier destination for multi-species gene research solutions
Target sublocation: Introcelluar Protein.
The protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma. [provided by RefSeq, Jul 2008]

Target ID	GM-IP10858
Target Name	RB1
Gene Group ldentifer （Target Gene ID in Homo species)	5925
Gene ID	100057080 (Equus caballus), 101101356 (Felis catus), 19645 (Mus musculus), 24708 (Rattus norvegicus) 476915 (Canis lupus familiaris), 534712 (Bos taurus), 5925 (Homo sapiens), 704871 (Macaca mulatta)
Target Alternative Names	OSRC,P105-RB,PP110,PPP1R130,RB,RB1,RB11,Rb,Rb-1,Rb1,Retinoblastoma-associated protein,p105-Rb,p110-RB1,pRb,pRb (Rb),pp105,pp110
Uniprot Accession	P13405,P33568,P06400
Protein Sub-location	Introcelluar Protein
Category	Life Science Target
Disease	cancer
Gene Ensembl	ENSECAG00000014575, ENSMUSG00000022105, ENSBTAG00000006640, ENSG00000139687, ENSMMUG00000007891
Target Classification	Nuclear Receptors

Pre-made viral vector of RB1 cDNA Clones/ORF Plasmid

Cat No.	Product Name	NMID	GeneID	Species	Type	Marker	Fusion Tag	Promoter	Detail
pGMLP001995	Human RB1/OSRC/p105-Rb Lentivirus plasmid	NM_000321.2	5925	Human	Lentivirus plasmid	ZsGreen	3xflag (C-Terminal)	CMV	Detail
pGMLP005689	Human RB1/OSRC/p105-Rb Lentivirus plasmid	NM_000321.2	5925	Human	Lentivirus plasmid	ZsGreen	3xflag (C-Terminal)	CMV	Detail
vGMLP001995	Human RB1/OSRC/p105-Rb Lentivirus particle	NM_000321.2	5925	Human	Lentivirus particle	ZsGreen	3xflag (C-Terminal)	CMV	Detail
vGMLP005689	Human RB1/OSRC/p105-Rb Lentivirus particle	NM_000321.2	5925	Human	Lentivirus particle	ZsGreen	3xflag (C-Terminal)	CMV	Detail
pGMLPm004767	Mouse Rb1/pRb/Rb Lentivirus plasmid	NM_009029.2	19645	Mouse	Lentivirus plasmid	ZsGreen	3xflag (C-Terminal)	CMV	Detail
vGMLPm004767	Mouse Rb1/pRb/Rb Lentivirus particle	NM_009029.2	19645	Mouse	Lentivirus particle	ZsGreen	3xflag (C-Terminal)	CMV	Detail

RB1 siRNA/miRNA/oligo for RNA interfence (RNAi)

Cat No.	Product Name	GeneID	Species	Grade	Detail
pGMoligo5925	Pre-made Human RB1/RB/pRb siRNA oligo Duplex	5925	Human	In-vitro grade; in-vivo grade	Detail
pGMoligo24708	Pre-made Rat Rb1 siRNA oligo Duplex	24708	Rat	In-vitro grade; in-vivo grade	Detail
pGMoligo19645	Pre-made Mouse Rb1/Rb/pRb siRNA oligo Duplex	19645	Mouse	In-vitro grade; in-vivo grade	Detail
pGMoligo704871	Pre-made Cynomolgus/Rhesus macaque RB1 siRNA oligo Duplex	704871	Cynomolgus/Rhesus macaque	In-vitro grade; in-vivo grade	Detail
pGMoligo101101356	Pre-made Cat/Feline RB1 siRNA oligo Duplex	101101356	Cat/Feline	In-vitro grade; in-vivo grade	Detail
pGMoligo476915	Pre-made Dog/Canine RB1 siRNA oligo Duplex	476915	Dog/Canine	In-vitro grade; in-vivo grade	Detail
pGMoligo534712	Pre-made Bovines/Cattle RB1/RB11/PP110 siRNA oligo Duplex	534712	Bovines/Cattle	In-vitro grade; in-vivo grade	Detail
pGMoligo100057080	Pre-made Equine/Horse RB1 siRNA oligo Duplex	100057080	Equine/Horse	In-vitro grade; in-vivo grade	Detail

RB1 antibody/GMab

Cat No.	Species	Antibody Name	Format	Detail
GM-Tg-hg-IP10858-Ab	Human	Anti-Human RB1 monoclonal antibody	mab	Detail
GM-Tg-rg-IP10858-Ab	Rat	Anti-Rat RB1 monoclonal antibody	mab	Detail
GM-Tg-mg-IP10858-Ab	Mouse	Anti-Mouse RB1 monoclonal antibody	mab	Detail
GM-Tg-cynog-IP10858-Ab	Cynomolgus/Rhesus macaque	Anti-Cynomolgus/Rhesus macaque RB1 monoclonal antibody	mab	Detail
GM-Tg-felg-IP10858-Ab	Cat/Feline	Anti-Cat/Feline RB1 monoclonal antibody	mab	Detail
GM-Tg-cang-IP10858-Ab	Dog/Canine	Anti-Dog/Canine RB1 monoclonal antibody	mab	Detail
GM-Tg-bovg-IP10858-Ab	Bovines/Cattle	Anti-Bovines/Cattle RB1 monoclonal antibody	mab	Detail
GM-Tg-equg-IP10858-Ab	Equine/Horse	Anti-Equine/Horse RB1 monoclonal antibody	mab	Detail

RB1 recombinant protein

Cat No.	Species	Antigen Name	Expression Platform	Detail
GM-Tg-hg-IP10858-Ag	Human	Human RB1 recombinant protein	Mammalian cell	Detail
GM-Tg-rg-IP10858-Ag	Rat	Rat RB1 recombinant protein	Mammalian cell	Detail
GM-Tg-mg-IP10858-Ag	Mouse	Mouse RB1 recombinant protein	Mammalian cell	Detail
GM-Tg-cynog-IP10858-Ag	Cynomolgus/Rhesus macaque	Cynomolgus/Rhesus macaque RB1 recombinant protein	Mammalian cell	Detail
GM-Tg-felg-IP10858-Ag	Cat/Feline	Cat/Feline RB1 recombinant protein	Mammalian cell	Detail
GM-Tg-cang-IP10858-Ag	Dog/Canine	Dog/Canine RB1 recombinant protein	Mammalian cell	Detail
GM-Tg-bovg-IP10858-Ag	Bovines/Cattle	Bovines/Cattle RB1 recombinant protein	Mammalian cell	Detail
GM-Tg-equg-IP10858-Ag	Equine/Horse	Equine/Horse RB1 recombinant protein	Mammalian cell	Detail