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insights for Homo sapiens (human), Cynomolgus monkeys, rodents
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Target
sublocation: Introcelluar Protein.
There are believed to be over 100 different glycosyltransferases involved in the synthesis of protein-bound and lipid-bound oligosaccharides. UDP-N-acetylglucosamine:alpha-3-D-mannoside beta-1,2-N-acetylglucosaminyltransferase I is a medial-Golgi enzyme essential for the synthesis of hybrid and complex N-glycans. The protein, encoded by a single exon, shows typical features of a type II transmembrane protein. The protein is believed to be essential for normal embryogenesis. Several variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]
| Target ID |
GM-IP0176
|
| Target Name |
MGAT1/NAGAT1
|
Gene Group ldentifer (Target Gene ID in Homo
species)
|
4245
|
| Gene ID |
101082035 (Felis catus), 102149649 (Equus caballus), 17308 (Mus musculus), 4245 (Homo sapiens) 534248 (Bos taurus), 707375 (Macaca mulatta), 81519 (Rattus norvegicus)
|
| Target Alternative Names |
3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase,Alpha-1,GLCNAC-TI,GLCT1,GLYT1,GNT-1,GNT-I,GlcNAc-T I),GnTI,MGAT,MGAT1,Mgat-1,Mgat1,N-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase I (GNT-I,NAGAT1
|
| Uniprot Accession |
P27808,P26572,Q09325
|
| Protein Sub-location |
Introcelluar Protein
|
| Category |
Therapeutics Target
|
| Disease from KEGG |
Metabolic pathways, N-Glycan biosynthesis, Various types of N-glycan biosynthesis
|
| Gene Ensembl |
ENSECAG00000014786, ENSMUSG00000020346, ENSG00000131446, ENSBTAG00000001546, ENSMMUG00000047880
|
Pre-made viral vector of MGAT1/NAGAT1 cDNA Clones/ORF Plasmid
MGAT1/NAGAT1 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo4245 | Pre-made Human MGAT1/GnTI/MGAT siRNA oligo Duplex | 4245 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo81519 | Pre-made Rat Mgat1 siRNA oligo Duplex | 81519 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo17308 | Pre-made Mouse Mgat1/Mgat-1 siRNA oligo Duplex | 17308 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo707375 | Pre-made Cynomolgus/Rhesus macaque MGAT1 siRNA oligo Duplex | 707375 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101082035 | Pre-made Cat/Feline MGAT1 siRNA oligo Duplex | 101082035 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo534248 | Pre-made Bovines/Cattle MGAT1/GNT-1 siRNA oligo Duplex | 534248 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo102149649 | Pre-made Equine/Horse MGAT1 siRNA oligo Duplex | 102149649 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
MGAT1/NAGAT1 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-IP0176-Ab | Human | Anti-Human MGAT1/NAGAT1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-rg-IP0176-Ab | Rat | Anti-Rat MGAT1/NAGAT1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-mg-IP0176-Ab | Mouse | Anti-Mouse MGAT1/NAGAT1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cynog-IP0176-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque MGAT1/NAGAT1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-felg-IP0176-Ab | Cat/Feline | Anti-Cat/Feline MGAT1/NAGAT1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-bovg-IP0176-Ab | Bovines/Cattle | Anti-Bovines/Cattle MGAT1/NAGAT1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-equg-IP0176-Ab | Equine/Horse | Anti-Equine/Horse MGAT1/NAGAT1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
MGAT1/NAGAT1 recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-IP0176-Ag | Human | Human MGAT1/NAGAT1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-IP0176-Ag | Rat | Rat MGAT1/NAGAT1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-IP0176-Ag | Mouse | Mouse MGAT1/NAGAT1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-IP0176-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque MGAT1/NAGAT1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-IP0176-Ag | Cat/Feline | Cat/Feline MGAT1/NAGAT1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-IP0176-Ag | Bovines/Cattle | Bovines/Cattle MGAT1/NAGAT1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-IP0176-Ag | Equine/Horse | Equine/Horse MGAT1/NAGAT1 recombinant protein | Mammalian cell | Detail |