SPTLC2 Target & Gene Products-cDNA ORF clones/siRNA/antibody/protein

Explore SPTLC2 gene products and cross-species research data at TarMart platform. Discover comprehensive biological information, expression tools, and therapeutic insights for Homo sapiens (human), Cynomolgus monkeys, rodents (mouse/rat), canines, felines, bovines, and equines. Your premier destination for multi-species gene research solutions
Target sublocation: Introcelluar Protein.
This gene encodes a long chain base subunit of serine palmitoyltransferase. Serine palmitoyltransferase, which consists of two different subunits, is the key enzyme in sphingolipid biosynthesis. It catalyzes the pyridoxal-5-prime-phosphate-dependent condensation of L-serine and palmitoyl-CoA to 3-oxosphinganine. Mutations in this gene were identified in patients with hereditary sensory neuropathy type I. [provided by RefSeq, Mar 2011]

Target ID	GM-IP0249
Target Name	SPTLC2
Gene Group ldentifer （Target Gene ID in Homo species)	9517
Gene ID	100059392 (Equus caballus), 101081055 (Felis catus), 20773 (Mus musculus), 366697 (Rattus norvegicus) 480403 (Canis lupus familiaris), 537972 (Bos taurus), 707625 (Macaca mulatta), 9517 (Homo sapiens)
Target Alternative Names	HSN1C,LCB 2,LCB2,LCB2A,LCB2a,Long chain base biosynthesis protein 2 (LCB 2),Long chain base biosynthesis protein 2a (LCB2a),NSAN1C,Pomt2,SPT 2,SPT2,SPTLC2,Serine palmitoyltransferase 2,Serine-palmitoyl-CoA transferase 2 (SPT 2),Spt2,Sptlc2,hLCB2a
Uniprot Accession	P97363,Q3B7D2,O15270
Protein Sub-location	Introcelluar Protein
Category	Therapeutics Target
Disease from KEGG	Metabolic pathways, Sphingolipid signaling pathway, Sphingolipid metabolism
Gene Ensembl	ENSECAG00000021294, ENSMUSG00000021036, ENSCAFG00845007510, ENSBTAG00000020480, ENSMMUG00000013556, ENSG00000100596

Pre-made viral vector of SPTLC2 cDNA Clones/ORF Plasmid

Cat No.	Product Name	NMID	GeneID	Species	Type	Marker	Fusion Tag	Promoter	Detail
pGMLP001132	Human SPTLC2/hLCB2a/HSN1C Lentivirus plasmid	NM_004863	9517	Human	Lentivirus plasmid	ZsGreen	3xflag (C-Terminal)	CMV	Detail
vGMLP001132	Human SPTLC2/hLCB2a/HSN1C Lentivirus particle	NM_004863	9517	Human	Lentivirus particle	ZsGreen	3xflag (C-Terminal)	CMV	Detail
pGMAD000901	Mouse Sptlc2/LCB/LCB2 Adenovirus plasmid	NM_011479.4	20773	Mouse	Adenovirus plasmid	Null	Null	CMV	Detail
pGMLPm001095	Mouse Sptlc2/LCB2/LCB2a Lentivirus plasmid	NM_011479	20773	Mouse	Lentivirus plasmid	ZsGreen	3xflag (C-Terminal)	CMV	Detail
vGMAD000901	Mouse Sptlc2/LCB/LCB2 Adenovirus particle	NM_011479.4	20773	Mouse	Adenovirus particle	Null	Null	CMV	Detail
vGMLPm001095	Mouse Sptlc2/LCB2/LCB2a Lentivirus particle	NM_011479	20773	Mouse	Lentivirus particle	ZsGreen	3xflag (C-Terminal)	CMV	Detail

SPTLC2 siRNA/miRNA/oligo for RNA interfence (RNAi)

