Explore G6PC2 gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
premier destination for multi-species gene research solutions
Target
sublocation: Introcelluar Protein.
This gene encodes an enzyme belonging to the glucose-6-phosphatase catalytic subunit family. These enzymes are part of a multicomponent integral membrane system that catalyzes the hydrolysis of glucose-6-phosphate, the terminal step in gluconeogenic and glycogenolytic pathways, allowing the release of glucose into the bloodstream. The family member encoded by this gene is found in pancreatic islets and does not exhibit phosphohydrolase activity, but it is a major target of cell-mediated autoimmunity in diabetes. Several alternatively spliced transcript variants of this gene have been described, but their biological validity has not been determined. [provided by RefSeq, Jul 2008]
| Target ID |
GM-IP0165
|
| Target Name |
G6PC2
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
57818
|
| Gene ID |
100062750 (Equus caballus), 101085486 (Felis catus), 14378 (Mus musculus), 488389 (Canis lupus familiaris)
505012 (Bos taurus), 57818 (Homo sapiens), 681817 (Rattus norvegicus), 709062 (Macaca mulatta)
|
| Target Alternative Names |
G-6-Pase 2,G6PC2,G6Pase 2,G6pc-rs,G6pc2,Glucose-6-phosphatase 2,IGRP,Igrp,Islet-specific glucose-6-phosphatase catalytic subunit-related protein
|
| Uniprot Accession |
Q9Z186,Q9NQR9
|
| Protein Sub-location |
Introcelluar Protein
|
| Category |
Therapeutics Target
|
| Disease from KEGG |
Metabolic pathways, FoxO signaling pathway, PI3K-Akt signaling pathway, Adipocytokine signaling pathway, Insulin resistance, Carbohydrate digestion and absorption
|
| Gene Ensembl |
ENSECAG00000010214, ENSMUSG00000005232, ENSCAFG00845020499, ENSBTAG00000004241, ENSG00000152254, ENSMMUG00000013830
|
G6PC2 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo57818 | Pre-made Human G6PC2/IGRP siRNA oligo Duplex | 57818 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo681817 | Pre-made Rat G6pc2/Igrp/G6pc-rs siRNA oligo Duplex | 681817 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo14378 | Pre-made Mouse G6pc2/IGRP/G6pc-rs siRNA oligo Duplex | 14378 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo709062 | Pre-made Cynomolgus/Rhesus macaque G6PC2 siRNA oligo Duplex | 709062 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101085486 | Pre-made Cat/Feline G6PC2 siRNA oligo Duplex | 101085486 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo488389 | Pre-made Dog/Canine G6PC2 siRNA oligo Duplex | 488389 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo505012 | Pre-made Bovines/Cattle G6PC2 siRNA oligo Duplex | 505012 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100062750 | Pre-made Equine/Horse G6PC2 siRNA oligo Duplex | 100062750 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
G6PC2 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-IP0165-Ab | Human | Anti-Human G6PC2 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-rg-IP0165-Ab | Rat | Anti-Rat G6PC2 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-mg-IP0165-Ab | Mouse | Anti-Mouse G6PC2 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cynog-IP0165-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque G6PC2 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-felg-IP0165-Ab | Cat/Feline | Anti-Cat/Feline G6PC2 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cang-IP0165-Ab | Dog/Canine | Anti-Dog/Canine G6PC2 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-bovg-IP0165-Ab | Bovines/Cattle | Anti-Bovines/Cattle G6PC2 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-equg-IP0165-Ab | Equine/Horse | Anti-Equine/Horse G6PC2 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
G6PC2 recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-IP0165-Ag | Human | Human G6PC2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-IP0165-Ag | Rat | Rat G6PC2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-IP0165-Ag | Mouse | Mouse G6PC2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-IP0165-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque G6PC2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-IP0165-Ag | Cat/Feline | Cat/Feline G6PC2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-IP0165-Ag | Dog/Canine | Dog/Canine G6PC2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-IP0165-Ag | Bovines/Cattle | Bovines/Cattle G6PC2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-IP0165-Ag | Equine/Horse | Equine/Horse G6PC2 recombinant protein | Mammalian cell | Detail |
