PTBP1 Target & Gene Products-cDNA ORF clones/siRNA/antibody/protein

Explore PTBP1 gene products and cross-species research data at TarMart platform. Discover comprehensive biological information, expression tools, and therapeutic insights for Homo sapiens (human), Cynomolgus monkeys, rodents (mouse/rat), canines, felines, bovines, and equines. Your premier destination for multi-species gene research solutions
Target sublocation: Introcelluar Protein.
This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA-binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has four repeats of quasi-RNA recognition motif (RRM) domains that bind RNAs. This protein binds to the intronic polypyrimidine tracts that requires pre-mRNA splicing and acts via the protein degradation ubiquitin-proteasome pathway. It may also promote the binding of U2 snRNP to pre-mRNAs. This protein is localized in the nucleoplasm and it is also detected in the perinucleolar structure. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008]

Target ID GM-IP0177
Target Name PTBP1
Gene Group ldentifer
(Target Gene ID in Homo species)
5725
Gene ID 100061673 (Equus caballus), 101092744 (Felis catus), 19205 (Mus musculus), 282018 (Bos taurus)
29497 (Rattus norvegicus), 485097 (Canis lupus familiaris), 5725 (Homo sapiens), 703430 (Macaca mulatta)
Target Alternative Names 57 kDa RNA-binding protein PPTB-1,HNRNP-I,HNRNPI,HNRPI,Heterogeneous nuclear ribonucleoprotein I (hnRNP I),PTB,PTB-1,PTB-T,PTB1,PTB2,PTB3,PTB4,PTBP1,Polypyrimidine tract-binding protein 1,Ptb,Ptbp1,Pybp,Pybp1,Pybp2,pPTB
Uniprot Accession P17225,Q8WN55,Q00438,P26599
Protein Sub-location Introcelluar Protein
Category Therapeutics Target
Gene Ensembl ENSECAG00000018845, ENSMUSG00000006498, ENSBTAG00000045828, ENSCAFG00845014619, ENSG00000011304, ENSMMUG00000016450


Pre-made viral vector of PTBP1 cDNA Clones/ORF Plasmid

Cat No.Product NameNMIDGeneIDSpeciesTypeMarkerFusion TagPromoterDetail
pGMLP001418Human PTBP1/HNRNP-I/HNRNPI Lentivirus plasmidNM_0028195725HumanLentivirus plasmidZsGreen3xflag (C-Terminal)CMVDetail
vGMLP001418Human PTBP1/HNRNP-I/HNRNPI Lentivirus particleNM_0028195725HumanLentivirus particleZsGreen3xflag (C-Terminal)CMVDetail
pGMLV001483Mouse Ptbp1/AA407203/AL033359 Lentivirus plasmidNM_001077363.219205MouseLentivirus plasmidZsGreen3xflag (C-Terminal)CMVDetail
pGMAAV001685Mouse Ptbp1/HNRPI/pPTB Adeno-associate virus(AAV) plasmidNM_00107736319205MouseAdeno-associate virus(AAV) plasmidmCherry3xflag (C-Terminal)MYOGDetail
pGMAAV001921Mouse Ptbp1/AA407203/AL033359 Adeno-associate virus(AAV) plasmidNM_001077363.219205MouseAdeno-associate virus(AAV) plasmidEGFP3xflag (C-Terminal)GFAPDetail
pGMLPm003948Mouse Ptbp1/AA407203/AL033359 Lentivirus plasmidNM_00107736319205MouseLentivirus plasmidZsGreen3xflag (C-Terminal)CMVDetail
vGMLV001483Mouse Ptbp1/AA407203/AL033359 Lentivirus particleNM_001077363.219205MouseLentivirus particleZsGreen3xflag (C-Terminal)CMVDetail
vGMAAV001685Mouse Ptbp1/HNRPI/pPTB Adeno-associate virus(AAV) particleNM_00107736319205MouseAdeno-associate virus(AAV) particlemCherry3xflag (C-Terminal)MYOGDetail
vGMAAV001921Mouse Ptbp1/AA407203/AL033359 Adeno-associate virus(AAV) particleNM_001077363.219205MouseAdeno-associate virus(AAV) particleEGFP3xflag (C-Terminal)GFAPDetail
vGMLPm003948Mouse Ptbp1/AA407203/AL033359 Lentivirus particleNM_00107736319205MouseLentivirus particleZsGreen3xflag (C-Terminal)CMVDetail


