SOCS3 Target & Gene Products-cDNA ORF clones/siRNA/antibody/protein

Explore SOCS3 gene products and cross-species research data at TarMart platform. Discover comprehensive biological information, expression tools, and therapeutic insights for Homo sapiens (human), Cynomolgus monkeys, rodents (mouse/rat), canines, felines, bovines, and equines. Your premier destination for multi-species gene research solutions
Target sublocation: Introcelluar Protein.
This gene encodes a member of the STAT-induced STAT inhibitor (SSI), also known as suppressor of cytokine signaling (SOCS), family. SSI family members are cytokine-inducible negative regulators of cytokine signaling. The expression of this gene is induced by various cytokines, including IL6, IL10, and interferon (IFN)-gamma. The protein encoded by this gene can bind to JAK2 kinase, and inhibit the activity of JAK2 kinase. Studies of the mouse counterpart of this gene suggested the roles of this gene in the negative regulation of fetal liver hematopoiesis, and placental development. [provided by RefSeq, Jul 2008]

Target ID GM-IP0224
Target Name SOCS3
Gene Group ldentifer
（Target Gene ID in Homo species) 		9021
Gene ID 100050730 (Equus caballus), 101081846 (Felis catus), 12702 (Mus musculus), 282081 (Bos taurus)
442949 (Canis lupus familiaris), 715680 (Macaca mulatta), 89829 (Rattus norvegicus), 9021 (Homo sapiens)
Target Alternative Names ATOD4,CIS3,Cis3,Cish3,Cytokine-inducible SH2 protein 3 (CIS-3),EF-10,Ef10,SOCS-3,SOCS3,SSI-3,SSI3,STAT-induced STAT inhibitor 3 (SSI-3),Socs-3,Socs3,Ssi-3,Ssi3,Suppressor of cytokine signaling 3
Uniprot Accession O35718,Q9BEG9,Q68AM8,O88583,O14543
Protein Sub-location Introcelluar Protein
Disease cancer, Prostate Cancer
Disease from KEGG Osteoclast differentiation, JAK-STAT signaling pathway, TNF signaling pathway, Prolactin signaling pathway, Adipocytokine signaling pathway, Type II diabetes mellitus, Insulin resistance, Growth hormone synthesis, secretion and action, Hepatitis C, Influenza A
Gene Ensembl ENSECAG00000001249, ENSMUSG00000053113, ENSBTAG00000008441, ENSCAFG00845014621, ENSMMUG00000058428, ENSG00000184557


Pre-made viral vector of SOCS3 cDNA Clones/ORF Plasmid

Cat No.Product NameNMIDGeneIDSpeciesTypeMarkerFusion TagPromoterDetail
pGMLP001904Human SOCS3/ATOD4/CIS3 Lentivirus plasmidNM_003955.4 9021HumanLentivirus plasmidZsGreen3xflag (C-Terminal)CMVDetail
vGMLP001904Human SOCS3/ATOD4/CIS3 Lentivirus particleNM_003955.4 9021HumanLentivirus particleZsGreen3xflag (C-Terminal)CMVDetail
pGMLV001121Mouse Socs3/CI/Cis Lentivirus plasmidNM_007707.312702MouseLentivirus plasmidNull3xflag (C-Terminal)CMVDetail
pGMAD000906Mouse Socs3/CI/Cis Adenovirus plasmidNM_007707.312702MouseAdenovirus plasmidEGFP3xflag (C-Terminal)EF1Detail
pGMLPm001906Mouse Socs3/Cis3/Cish3 Lentivirus plasmidNM_00770712702MouseLentivirus plasmidZsGreen3xflag (C-Terminal)CMVDetail
vGMLV001121Mouse Socs3/CI/Cis Lentivirus particleNM_007707.312702MouseLentivirus particleNull3xflag (C-Terminal)CMVDetail
vGMAD000906Mouse Socs3/CI/Cis Adenovirus particleNM_007707.312702MouseAdenovirus particleEGFP3xflag (C-Terminal)EF1Detail
vGMLPm001906Mouse Socs3/Cis3/Cish3 Lentivirus particleNM_00770712702MouseLentivirus particleZsGreen3xflag (C-Terminal)CMVDetail
pGMAD000390Cattle SOCS3/SSI-3 Adenovirus plasmidNM_174466.2282081CattleAdenovirus plasmidGFP3xflag (C-Terminal)EF1Detail
vGMAD000390Cattle SOCS3/SSI-3 Adenovirus particleNM_174466.2282081CattleAdenovirus particleGFP3xflag (C-Terminal)EF1Detail