Cat No.	Product Name	GeneID	Species	Grade	Detail
pGMoligo9517	Pre-made Human SPTLC2/LCB2/SPT2 siRNA oligo Duplex	9517	Human	In-vitro grade; in-vivo grade	Detail
pGMoligo366697	Pre-made Rat Sptlc2/LCB 2/Pomt2 siRNA oligo Duplex	366697	Rat	In-vitro grade; in-vivo grade	Detail
pGMoligo20773	Pre-made Mouse Sptlc2/LCB2/Spt2 siRNA oligo Duplex	20773	Mouse	In-vitro grade; in-vivo grade	Detail
pGMoligo707625	Pre-made Cynomolgus/Rhesus macaque SPTLC2 siRNA oligo Duplex	707625	Cynomolgus/Rhesus macaque	In-vitro grade; in-vivo grade	Detail
pGMoligo101081055	Pre-made Cat/Feline SPTLC2 siRNA oligo Duplex	101081055	Cat/Feline	In-vitro grade; in-vivo grade	Detail
pGMoligo480403	Pre-made Dog/Canine SPTLC2 siRNA oligo Duplex	480403	Dog/Canine	In-vitro grade; in-vivo grade	Detail
pGMoligo537972	Pre-made Bovines/Cattle SPTLC2 siRNA oligo Duplex	537972	Bovines/Cattle	In-vitro grade; in-vivo grade	Detail
pGMoligo100059392	Pre-made Equine/Horse SPTLC2 siRNA oligo Duplex	100059392	Equine/Horse	In-vitro grade; in-vivo grade	Detail

SPTLC2 antibody/GMab

Cat No.	Species	Antibody Name	Format	Classified by tag	Detail
GM-Tg-hg-IP0249-Ab	Human	Anti-Human SPTLC2 monoclonal antibody	mab	Therapeutics Target antibody	Detail
GM-Tg-rg-IP0249-Ab	Rat	Anti-Rat SPTLC2 monoclonal antibody	mab	Therapeutics Target antibody	Detail
GM-Tg-mg-IP0249-Ab	Mouse	Anti-Mouse SPTLC2 monoclonal antibody	mab	Therapeutics Target antibody	Detail
GM-Tg-cynog-IP0249-Ab	Cynomolgus/Rhesus macaque	Anti-Cynomolgus/Rhesus macaque SPTLC2 monoclonal antibody	mab	Therapeutics Target antibody	Detail
GM-Tg-felg-IP0249-Ab	Cat/Feline	Anti-Cat/Feline SPTLC2 monoclonal antibody	mab	Therapeutics Target antibody	Detail
GM-Tg-cang-IP0249-Ab	Dog/Canine	Anti-Dog/Canine SPTLC2 monoclonal antibody	mab	Therapeutics Target antibody	Detail
GM-Tg-bovg-IP0249-Ab	Bovines/Cattle	Anti-Bovines/Cattle SPTLC2 monoclonal antibody	mab	Therapeutics Target antibody	Detail
GM-Tg-equg-IP0249-Ab	Equine/Horse	Anti-Equine/Horse SPTLC2 monoclonal antibody	mab	Therapeutics Target antibody	Detail

SPTLC2 recombinant protein

Cat No.	Species	Antigen Name	Expression Platform	Detail
GM-Tg-hg-IP0249-Ag	Human	Human SPTLC2 recombinant protein	Mammalian cell	Detail
GM-Tg-rg-IP0249-Ag	Rat	Rat SPTLC2 recombinant protein	Mammalian cell	Detail
GM-Tg-mg-IP0249-Ag	Mouse	Mouse SPTLC2 recombinant protein	Mammalian cell	Detail
GM-Tg-cynog-IP0249-Ag	Cynomolgus/Rhesus macaque	Cynomolgus/Rhesus macaque SPTLC2 recombinant protein	Mammalian cell	Detail
GM-Tg-felg-IP0249-Ag	Cat/Feline	Cat/Feline SPTLC2 recombinant protein	Mammalian cell	Detail
GM-Tg-cang-IP0249-Ag	Dog/Canine	Dog/Canine SPTLC2 recombinant protein	Mammalian cell	Detail
GM-Tg-bovg-IP0249-Ag	Bovines/Cattle	Bovines/Cattle SPTLC2 recombinant protein	Mammalian cell	Detail
GM-Tg-equg-IP0249-Ag	Equine/Horse	Equine/Horse SPTLC2 recombinant protein	Mammalian cell	Detail