PTBP1 siRNA/miRNA/oligo for RNA interfence (RNAi)

Cat No.Product NameGeneIDSpeciesGradeDetail
pGMoligo5725Pre-made Human PTBP1/PTB/PTB2 siRNA oligo Duplex5725HumanIn-vitro grade; in-vivo gradeDetail
pGMoligo29497Pre-made Rat Ptbp1/Ptb/PTB1 siRNA oligo Duplex29497RatIn-vitro grade; in-vivo gradeDetail
pGMoligo19205Pre-made Mouse Ptbp1/Ptb/PTB2 siRNA oligo Duplex19205MouseIn-vitro grade; in-vivo gradeDetail
pGMoligo703430Pre-made Cynomolgus/Rhesus macaque PTBP1 siRNA oligo Duplex703430Cynomolgus/Rhesus macaqueIn-vitro grade; in-vivo gradeDetail
pGMoligo101092744Pre-made Cat/Feline PTBP1 siRNA oligo Duplex101092744Cat/FelineIn-vitro grade; in-vivo gradeDetail
pGMoligo485097Pre-made Dog/Canine PTBP1 siRNA oligo Duplex485097Dog/CanineIn-vitro grade; in-vivo gradeDetail
pGMoligo282018Pre-made Bovines/Cattle PTBP1/PTB siRNA oligo Duplex282018Bovines/CattleIn-vitro grade; in-vivo gradeDetail
pGMoligo100061673Pre-made Equine/Horse PTBP1 siRNA oligo Duplex100061673Equine/HorseIn-vitro grade; in-vivo gradeDetail


PTBP1 antibody/GMab

Cat No.SpeciesAntibody NameFormatClassified by tagDetail
GM-Tg-hg-IP0177-AbHumanAnti-Human PTBP1 monoclonal antibodymabTherapeutics Target antibodyDetail
GM-Tg-rg-IP0177-AbRatAnti-Rat PTBP1 monoclonal antibodymabTherapeutics Target antibodyDetail
GM-Tg-mg-IP0177-AbMouseAnti-Mouse PTBP1 monoclonal antibodymabTherapeutics Target antibodyDetail
GM-Tg-cynog-IP0177-AbCynomolgus/Rhesus macaqueAnti-Cynomolgus/Rhesus macaque PTBP1 monoclonal antibodymabTherapeutics Target antibodyDetail
GM-Tg-felg-IP0177-AbCat/FelineAnti-Cat/Feline PTBP1 monoclonal antibodymabTherapeutics Target antibodyDetail
GM-Tg-cang-IP0177-AbDog/CanineAnti-Dog/Canine PTBP1 monoclonal antibodymabTherapeutics Target antibodyDetail
GM-Tg-bovg-IP0177-AbBovines/CattleAnti-Bovines/Cattle PTBP1 monoclonal antibodymabTherapeutics Target antibodyDetail
GM-Tg-equg-IP0177-AbEquine/HorseAnti-Equine/Horse PTBP1 monoclonal antibodymabTherapeutics Target antibodyDetail


PTBP1 recombinant protein

Cat No.SpeciesAntigen NameExpression PlatformDetail
GM-Tg-hg-IP0177-AgHumanHuman PTBP1 recombinant proteinMammalian cellDetail
GM-Tg-rg-IP0177-AgRatRat PTBP1 recombinant proteinMammalian cellDetail
GM-Tg-mg-IP0177-AgMouseMouse PTBP1 recombinant proteinMammalian cellDetail
GM-Tg-cynog-IP0177-AgCynomolgus/Rhesus macaqueCynomolgus/Rhesus macaque PTBP1 recombinant proteinMammalian cellDetail
GM-Tg-felg-IP0177-AgCat/FelineCat/Feline PTBP1 recombinant proteinMammalian cellDetail
GM-Tg-cang-IP0177-AgDog/CanineDog/Canine PTBP1 recombinant proteinMammalian cellDetail
GM-Tg-bovg-IP0177-AgBovines/CattleBovines/Cattle PTBP1 recombinant proteinMammalian cellDetail
GM-Tg-equg-IP0177-AgEquine/HorseEquine/Horse PTBP1 recombinant proteinMammalian cellDetail