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Target
sublocation: Introcelluar Protein.
The mitochondrial oxidation of long-chain fatty acids is initiated by the sequential action of carnitine palmitoyltransferase I (which is located in the outer membrane and is detergent-labile) and carnitine palmitoyltransferase II (which is located in the inner membrane and is detergent-stable), together with a carnitine-acylcarnitine translocase. CPT I is the key enzyme in the carnitine-dependent transport across the mitochondrial inner membrane and its deficiency results in a decreased rate of fatty acid beta-oxidation. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
| Target ID |
GM-IP0608
|
| Target Name |
CPT1A
|
Gene Group ldentifer (Target Gene ID in Homo
species)
|
1374
|
| Gene ID |
100009716 (Equus caballus), 101096105 (Felis catus), 12894 (Mus musculus), 1374 (Homo sapiens) 25757 (Rattus norvegicus), 403583 (Canis lupus familiaris), 506812 (Bos taurus), 709837 (Macaca mulatta)
|
| Target Alternative Names |
C730027G07,CPT-Ia,CPT1,CPT1-L,CPT1A,CPTI,CPTI-L),Carnitine O-palmitoyltransferase 1,Carnitine O-palmitoyltransferase I,Carnitine palmitoyltransferase 1A,Cpt1,Cpt1a,L-CPT1,Succinyltransferase CPT1A,liver isoform,liver isoform (CPT I
|
| Uniprot Accession |
Q68Y62,P97742,P50416,P32198
|
| Protein Sub-location |
Introcelluar Protein
|
| Disease from KEGG |
PPAR signaling pathway, Adipocytokine signaling pathway, Insulin resistance, Alcoholic liver disease
|
| Gene Ensembl |
ENSECAG00000016852, ENSMUSG00000024900, ENSG00000110090, ENSCAFG00845006637, ENSBTAG00000021999, ENSMMUG00000001780
|
Pre-made viral vector of CPT1A cDNA Clones/ORF Plasmid
CPT1A siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo1374 | Pre-made Human CPT1A/CPT1/CPT1-L siRNA oligo Duplex | 1374 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo25757 | Pre-made Rat Cpt1a/CPT-Ia siRNA oligo Duplex | 25757 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo12894 | Pre-made Mouse Cpt1a/CPTI/Cpt1 siRNA oligo Duplex | 12894 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo709837 | Pre-made Cynomolgus/Rhesus macaque CPT1A siRNA oligo Duplex | 709837 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101096105 | Pre-made Cat/Feline CPT1A siRNA oligo Duplex | 101096105 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo403583 | Pre-made Dog/Canine CPT1A/CPT1 siRNA oligo Duplex | 403583 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo506812 | Pre-made Bovines/Cattle CPT1A siRNA oligo Duplex | 506812 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100009716 | Pre-made Equine/Horse CPT1A siRNA oligo Duplex | 100009716 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
CPT1A antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-IP0608-Ab | Human | Anti-Human CPT1A monoclonal antibody | mab | | Detail |
| GM-Tg-rg-IP0608-Ab | Rat | Anti-Rat CPT1A monoclonal antibody | mab | | Detail |
| GM-Tg-mg-IP0608-Ab | Mouse | Anti-Mouse CPT1A monoclonal antibody | mab | | Detail |
| GM-Tg-cynog-IP0608-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque CPT1A monoclonal antibody | mab | | Detail |
| GM-Tg-felg-IP0608-Ab | Cat/Feline | Anti-Cat/Feline CPT1A monoclonal antibody | mab | | Detail |
| GM-Tg-cang-IP0608-Ab | Dog/Canine | Anti-Dog/Canine CPT1A monoclonal antibody | mab | | Detail |
| GM-Tg-bovg-IP0608-Ab | Bovines/Cattle | Anti-Bovines/Cattle CPT1A monoclonal antibody | mab | | Detail |
| GM-Tg-equg-IP0608-Ab | Equine/Horse | Anti-Equine/Horse CPT1A monoclonal antibody | mab | | Detail |
CPT1A recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-IP0608-Ag | Human | Human CPT1A recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-IP0608-Ag | Rat | Rat CPT1A recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-IP0608-Ag | Mouse | Mouse CPT1A recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-IP0608-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque CPT1A recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-IP0608-Ag | Cat/Feline | Cat/Feline CPT1A recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-IP0608-Ag | Dog/Canine | Dog/Canine CPT1A recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-IP0608-Ag | Bovines/Cattle | Bovines/Cattle CPT1A recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-IP0608-Ag | Equine/Horse | Equine/Horse CPT1A recombinant protein | Mammalian cell | Detail |