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Target
sublocation: Introcelluar Protein.
The nicotinic acetylcholine receptors (nAChRs) are members of a superfamily of ligand-gated ion channels that mediate fast signal transmission at synapses. The family member CHRNA7, which is located on chromosome 15 in a region associated with several neuropsychiatric disorders, is partially duplicated and forms a hybrid with a novel gene from the family with sequence similarity 7 (FAM7A). Alternative splicing has been observed, and two variants exist, for this hybrid gene. The N-terminally truncated products predicted by the largest open reading frames for each variant would lack the majority of the neurotransmitter-gated ion-channel ligand binding domain but retain the transmembrane region that forms the ion channel. Although current evidence supports transcription of this hybrid gene, translation of the nicotinic acetylcholine receptor-like protein-encoding open reading frames has not been confirmed. [provided by RefSeq, Jul 2008]
| Target ID |
GM-IP0544
|
| Target Name |
CHRNA7/CHRFAM7A
|
Gene Group ldentifer (Target Gene ID in Homo
species)
|
89832
|
| Gene ID |
89832 (Homo sapiens)
|
| Target Alternative Names |
CHRFAM7A,CHRNA7,CHRNA7-DR1,CHRNA7-FAM7A fusion protein,D-10,NACHRA7
|
| Uniprot Accession |
Q494W8
|
| Protein Sub-location |
Introcelluar Protein
|
| Gene Ensembl |
ENSG00000166664
|
CHRNA7/CHRFAM7A siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo89832 | Pre-made Human CHRFAM7A/D-10/CHRNA7 siRNA oligo Duplex | 89832 | Human | In-vitro grade; in-vivo grade | Detail |
CHRNA7/CHRFAM7A antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-IP0544-Ab | Human | Anti-Human CHRNA7/CHRFAM7A monoclonal antibody | mab | | Detail |
CHRNA7/CHRFAM7A recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-IP0544-Ag | Human | Human CHRNA7/CHRFAM7A recombinant protein | Mammalian cell | Detail |