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Target
sublocation: Introcelluar Protein.
Many different human endogenous retrovirus (HERV) families are expressed in normal placental tissue at high levels, suggesting that HERVs are functionally important in reproduction. This gene is part of an HERV provirus on human chromosome 19 that has inactivating mutations in the gag and pol genes. This envelope glycoprotein gene appears to have been selectively preserved. The gene's protein product is expressed in the placenta and acts as a syncytin in Old World monkeys, but has lost the fusogenic activity in humans and other primate lineages. [provided by RefSeq, Jun 2015]
| Target ID |
GM-IP0770
|
| Target Name |
ERVV-2
|
Gene Group ldentifer (Target Gene ID in Homo
species)
|
100271846
|
| Gene ID |
100271846 (Homo sapiens), 100429036 (Macaca mulatta)
|
| Target Alternative Names |
ENV,ENVV2,ERVV-2,Endogenous retrovirus group V member 2 Env polyprotein,HERV-V2,HERV-V_19q13.41 provirus ancestral Env polyprotein 2,envV2
|
| Uniprot Accession |
B6SEH9
|
| Protein Sub-location |
Introcelluar Protein
|
| Gene Ensembl |
ENSG00000268964, ENSMMUG00000056370
|
ERVV-2 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo100271846 | Pre-made Human ERVV-2/ENVV2/HERV-V2 siRNA oligo Duplex | 100271846 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100429036 | Pre-made Cynomolgus/Rhesus macaque ERVV-2/ENV/envV2 siRNA oligo Duplex | 100429036 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
ERVV-2 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-IP0770-Ab | Human | Anti-Human ERVV-2 monoclonal antibody | mab | | Detail |
| GM-Tg-cynog-IP0770-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque ERVV-2 monoclonal antibody | mab | | Detail |
ERVV-2 recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-IP0770-Ag | Human | Human ERVV-2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-IP0770-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque ERVV-2 recombinant protein | Mammalian cell | Detail |