Explore PNPLA6 gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
premier destination for multi-species gene research solutions
Target
sublocation: Introcelluar Protein.
This gene encodes a phospholipase that deacetylates intracellular phosphatidylcholine to produce glycerophosphocholine. It is thought to function in neurite outgrowth and process elongation during neuronal differentiation. The protein is anchored to the cytoplasmic face of the endoplasmic reticulum in both neurons and non-neuronal cells. Mutations in this gene result in autosomal recessive spastic paraplegia, and the protein is the target for neurodegeneration induced by organophosphorus compounds and chemical warfare agents. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2009]
| Target ID |
GM-IP0156
|
| Target Name |
PNPLA6
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
10908
|
| Gene ID |
100060640 (Equus caballus), 100426338 (Macaca mulatta), 101097705 (Felis catus), 10908 (Homo sapiens)
360753 (Rattus norvegicus), 484993 (Canis lupus familiaris), 50767 (Mus musculus), 767822 (Bos taurus)
|
| Target Alternative Names |
BNHS,LNMS,MSws,NTE,NTEMND,Neuropathy target esterase,Nte,OMCS,PNPLA6,Patatin-like phospholipase domain-containing protein 6,Pnpla6,RGD1564611,SPG39,iPLA2delta,sws
|
| Uniprot Accession |
Q8IY17,Q3TRM4
|
| Protein Sub-location |
Introcelluar Protein
|
| Category |
Therapeutics Target
|
| Disease from KEGG |
Glycerophospholipid metabolism
|
| Gene Ensembl |
ENSECAG00000012712, ENSMMUG00000011392, ENSG00000032444, ENSCAFG00845025938, ENSMUSG00000004565, ENSBTAG00000032137
|
PNPLA6 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo10908 | Pre-made Human PNPLA6/NTE/sws siRNA oligo Duplex | 10908 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo360753 | Pre-made Rat Pnpla6/RGD1564611 siRNA oligo Duplex | 360753 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo50767 | Pre-made Mouse Pnpla6/Nte/MSws siRNA oligo Duplex | 50767 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100426338 | Pre-made Cynomolgus/Rhesus macaque PNPLA6 siRNA oligo Duplex | 100426338 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101097705 | Pre-made Cat/Feline PNPLA6 siRNA oligo Duplex | 101097705 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo484993 | Pre-made Dog/Canine PNPLA6 siRNA oligo Duplex | 484993 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo767822 | Pre-made Bovines/Cattle PNPLA6 siRNA oligo Duplex | 767822 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100060640 | Pre-made Equine/Horse PNPLA6 siRNA oligo Duplex | 100060640 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
PNPLA6 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-IP0156-Ab | Human | Anti-Human PNPLA6 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-rg-IP0156-Ab | Rat | Anti-Rat PNPLA6 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-mg-IP0156-Ab | Mouse | Anti-Mouse PNPLA6 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cynog-IP0156-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque PNPLA6 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-felg-IP0156-Ab | Cat/Feline | Anti-Cat/Feline PNPLA6 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cang-IP0156-Ab | Dog/Canine | Anti-Dog/Canine PNPLA6 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-bovg-IP0156-Ab | Bovines/Cattle | Anti-Bovines/Cattle PNPLA6 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-equg-IP0156-Ab | Equine/Horse | Anti-Equine/Horse PNPLA6 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
PNPLA6 recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-IP0156-Ag | Human | Human PNPLA6 recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-IP0156-Ag | Rat | Rat PNPLA6 recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-IP0156-Ag | Mouse | Mouse PNPLA6 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-IP0156-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque PNPLA6 recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-IP0156-Ag | Cat/Feline | Cat/Feline PNPLA6 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-IP0156-Ag | Dog/Canine | Dog/Canine PNPLA6 recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-IP0156-Ag | Bovines/Cattle | Bovines/Cattle PNPLA6 recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-IP0156-Ag | Equine/Horse | Equine/Horse PNPLA6 recombinant protein | Mammalian cell | Detail |
