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insights for Homo sapiens (human), Cynomolgus monkeys, rodents
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Target
sublocation: Introcelluar Protein.
This gene encodes a member of the Ras family of small GTPases. The encoded protein undergoes a change in conformational state and activity, depending on whether it is bound to GTP or GDP. This protein is activated by several types of guanine nucleotide exchange factors (GEFs), and inactivated by two groups of GTPase-activating proteins (GAPs). The activation status of the encoded protein is therefore affected by the balance of intracellular levels of GEFs and GAPs. The encoded protein regulates signaling pathways that affect cell proliferation and adhesion, and may play a role in tumor malignancy. Pseudogenes of this gene have been defined on chromosomes 14 and 17. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2014]
| Target ID |
GM-IP10848
|
| Target Name |
RAP1A
|
Gene Group ldentifer (Target Gene ID in Homo
species)
|
5906
|
| Gene ID |
100058930 (Equus caballus), 101094942 (Felis catus), 109905 (Mus musculus), 282031 (Bos taurus) 295347 (Rattus norvegicus), 483225 (Canis lupus familiaris), 5906 (Homo sapiens), 704404 (Macaca mulatta)
|
| Target Alternative Names |
C21KG,G-22K,GTP-binding protein smg p21A,KREV-1,KREV1,Krev-1,RAP-1A,RAP1,RAP1A,Rap1,Rap1a,Ras-related protein Krev-1,Ras-related protein Rap-1A,SMGP21,rap 1A
|
| Uniprot Accession |
P62835,P62833,P62836,P62834
|
| Protein Sub-location |
Introcelluar Protein
|
| Category |
Life Science Target
|
| Disease |
cancer
|
| Gene Ensembl |
ENSECAG00000016434, ENSMUSG00000068798, ENSBTAG00000050904, ENSCAFG00845008254, ENSG00000116473, ENSMMUG00000014486
|
Pre-made viral vector of RAP1A cDNA Clones/ORF Plasmid
RAP1A siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo5906 | Pre-made Human RAP1A/RAP1/C21KG siRNA oligo Duplex | 5906 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo295347 | Pre-made Rat Rap1a/RAP-1A/rap 1A siRNA oligo Duplex | 295347 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo109905 | Pre-made Mouse Rap1a/Rap1/G-22K siRNA oligo Duplex | 109905 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo704404 | Pre-made Cynomolgus/Rhesus macaque RAP1A siRNA oligo Duplex | 704404 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101094942 | Pre-made Cat/Feline RAP1A siRNA oligo Duplex | 101094942 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo483225 | Pre-made Dog/Canine RAP1A siRNA oligo Duplex | 483225 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo282031 | Pre-made Bovines/Cattle RAP1A siRNA oligo Duplex | 282031 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100058930 | Pre-made Equine/Horse RAP1A siRNA oligo Duplex | 100058930 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
RAP1A antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-IP10848-Ab | Human | Anti-Human RAP1A monoclonal antibody | mab | | Detail |
| GM-Tg-rg-IP10848-Ab | Rat | Anti-Rat RAP1A monoclonal antibody | mab | | Detail |
| GM-Tg-mg-IP10848-Ab | Mouse | Anti-Mouse RAP1A monoclonal antibody | mab | | Detail |
| GM-Tg-cynog-IP10848-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque RAP1A monoclonal antibody | mab | | Detail |
| GM-Tg-felg-IP10848-Ab | Cat/Feline | Anti-Cat/Feline RAP1A monoclonal antibody | mab | | Detail |
| GM-Tg-cang-IP10848-Ab | Dog/Canine | Anti-Dog/Canine RAP1A monoclonal antibody | mab | | Detail |
| GM-Tg-bovg-IP10848-Ab | Bovines/Cattle | Anti-Bovines/Cattle RAP1A monoclonal antibody | mab | | Detail |
| GM-Tg-equg-IP10848-Ab | Equine/Horse | Anti-Equine/Horse RAP1A monoclonal antibody | mab | | Detail |
RAP1A recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-IP10848-Ag | Human | Human RAP1A recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-IP10848-Ag | Rat | Rat RAP1A recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-IP10848-Ag | Mouse | Mouse RAP1A recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-IP10848-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque RAP1A recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-IP10848-Ag | Cat/Feline | Cat/Feline RAP1A recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-IP10848-Ag | Dog/Canine | Dog/Canine RAP1A recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-IP10848-Ag | Bovines/Cattle | Bovines/Cattle RAP1A recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-IP10848-Ag | Equine/Horse | Equine/Horse RAP1A recombinant protein | Mammalian cell | Detail |