Explore B7‑H4/B7-H4/VTCN1 gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Introcelluar Protein.
This gene encodes a protein belonging to the B7 costimulatory protein family. Proteins in this family are present on the surface of antigen-presenting cells and interact with ligand bound to receptors on the surface of T cells. Studies have shown that high levels of the encoded protein has been correlated with tumor progression. A pseudogene of this gene is located on chromosome 20. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2011]
| Target ID |
GM-IP0154
|
| Target Name |
B7‑H4/B7-H4/VTCN1
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
79679
|
| Gene ID |
100066328 (Equus caballus), 101086586 (Felis catus), 242122 (Mus musculus), 295322 (Rattus norvegicus)
483140 (Canis lupus familiaris), 539919 (Bos taurus), 714123 (Macaca mulatta), 79679 (Homo sapiens)
|
| Target Alternative Names |
VTCN1,Vtcn1,B7x,B7h4,B7s1,RGD1311204,B7X,B7H4,B7S1,B7-H4,B7h.5,VCTN1,PRO1291
|
| Uniprot Accession |
Q7TSP5,Q501W4,Q7Z7D3
|
| Uniprot Entry Name |
|
| Protein Sub-location |
Introcelluar Protein
|
| Category |
Therapeutics Target, Immuno-oncology Target, INN Index
|
| Disease |
Ovary Cancer
|
| Disease from KEGG |
Cell adhesion molecules
|
| Gene Ensembl |
ENSECAG00000008749, ENSMUSG00000051076, ENSCAFG00845029358, ENSBTAG00000062774, ENSMMUG00000016964, ENSG00000134258
|
| Target Classification |
Checkpoint-Immuno Oncology
|
Pre-made viral vector of B7‑H4/B7-H4/VTCN1 cDNA Clones/ORF Plasmid
B7‑H4/B7-H4/VTCN1 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo79679 | Pre-made Human VTCN1/B7X/B7H4 siRNA oligo Duplex | 79679 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo295322 | Pre-made Rat Vtcn1/RGD1311204 siRNA oligo Duplex | 295322 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo242122 | Pre-made Mouse Vtcn1/B7x/B7h4 siRNA oligo Duplex | 242122 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo714123 | Pre-made Cynomolgus/Rhesus macaque VTCN1 siRNA oligo Duplex | 714123 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101086586 | Pre-made Cat/Feline VTCN1 siRNA oligo Duplex | 101086586 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo483140 | Pre-made Dog/Canine VTCN1 siRNA oligo Duplex | 483140 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo539919 | Pre-made Bovines/Cattle VTCN1 siRNA oligo Duplex | 539919 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100066328 | Pre-made Equine/Horse VTCN1 siRNA oligo Duplex | 100066328 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
B7‑H4/B7-H4/VTCN1 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-IP0154-Ab | Human | Anti-Human B7‑H4/B7-H4/VTCN1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-rg-IP0154-Ab | Rat | Anti-Rat B7‑H4/B7-H4/VTCN1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-mg-IP0154-Ab | Mouse | Anti-Mouse B7‑H4/B7-H4/VTCN1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cynog-IP0154-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque B7‑H4/B7-H4/VTCN1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-felg-IP0154-Ab | Cat/Feline | Anti-Cat/Feline B7‑H4/B7-H4/VTCN1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cang-IP0154-Ab | Dog/Canine | Anti-Dog/Canine B7‑H4/B7-H4/VTCN1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-bovg-IP0154-Ab | Bovines/Cattle | Anti-Bovines/Cattle B7‑H4/B7-H4/VTCN1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-equg-IP0154-Ab | Equine/Horse | Anti-Equine/Horse B7‑H4/B7-H4/VTCN1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
B7‑H4/B7-H4/VTCN1 recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-IP0154-Ag | Human | Human B7‑H4/B7-H4/VTCN1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-IP0154-Ag | Rat | Rat B7‑H4/B7-H4/VTCN1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-IP0154-Ag | Mouse | Mouse B7‑H4/B7-H4/VTCN1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-IP0154-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque B7‑H4/B7-H4/VTCN1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-IP0154-Ag | Cat/Feline | Cat/Feline B7‑H4/B7-H4/VTCN1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-IP0154-Ag | Dog/Canine | Dog/Canine B7‑H4/B7-H4/VTCN1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-IP0154-Ag | Bovines/Cattle | Bovines/Cattle B7‑H4/B7-H4/VTCN1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-IP0154-Ag | Equine/Horse | Equine/Horse B7‑H4/B7-H4/VTCN1 recombinant protein | Mammalian cell | Detail |
