Explore TXNIP/VDUP1 gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
premier destination for multi-species gene research solutions
Target
sublocation: Introcelluar Protein.
This gene encodes a thioredoxin-binding protein that is a member of the alpha arrestin protein family. Thioredoxin is a thiol-oxidoreductase that is a major regulator of cellular redox signaling which protects cells from oxidative stress. This protein inhibits the antioxidative function of thioredoxin resulting in the accumulation of reactive oxygen species and cellular stress. This protein also functions as a regulator of cellular metabolism and of endoplasmic reticulum (ER) stress. This protein may also function as a tumor suppressor. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2015]
| Target ID |
GM-IP0163
|
| Target Name |
TXNIP/VDUP1
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
10628
|
| Gene ID |
101099739 (Felis catus), 10628 (Homo sapiens), 111773538 (Equus caballus), 117514 (Rattus norvegicus)
475829 (Canis lupus familiaris), 506790 (Bos taurus), 56338 (Mus musculus), 698683 (Macaca mulatta)
|
| Target Alternative Names |
1200008J08Rik,ARRDC6,EST01027,HHCPA78,Hyplip1,THIF,TXNIP,Tbp-2,Thioredoxin-binding protein 2,Thioredoxin-interacting protein,Txnip,VDUP1,Vdup1,Vitamin D3 up-regulated protein 1
|
| Uniprot Accession |
Q9H3M7,Q5M7W1,Q8BG60
|
| Protein Sub-location |
Introcelluar Protein
|
| Category |
Therapeutics Target
|
| Disease |
cancer
|
| Disease from KEGG |
NOD-like receptor signaling pathway
|
| Gene Ensembl |
ENSG00000265972, ENSECAG00000028144, ENSCAFG00845011435, ENSBTAG00000020060, ENSMUSG00000038393, ENSMMUG00000007338
|
| Target Classification |
Tumor-associated antigen (TAA)
|
Pre-made viral vector of TXNIP/VDUP1 cDNA Clones/ORF Plasmid
TXNIP/VDUP1 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo10628 | Pre-made Human TXNIP/THIF/VDUP1 siRNA oligo Duplex | 10628 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo117514 | Pre-made Rat Txnip/Vdup1 siRNA oligo Duplex | 117514 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo56338 | Pre-made Mouse Txnip/THIF/Tbp-2 siRNA oligo Duplex | 56338 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo698683 | Pre-made Cynomolgus/Rhesus macaque TXNIP siRNA oligo Duplex | 698683 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101099739 | Pre-made Cat/Feline TXNIP siRNA oligo Duplex | 101099739 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo475829 | Pre-made Dog/Canine TXNIP siRNA oligo Duplex | 475829 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo506790 | Pre-made Bovines/Cattle TXNIP siRNA oligo Duplex | 506790 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo111773538 | Pre-made Equine/Horse TXNIP siRNA oligo Duplex | 111773538 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
TXNIP/VDUP1 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-IP0163-Ab | Human | Anti-Human TXNIP/VDUP1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-rg-IP0163-Ab | Rat | Anti-Rat TXNIP/VDUP1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-mg-IP0163-Ab | Mouse | Anti-Mouse TXNIP/VDUP1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cynog-IP0163-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque TXNIP/VDUP1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-felg-IP0163-Ab | Cat/Feline | Anti-Cat/Feline TXNIP/VDUP1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cang-IP0163-Ab | Dog/Canine | Anti-Dog/Canine TXNIP/VDUP1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-bovg-IP0163-Ab | Bovines/Cattle | Anti-Bovines/Cattle TXNIP/VDUP1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-equg-IP0163-Ab | Equine/Horse | Anti-Equine/Horse TXNIP/VDUP1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
TXNIP/VDUP1 recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-IP0163-Ag | Human | Human TXNIP/VDUP1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-IP0163-Ag | Rat | Rat TXNIP/VDUP1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-IP0163-Ag | Mouse | Mouse TXNIP/VDUP1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-IP0163-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque TXNIP/VDUP1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-IP0163-Ag | Cat/Feline | Cat/Feline TXNIP/VDUP1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-IP0163-Ag | Dog/Canine | Dog/Canine TXNIP/VDUP1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-IP0163-Ag | Bovines/Cattle | Bovines/Cattle TXNIP/VDUP1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-IP0163-Ag | Equine/Horse | Equine/Horse TXNIP/VDUP1 recombinant protein | Mammalian cell | Detail |
