Explore COX IV/COXIV/COX4I1 gene products and cross-species
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biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Introcelluar Protein.
Cytochrome c oxidase (COX) is the terminal enzyme of the mitochondrial respiratory chain. It is a multi-subunit enzyme complex that couples the transfer of electrons from cytochrome c to molecular oxygen and contributes to a proton electrochemical gradient across the inner mitochondrial membrane. The complex consists of 13 mitochondrial- and nuclear-encoded subunits. The mitochondrially-encoded subunits perform the electron transfer and proton pumping activities. The functions of the nuclear-encoded subunits are unknown but they may play a role in the regulation and assembly of the complex. This gene encodes the nuclear-encoded subunit IV isoform 1 of the human mitochondrial respiratory chain enzyme. It is located at the 3' of the NOC4 (neighbor of COX4) gene in a head-to-head orientation, and shares a promoter with it. Pseudogenes related to this gene are located on chromosomes 13 and 14. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jan 2016]
| Target ID |
GM-IP0599
|
| Target Name |
COX IV/COXIV/COX4I1
|
Gene Group ldentifer (Target Gene ID in Homo
species)
|
1327
|
| Gene ID |
100056171 (Equus caballus), 101089914 (Felis catus), 12857 (Mus musculus), 1327 (Homo sapiens) 281090 (Bos taurus), 29445 (Rattus norvegicus), 479623 (Canis lupus familiaris), 693811 (Macaca mulatta)
|
| Target Alternative Names |
COX,COX IV,COX IV-1,COX4,COX4-1,COX4I1,COXIV,COXIV-1,Cox4,Cox4a,Cox4i1,Cytochrome c oxidase polypeptide IV,Cytochrome c oxidase subunit 4 isoform 1,Cytochrome c oxidase subunit IV isoform 1 (COX IV-1),IV-1,LOC101089914,MC4DN16,mitochondrial
|
| Uniprot Accession |
P19783,P13073,P00423,P10888
|
| Protein Sub-location |
Introcelluar Protein
|
| Disease from KEGG |
Metabolic pathways, Alzheimer disease
|
| Gene Ensembl |
ENSMUSG00000031818, ENSG00000131143, ENSBTAG00000016079, ENSCAFG00845004280, ENSMMUG00000006763
|
Pre-made viral vector of COX IV/COXIV/COX4I1 cDNA Clones/ORF Plasmid
COX IV/COXIV/COX4I1 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo1327 | Pre-made Human COX4I1/COX4/COXIV siRNA oligo Duplex | 1327 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo29445 | Pre-made Rat Cox4i1/Cox4/Cox4a siRNA oligo Duplex | 29445 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo12857 | Pre-made Mouse Cox4i1/COX/Cox4 siRNA oligo Duplex | 12857 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo693811 | Pre-made Cynomolgus/Rhesus macaque COX4I1 siRNA oligo Duplex | 693811 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101089914 | Pre-made Cat/Feline LOC101089914 siRNA oligo Duplex | 101089914 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo479623 | Pre-made Dog/Canine COX4I1 siRNA oligo Duplex | 479623 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo281090 | Pre-made Bovines/Cattle COX4I1/COX4 siRNA oligo Duplex | 281090 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100056171 | Pre-made Equine/Horse COX4I1/COXIV siRNA oligo Duplex | 100056171 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
COX IV/COXIV/COX4I1 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-IP0599-Ab | Human | Anti-Human COX IV/COXIV/COX4I1 monoclonal antibody | mab | | Detail |
| GM-Tg-rg-IP0599-Ab | Rat | Anti-Rat COX IV/COXIV/COX4I1 monoclonal antibody | mab | | Detail |
| GM-Tg-mg-IP0599-Ab | Mouse | Anti-Mouse COX IV/COXIV/COX4I1 monoclonal antibody | mab | | Detail |
| GM-Tg-cynog-IP0599-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque COX IV/COXIV/COX4I1 monoclonal antibody | mab | | Detail |
| GM-Tg-felg-IP0599-Ab | Cat/Feline | Anti-Cat/Feline COX IV/COXIV/COX4I1 monoclonal antibody | mab | | Detail |
| GM-Tg-cang-IP0599-Ab | Dog/Canine | Anti-Dog/Canine COX IV/COXIV/COX4I1 monoclonal antibody | mab | | Detail |
| GM-Tg-bovg-IP0599-Ab | Bovines/Cattle | Anti-Bovines/Cattle COX IV/COXIV/COX4I1 monoclonal antibody | mab | | Detail |
| GM-Tg-equg-IP0599-Ab | Equine/Horse | Anti-Equine/Horse COX IV/COXIV/COX4I1 monoclonal antibody | mab | | Detail |
COX IV/COXIV/COX4I1 recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-IP0599-Ag | Human | Human COX IV/COXIV/COX4I1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-IP0599-Ag | Rat | Rat COX IV/COXIV/COX4I1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-IP0599-Ag | Mouse | Mouse COX IV/COXIV/COX4I1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-IP0599-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque COX IV/COXIV/COX4I1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-IP0599-Ag | Cat/Feline | Cat/Feline COX IV/COXIV/COX4I1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-IP0599-Ag | Dog/Canine | Dog/Canine COX IV/COXIV/COX4I1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-IP0599-Ag | Bovines/Cattle | Bovines/Cattle COX IV/COXIV/COX4I1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-IP0599-Ag | Equine/Horse | Equine/Horse COX IV/COXIV/COX4I1 recombinant protein | Mammalian cell | Detail |