SOCS3 siRNA/miRNA/oligo for RNA interfence (RNAi)

Cat No.Product NameGeneIDSpeciesGradeDetail
pGMoligo9021Pre-made Human SOCS3/CIS3/SSI3 siRNA oligo Duplex9021HumanIn-vitro grade; in-vivo gradeDetail
pGMoligo89829Pre-made Rat Socs3/Cish3/Ssi-3 siRNA oligo Duplex89829RatIn-vitro grade; in-vivo gradeDetail
pGMoligo12702Pre-made Mouse Socs3/Cis3/Ef10 siRNA oligo Duplex12702MouseIn-vitro grade; in-vivo gradeDetail
pGMoligo715680Pre-made Cynomolgus/Rhesus macaque SOCS3 siRNA oligo Duplex715680Cynomolgus/Rhesus macaqueIn-vitro grade; in-vivo gradeDetail
pGMoligo101081846Pre-made Cat/Feline SOCS3 siRNA oligo Duplex101081846Cat/FelineIn-vitro grade; in-vivo gradeDetail
pGMoligo442949Pre-made Dog/Canine SOCS3/SOCS-3 siRNA oligo Duplex442949Dog/CanineIn-vitro grade; in-vivo gradeDetail
pGMoligo282081Pre-made Bovines/Cattle SOCS3/SSI-3 siRNA oligo Duplex282081Bovines/CattleIn-vitro grade; in-vivo gradeDetail
pGMoligo100050730Pre-made Equine/Horse SOCS3 siRNA oligo Duplex100050730Equine/HorseIn-vitro grade; in-vivo gradeDetail


SOCS3 antibody/GMab

Cat No.SpeciesAntibody NameFormatClassified by tagDetail
GM-Tg-hg-IP0224-AbHumanAnti-Human SOCS3 monoclonal antibodymabDetail
GM-Tg-rg-IP0224-AbRatAnti-Rat SOCS3 monoclonal antibodymabDetail
GM-Tg-mg-IP0224-AbMouseAnti-Mouse SOCS3 monoclonal antibodymabDetail
GM-Tg-cynog-IP0224-AbCynomolgus/Rhesus macaqueAnti-Cynomolgus/Rhesus macaque SOCS3 monoclonal antibodymabDetail
GM-Tg-felg-IP0224-AbCat/FelineAnti-Cat/Feline SOCS3 monoclonal antibodymabDetail
GM-Tg-cang-IP0224-AbDog/CanineAnti-Dog/Canine SOCS3 monoclonal antibodymabDetail
GM-Tg-bovg-IP0224-AbBovines/CattleAnti-Bovines/Cattle SOCS3 monoclonal antibodymabDetail
GM-Tg-equg-IP0224-AbEquine/HorseAnti-Equine/Horse SOCS3 monoclonal antibodymabDetail


SOCS3 recombinant protein

Cat No.SpeciesAntigen NameExpression PlatformDetail
GM-Tg-hg-IP0224-AgHumanHuman SOCS3 recombinant proteinMammalian cellDetail
GM-Tg-rg-IP0224-AgRatRat SOCS3 recombinant proteinMammalian cellDetail
GM-Tg-mg-IP0224-AgMouseMouse SOCS3 recombinant proteinMammalian cellDetail
GM-Tg-cynog-IP0224-AgCynomolgus/Rhesus macaqueCynomolgus/Rhesus macaque SOCS3 recombinant proteinMammalian cellDetail
GM-Tg-felg-IP0224-AgCat/FelineCat/Feline SOCS3 recombinant proteinMammalian cellDetail
GM-Tg-cang-IP0224-AgDog/CanineDog/Canine SOCS3 recombinant proteinMammalian cellDetail
GM-Tg-bovg-IP0224-AgBovines/CattleBovines/Cattle SOCS3 recombinant proteinMammalian cellDetail
GM-Tg-equg-IP0224-AgEquine/HorseEquine/Horse SOCS3 recombinant proteinMammalian cellDetail