Explore ACTA2 gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Introcelluar Protein.
This gene encodes one of six different actin proteins. Actins are highly conserved proteins that are involved in cell motility, structure, integrity, and intercellular signaling. The encoded protein is a smooth muscle actin that is involved in vascular contractility and blood pressure homeostasis. Mutations in this gene cause a variety of vascular diseases, such as thoracic aortic disease, coronary artery disease, stroke, and Moyamoya disease, as well as multisystemic smooth muscle dysfunction syndrome. [provided by RefSeq, Sep 2017]
| Target ID |
GM-IP10843
|
| Target Name |
ACTA2
|
Gene Group ldentifer (Target Gene ID in Homo
species)
|
59
|
| Gene ID |
100062175 (Equus caballus), 100427024 (Macaca mulatta), 101093547 (Felis catus), 11475 (Mus musculus) 477587 (Canis lupus familiaris), 515610 (Bos taurus), 59 (Homo sapiens), 81633 (Rattus norvegicus)
|
| Target Alternative Names |
0610041G09Rik,ACTA2,ACTSA,Acta2,Actin,Actvs,Alpha-actin-2,Cell growth-inhibiting gene 46 protein,SMAalpha,SMDYS,SMalphaA,a-SMA,alphaSMA,aortic smooth muscle
|
| Uniprot Accession |
P62737,P62739,P62736,P62738
|
| Protein Sub-location |
Introcelluar Protein
|
| Category |
Life Science Target
|
| Disease |
cancer
|
| Gene Ensembl |
ENSECAG00000015145, ENSMMUG00000009341, ENSMUSG00000035783, ENSCAFG00845029801, ENSBTAG00000014614, ENSG00000107796
|
Pre-made viral vector of ACTA2 cDNA Clones/ORF Plasmid
ACTA2 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo59 | Pre-made Human ACTA2/ACTSA/SMDYS siRNA oligo Duplex | 59 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo81633 | Pre-made Rat Acta2 siRNA oligo Duplex | 81633 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo11475 | Pre-made Mouse Acta2/Actvs/a-SMA siRNA oligo Duplex | 11475 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100427024 | Pre-made Cynomolgus/Rhesus macaque ACTA2 siRNA oligo Duplex | 100427024 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101093547 | Pre-made Cat/Feline ACTA2 siRNA oligo Duplex | 101093547 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo477587 | Pre-made Dog/Canine ACTA2 siRNA oligo Duplex | 477587 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo515610 | Pre-made Bovines/Cattle ACTA2 siRNA oligo Duplex | 515610 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100062175 | Pre-made Equine/Horse ACTA2 siRNA oligo Duplex | 100062175 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
ACTA2 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-IP10843-Ab | Human | Anti-Human ACTA2 monoclonal antibody | mab | | Detail |
| GM-Tg-rg-IP10843-Ab | Rat | Anti-Rat ACTA2 monoclonal antibody | mab | | Detail |
| GM-Tg-mg-IP10843-Ab | Mouse | Anti-Mouse ACTA2 monoclonal antibody | mab | | Detail |
| GM-Tg-cynog-IP10843-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque ACTA2 monoclonal antibody | mab | | Detail |
| GM-Tg-felg-IP10843-Ab | Cat/Feline | Anti-Cat/Feline ACTA2 monoclonal antibody | mab | | Detail |
| GM-Tg-cang-IP10843-Ab | Dog/Canine | Anti-Dog/Canine ACTA2 monoclonal antibody | mab | | Detail |
| GM-Tg-bovg-IP10843-Ab | Bovines/Cattle | Anti-Bovines/Cattle ACTA2 monoclonal antibody | mab | | Detail |
| GM-Tg-equg-IP10843-Ab | Equine/Horse | Anti-Equine/Horse ACTA2 monoclonal antibody | mab | | Detail |
ACTA2 recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-IP10843-Ag | Human | Human ACTA2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-IP10843-Ag | Rat | Rat ACTA2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-IP10843-Ag | Mouse | Mouse ACTA2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-IP10843-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque ACTA2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-IP10843-Ag | Cat/Feline | Cat/Feline ACTA2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-IP10843-Ag | Dog/Canine | Dog/Canine ACTA2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-IP10843-Ag | Bovines/Cattle | Bovines/Cattle ACTA2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-IP10843-Ag | Equine/Horse | Equine/Horse ACTA2 recombinant protein | Mammalian cell | Detail |