Explore CaMKII/CAMK2B gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
premier destination for multi-species gene research solutions
Target
sublocation: Introcelluar Protein.
The product of this gene belongs to the serine/threonine protein kinase family and to the Ca(2+)/calmodulin-dependent protein kinase subfamily. Calcium signaling is crucial for several aspects of plasticity at glutamatergic synapses. In mammalian cells, the enzyme is composed of four different chains: alpha, beta, gamma, and delta. The product of this gene is a beta chain. It is possible that distinct isoforms of this chain have different cellular localizations and interact differently with calmodulin. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2014]
| Target ID |
GM-IP0246
|
| Target Name |
CaMKII/CAMK2B
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
816
|
| Gene ID |
100146368 (Equus caballus), 101098615 (Felis catus), 12323 (Mus musculus), 24245 (Rattus norvegicus)
482687 (Canis lupus familiaris), 525416 (Bos taurus), 706977 (Macaca mulatta), 816 (Homo sapiens)
|
| Target Alternative Names |
CAM2,CAMK2,CAMK2B,CAMKB,CaM kinase II subunit beta,CaMK-II subunit beta,CaMKII,CaMKIIbeta,Calcium/calmodulin-dependent protein kinase type II subunit beta,Camk2b,Ck2b,MRD54
|
| Uniprot Accession |
P28652,P08413,Q3MHJ9,Q13554
|
| Protein Sub-location |
Introcelluar Protein
|
| Category |
Therapeutics Target
|
| Disease from KEGG |
ErbB signaling pathway, Calcium signaling pathway, cAMP signaling pathway, HIF-1 signaling pathway, Adrenergic signaling in cardiomyocytes, Wnt signaling pathway, Axon guidance, Circadian entrainment, Long-term potentiation, Neurotrophin signaling pathway, Cholinergic synapse, Olfactory transduction, Inflammatory mediator regulation of TRP channels, Insulin secretion, GnRH signaling pathway, Melanogenesis, Oxytocin signaling pathway, Aldosterone synthesis and secretion, Cushing syndrome, Gastric acid secretion, Amphetamine addiction, Tuberculosis, Pathways in cancer, Proteoglycans in cancer, Glioma, Lipid and atherosclerosis
|
| Gene Ensembl |
ENSECAG00000017000, ENSMUSG00000057897, ENSCAFG00845012770, ENSBTAG00000012653, ENSMMUG00000002433, ENSG00000058404
|
| Target Classification |
Kinase
|
Pre-made viral vector of CaMKII/CAMK2B cDNA Clones/ORF Plasmid
CaMKII/CAMK2B siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo816 | Pre-made Human CAMK2B/CAM2/CAMK2 siRNA oligo Duplex | 816 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo24245 | Pre-made Rat Camk2b/Ck2b siRNA oligo Duplex | 24245 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo12323 | Pre-made Mouse Camk2b/CaMKII siRNA oligo Duplex | 12323 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo706977 | Pre-made Cynomolgus/Rhesus macaque CAMK2B siRNA oligo Duplex | 706977 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101098615 | Pre-made Cat/Feline CAMK2B siRNA oligo Duplex | 101098615 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo482687 | Pre-made Dog/Canine CAMK2B siRNA oligo Duplex | 482687 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo525416 | Pre-made Bovines/Cattle CAMK2B siRNA oligo Duplex | 525416 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100146368 | Pre-made Equine/Horse CAMK2B siRNA oligo Duplex | 100146368 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
CaMKII/CAMK2B antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-IP0246-Ab | Human | Anti-Human CaMKII/CAMK2B monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-rg-IP0246-Ab | Rat | Anti-Rat CaMKII/CAMK2B monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-mg-IP0246-Ab | Mouse | Anti-Mouse CaMKII/CAMK2B monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cynog-IP0246-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque CaMKII/CAMK2B monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-felg-IP0246-Ab | Cat/Feline | Anti-Cat/Feline CaMKII/CAMK2B monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cang-IP0246-Ab | Dog/Canine | Anti-Dog/Canine CaMKII/CAMK2B monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-bovg-IP0246-Ab | Bovines/Cattle | Anti-Bovines/Cattle CaMKII/CAMK2B monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-equg-IP0246-Ab | Equine/Horse | Anti-Equine/Horse CaMKII/CAMK2B monoclonal antibody | mab | Therapeutics Target antibody | Detail |
CaMKII/CAMK2B recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-IP0246-Ag | Human | Human CaMKII/CAMK2B recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-IP0246-Ag | Rat | Rat CaMKII/CAMK2B recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-IP0246-Ag | Mouse | Mouse CaMKII/CAMK2B recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-IP0246-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque CaMKII/CAMK2B recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-IP0246-Ag | Cat/Feline | Cat/Feline CaMKII/CAMK2B recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-IP0246-Ag | Dog/Canine | Dog/Canine CaMKII/CAMK2B recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-IP0246-Ag | Bovines/Cattle | Bovines/Cattle CaMKII/CAMK2B recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-IP0246-Ag | Equine/Horse | Equine/Horse CaMKII/CAMK2B recombinant protein | Mammalian cell | Detail |
