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biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
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Target
sublocation: Introcelluar Protein.
The protein encoded by this gene shares a critical BH3 domain with other death-promoting proteins, such as BID, BAK, BAD and BAX, that is required for its pro-apoptotic activity, and for interaction with anti-apoptotic members of the BCL2 family, and viral survival-promoting proteins. Since the activity of this protein is suppressed in the presence of survival-promoting proteins, it is suggested as a likely target for anti-apoptotic proteins. [provided by RefSeq, Sep 2011]
| Target ID |
GM-IP0421
|
| Target Name |
BIK
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
638
|
| Gene ID |
102150906 (Equus caballus), 102155535 (Canis lupus familiaris), 114496 (Rattus norvegicus), 12124 (Mus musculus)
618614 (Bos taurus), 638 (Homo sapiens), 711479 (Macaca mulatta), 790946 (Felis catus)
|
| Target Alternative Names |
Apoptosis inducer NBK,BIK,BIP1,BP4,Bcl-2-interacting killer,Bik,Biklk,Blk,NBK,Nbk
|
| Uniprot Accession |
O70337,Q13323
|
| Protein Sub-location |
Introcelluar Protein
|
| Disease |
cancer
|
| Disease from KEGG |
Endocrine resistance
|
| Gene Ensembl |
ENSECAG00000018135, ENSMUSG00000016758, ENSBTAG00000049724, ENSG00000100290, ENSMMUG00000057131
|
| Target Classification |
Tumor-associated antigen (TAA)
|
Pre-made viral vector of BIK cDNA Clones/ORF Plasmid
BIK siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo638 | Pre-made Human BIK/BP4/NBK siRNA oligo Duplex | 638 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo114496 | Pre-made Rat Bik/Blk/Biklk siRNA oligo Duplex | 114496 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo12124 | Pre-made Mouse Bik/Blk/Nbk siRNA oligo Duplex | 12124 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo711479 | Pre-made Cynomolgus/Rhesus macaque BIK siRNA oligo Duplex | 711479 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo790946 | Pre-made Cat/Feline BIK siRNA oligo Duplex | 790946 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo102155535 | Pre-made Dog/Canine BIK siRNA oligo Duplex | 102155535 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo618614 | Pre-made Bovines/Cattle BIK siRNA oligo Duplex | 618614 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo102150906 | Pre-made Equine/Horse BIK siRNA oligo Duplex | 102150906 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
BIK antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-IP0421-Ab | Human | Anti-Human BIK monoclonal antibody | mab | | Detail |
| GM-Tg-rg-IP0421-Ab | Rat | Anti-Rat BIK monoclonal antibody | mab | | Detail |
| GM-Tg-mg-IP0421-Ab | Mouse | Anti-Mouse BIK monoclonal antibody | mab | | Detail |
| GM-Tg-cynog-IP0421-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque BIK monoclonal antibody | mab | | Detail |
| GM-Tg-felg-IP0421-Ab | Cat/Feline | Anti-Cat/Feline BIK monoclonal antibody | mab | | Detail |
| GM-Tg-cang-IP0421-Ab | Dog/Canine | Anti-Dog/Canine BIK monoclonal antibody | mab | | Detail |
| GM-Tg-bovg-IP0421-Ab | Bovines/Cattle | Anti-Bovines/Cattle BIK monoclonal antibody | mab | | Detail |
| GM-Tg-equg-IP0421-Ab | Equine/Horse | Anti-Equine/Horse BIK monoclonal antibody | mab | | Detail |
BIK recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-IP0421-Ag | Human | Human BIK recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-IP0421-Ag | Rat | Rat BIK recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-IP0421-Ag | Mouse | Mouse BIK recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-IP0421-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque BIK recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-IP0421-Ag | Cat/Feline | Cat/Feline BIK recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-IP0421-Ag | Dog/Canine | Dog/Canine BIK recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-IP0421-Ag | Bovines/Cattle | Bovines/Cattle BIK recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-IP0421-Ag | Equine/Horse | Equine/Horse BIK recombinant protein | Mammalian cell | Detail |
