Explore MRC2/CD280 gene products and cross-species
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biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Introcelluar Protein.
This gene encodes a member of the mannose receptor family of proteins that contain a fibronectin type II domain and multiple C-type lectin-like domains. The encoded protein plays a role in extracellular matrix remodeling by mediating the internalization and lysosomal degradation of collagen ligands. Expression of this gene may play a role in the tumorigenesis and metastasis of several malignancies including breast cancer, gliomas and metastatic bone disease. [provided by RefSeq, Feb 2012]
| Target ID |
GM-IP0222
|
| Target Name |
MRC2/CD280
|
Gene Group ldentifer (Target Gene ID in Homo
species)
|
9902
|
| Gene ID |
100064998 (Equus caballus), 100688560 (Canis lupus familiaris), 101082106 (Felis catus), 17534 (Mus musculus) 498011 (Rattus norvegicus), 529049 (Bos taurus), 717576 (Macaca mulatta), 9902 (Homo sapiens)
|
| Target Alternative Names |
C-type lectin domain family 13 member E,C-type mannose receptor 2,CD280,CLEC13E,ENDO180,Endo180,Endocytic receptor 180,MRC2,Macrophage mannose receptor 2,Mrc2,UPARAP,Urokinase receptor-associated protein),Urokinase-type plasminogen activator receptor-associated protein (UPAR-associated protein,mKIAA0709,uPARAP
|
| Uniprot Accession |
Q64449,Q4TU93,Q9UBG0
|
| Protein Sub-location |
Introcelluar Protein
|
| Disease from KEGG |
Phagosome, Tuberculosis
|
| Gene Ensembl |
ENSECAG00000012627, ENSCAFG00845016995, ENSMUSG00000020695, ENSBTAG00000015739, ENSMMUG00000002167, ENSG00000011028
|
MRC2/CD280 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo9902 | Pre-made Human MRC2/CD280/UPARAP siRNA oligo Duplex | 9902 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo498011 | Pre-made Rat Mrc2/Endo180 siRNA oligo Duplex | 498011 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo17534 | Pre-made Mouse Mrc2/uPARAP/Endo180 siRNA oligo Duplex | 17534 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo717576 | Pre-made Cynomolgus/Rhesus macaque MRC2 siRNA oligo Duplex | 717576 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101082106 | Pre-made Cat/Feline MRC2 siRNA oligo Duplex | 101082106 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100688560 | Pre-made Dog/Canine MRC2 siRNA oligo Duplex | 100688560 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo529049 | Pre-made Bovines/Cattle MRC2 siRNA oligo Duplex | 529049 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100064998 | Pre-made Equine/Horse MRC2 siRNA oligo Duplex | 100064998 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
MRC2/CD280 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-IP0222-Ab | Human | Anti-Human MRC2/CD280 monoclonal antibody | mab | | Detail |
| GM-Tg-rg-IP0222-Ab | Rat | Anti-Rat MRC2/CD280 monoclonal antibody | mab | | Detail |
| GM-Tg-mg-IP0222-Ab | Mouse | Anti-Mouse MRC2/CD280 monoclonal antibody | mab | | Detail |
| GM-Tg-cynog-IP0222-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque MRC2/CD280 monoclonal antibody | mab | | Detail |
| GM-Tg-felg-IP0222-Ab | Cat/Feline | Anti-Cat/Feline MRC2/CD280 monoclonal antibody | mab | | Detail |
| GM-Tg-cang-IP0222-Ab | Dog/Canine | Anti-Dog/Canine MRC2/CD280 monoclonal antibody | mab | | Detail |
| GM-Tg-bovg-IP0222-Ab | Bovines/Cattle | Anti-Bovines/Cattle MRC2/CD280 monoclonal antibody | mab | | Detail |
| GM-Tg-equg-IP0222-Ab | Equine/Horse | Anti-Equine/Horse MRC2/CD280 monoclonal antibody | mab | | Detail |
MRC2/CD280 recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-IP0222-Ag | Human | Human MRC2/CD280 recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-IP0222-Ag | Rat | Rat MRC2/CD280 recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-IP0222-Ag | Mouse | Mouse MRC2/CD280 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-IP0222-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque MRC2/CD280 recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-IP0222-Ag | Cat/Feline | Cat/Feline MRC2/CD280 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-IP0222-Ag | Dog/Canine | Dog/Canine MRC2/CD280 recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-IP0222-Ag | Bovines/Cattle | Bovines/Cattle MRC2/CD280 recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-IP0222-Ag | Equine/Horse | Equine/Horse MRC2/CD280 recombinant protein | Mammalian cell | Detail |