Explore KMT2C gene products and cross-species
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biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Introcelluar Protein.
This gene is a member of the myeloid/lymphoid or mixed-lineage leukemia (MLL) family and encodes a nuclear protein with an AT hook DNA-binding domain, a DHHC-type zinc finger, six PHD-type zinc fingers, a SET domain, a post-SET domain and a RING-type zinc finger. This protein is a member of the ASC-2/NCOA6 complex (ASCOM), which possesses histone methylation activity and is involved in transcriptional coactivation. [provided by RefSeq, Jul 2008]
| Target ID |
GM-IP10802
|
| Target Name |
KMT2C
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
58508
|
| Gene ID |
100064812 (Equus caballus), 101084095 (Felis catus), 231051 (Mus musculus), 502710 (Rattus norvegicus)
58508 (Homo sapiens), 611094 (Canis lupus familiaris), 716753 (Macaca mulatta), 789336 (Bos taurus)
|
| Target Alternative Names |
E330008K23Rik,HALR,Histone-lysine N-methyltransferase 2C,Homologous to ALR protein,KLEFS2,KMT2C,Kmt2c,Lysine N-methyltransferase 2C,MLL3,Mll3,Myeloid/lymphoid or mixed-lineage leukemia protein 3
|
| Uniprot Accession |
Q8BRH4,Q8NEZ4
|
| Protein Sub-location |
Introcelluar Protein
|
| Category |
Life Science Target
|
| Disease |
cancer
|
| Gene Ensembl |
ENSECAG00000022544, ENSMUSG00000038056, ENSG00000055609, ENSMMUG00000007212, ENSBTAG00000024199
|
KMT2C siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo58508 | Pre-made Human KMT2C/HALR/MLL3 siRNA oligo Duplex | 58508 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo502710 | Pre-made Rat Kmt2c siRNA oligo Duplex | 502710 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo231051 | Pre-made Mouse Kmt2c/HALR/Mll3 siRNA oligo Duplex | 231051 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo716753 | Pre-made Cynomolgus/Rhesus macaque KMT2C/MLL3 siRNA oligo Duplex | 716753 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101084095 | Pre-made Cat/Feline KMT2C/MLL3 siRNA oligo Duplex | 101084095 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo611094 | Pre-made Dog/Canine KMT2C/MLL3 siRNA oligo Duplex | 611094 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo789336 | Pre-made Bovines/Cattle KMT2C/MLL3 siRNA oligo Duplex | 789336 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100064812 | Pre-made Equine/Horse KMT2C siRNA oligo Duplex | 100064812 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
KMT2C antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-IP10802-Ab | Human | Anti-Human KMT2C monoclonal antibody | mab | | Detail |
| GM-Tg-rg-IP10802-Ab | Rat | Anti-Rat KMT2C monoclonal antibody | mab | | Detail |
| GM-Tg-mg-IP10802-Ab | Mouse | Anti-Mouse KMT2C monoclonal antibody | mab | | Detail |
| GM-Tg-cynog-IP10802-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque KMT2C monoclonal antibody | mab | | Detail |
| GM-Tg-felg-IP10802-Ab | Cat/Feline | Anti-Cat/Feline KMT2C monoclonal antibody | mab | | Detail |
| GM-Tg-cang-IP10802-Ab | Dog/Canine | Anti-Dog/Canine KMT2C monoclonal antibody | mab | | Detail |
| GM-Tg-bovg-IP10802-Ab | Bovines/Cattle | Anti-Bovines/Cattle KMT2C monoclonal antibody | mab | | Detail |
| GM-Tg-equg-IP10802-Ab | Equine/Horse | Anti-Equine/Horse KMT2C monoclonal antibody | mab | | Detail |
KMT2C recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-IP10802-Ag | Human | Human KMT2C recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-IP10802-Ag | Rat | Rat KMT2C recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-IP10802-Ag | Mouse | Mouse KMT2C recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-IP10802-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque KMT2C recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-IP10802-Ag | Cat/Feline | Cat/Feline KMT2C recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-IP10802-Ag | Dog/Canine | Dog/Canine KMT2C recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-IP10802-Ag | Bovines/Cattle | Bovines/Cattle KMT2C recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-IP10802-Ag | Equine/Horse | Equine/Horse KMT2C recombinant protein | Mammalian cell | Detail |
