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Target
sublocation: Introcelluar Protein.
The protein encoded by this gene belongs to the arginine N-methyltransferase family, which catalyze the sequential transfer of methyl group from S-adenosyl-L-methionine to the side chain nitrogens of arginine residues within proteins, to form methylated arginine derivatives and S-adenosyl-L-homocysteine. This protein can catalyze both, the formation of omega-N monomethylarginine and asymmetrical dimethylarginine, with a strong preference for the latter. It specifically mediates the asymmetric dimethylation of Arg2 of histone H3, and the methylated form represents a specific tag for epigenetic transcriptional repression. This protein also forms a complex with, and methylates DNA polymerase beta, resulting in stimulation of polymerase activity by enhancing DNA binding and processivity. [provided by RefSeq, Sep 2011]
| Target ID |
GM-IP10025
|
| Target Name |
PRMT6
|
Gene Group ldentifer (Target Gene ID in Homo
species)
|
55170
|
| Gene ID |
100060260 (Equus caballus), 101093626 (Felis catus), 295384 (Rattus norvegicus), 490133 (Canis lupus familiaris) 540228 (Bos taurus), 55170 (Homo sapiens), 694284 (Macaca mulatta), 99890 (Mus musculus)
|
| Target Alternative Names |
HRMT1L6,Heterogeneous nuclear ribonucleoprotein methyltransferase-like protein 6,Histone-arginine N-methyltransferase PRMT6,Hrmt1l6,PRMT6,Prmt6,Protein arginine N-methyltransferase 6
|
| Uniprot Accession |
Q5E9L5,Q96LA8,Q6NZB1
|
| Protein Sub-location |
Introcelluar Protein
|
| Category |
Life Science Target
|
| Gene Ensembl |
ENSECAG00000003427, ENSCAFG00845010440, ENSBTAG00000039951, ENSG00000198890, ENSMMUG00000056038, ENSMUSG00000049300
|
Pre-made viral vector of PRMT6 cDNA Clones/ORF Plasmid
PRMT6 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo55170 | Pre-made Human PRMT6/HRMT1L6 siRNA oligo Duplex | 55170 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo295384 | Pre-made Rat Prmt6/Hrmt1l6 siRNA oligo Duplex | 295384 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo99890 | Pre-made Mouse Prmt6/Hrmt1l6 siRNA oligo Duplex | 99890 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo694284 | Pre-made Cynomolgus/Rhesus macaque PRMT6 siRNA oligo Duplex | 694284 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101093626 | Pre-made Cat/Feline PRMT6 siRNA oligo Duplex | 101093626 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo490133 | Pre-made Dog/Canine PRMT6 siRNA oligo Duplex | 490133 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo540228 | Pre-made Bovines/Cattle PRMT6/HRMT1L6 siRNA oligo Duplex | 540228 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100060260 | Pre-made Equine/Horse PRMT6 siRNA oligo Duplex | 100060260 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
PRMT6 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-IP10025-Ab | Human | Anti-Human PRMT6 monoclonal antibody | mab | | Detail |
| GM-Tg-rg-IP10025-Ab | Rat | Anti-Rat PRMT6 monoclonal antibody | mab | | Detail |
| GM-Tg-mg-IP10025-Ab | Mouse | Anti-Mouse PRMT6 monoclonal antibody | mab | | Detail |
| GM-Tg-cynog-IP10025-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque PRMT6 monoclonal antibody | mab | | Detail |
| GM-Tg-felg-IP10025-Ab | Cat/Feline | Anti-Cat/Feline PRMT6 monoclonal antibody | mab | | Detail |
| GM-Tg-cang-IP10025-Ab | Dog/Canine | Anti-Dog/Canine PRMT6 monoclonal antibody | mab | | Detail |
| GM-Tg-bovg-IP10025-Ab | Bovines/Cattle | Anti-Bovines/Cattle PRMT6 monoclonal antibody | mab | | Detail |
| GM-Tg-equg-IP10025-Ab | Equine/Horse | Anti-Equine/Horse PRMT6 monoclonal antibody | mab | | Detail |
PRMT6 recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-IP10025-Ag | Human | Human PRMT6 recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-IP10025-Ag | Rat | Rat PRMT6 recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-IP10025-Ag | Mouse | Mouse PRMT6 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-IP10025-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque PRMT6 recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-IP10025-Ag | Cat/Feline | Cat/Feline PRMT6 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-IP10025-Ag | Dog/Canine | Dog/Canine PRMT6 recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-IP10025-Ag | Bovines/Cattle | Bovines/Cattle PRMT6 recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-IP10025-Ag | Equine/Horse | Equine/Horse PRMT6 recombinant protein | Mammalian cell | Detail |