Explore MAP4K1 gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Introcelluar Protein.
Enables ATP binding activity and MAP kinase kinase kinase kinase activity. Involved in several processes, including JNK cascade; cellular response to phorbol 13-acetate 12-myristate; and protein phosphorylation. Located in membrane. [provided by Alliance of Genome Resources, Apr 2022]
| Target ID |
GM-IP0131
|
| Target Name |
MAP4K1
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
11184
|
| Gene ID |
100064279 (Equus caballus), 101101431 (Felis catus), 11184 (Homo sapiens), 26411 (Mus musculus)
292763 (Rattus norvegicus), 484527 (Canis lupus familiaris), 522002 (Bos taurus), 694259 (Macaca mulatta)
|
| Target Alternative Names |
HPK1,Hematopoietic progenitor kinase,Hpk1,MAP4K1,MAPK/ERK kinase kinase kinase 1 (MEK kinase kinase 1,MEKKK 1),Map4k1,Mitogen-activated protein kinase kinase kinase kinase 1,mHPK1
|
| Uniprot Accession |
Q92918,P70218
|
| Uniprot Entry Name |
|
| Protein Sub-location |
Introcelluar Protein
|
| Category |
Therapeutics Target
|
| Disease |
|
| Disease from KEGG |
MAPK signaling pathway
|
| Gene Ensembl |
ENSECAG00000017061, ENSG00000104814, ENSMUSG00000037337, ENSCAFG00845004960, ENSBTAG00000021145, ENSMMUG00000021630
|
| Target Classification |
Kinase
|
Pre-made viral vector of MAP4K1 cDNA Clones/ORF Plasmid
MAP4K1 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo11184 | Pre-made Human MAP4K1/HPK1 siRNA oligo Duplex | 11184 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo292763 | Pre-made Rat Map4k1/Hpk1 siRNA oligo Duplex | 292763 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo26411 | Pre-made Mouse Map4k1/Hpk1/mHPK1 siRNA oligo Duplex | 26411 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo694259 | Pre-made Cynomolgus/Rhesus macaque MAP4K1 siRNA oligo Duplex | 694259 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101101431 | Pre-made Cat/Feline MAP4K1 siRNA oligo Duplex | 101101431 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo484527 | Pre-made Dog/Canine MAP4K1 siRNA oligo Duplex | 484527 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo522002 | Pre-made Bovines/Cattle MAP4K1 siRNA oligo Duplex | 522002 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100064279 | Pre-made Equine/Horse MAP4K1 siRNA oligo Duplex | 100064279 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
MAP4K1 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-IP0131-Ab | Human | Anti-Human MAP4K1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-rg-IP0131-Ab | Rat | Anti-Rat MAP4K1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-mg-IP0131-Ab | Mouse | Anti-Mouse MAP4K1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cynog-IP0131-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque MAP4K1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-felg-IP0131-Ab | Cat/Feline | Anti-Cat/Feline MAP4K1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cang-IP0131-Ab | Dog/Canine | Anti-Dog/Canine MAP4K1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-bovg-IP0131-Ab | Bovines/Cattle | Anti-Bovines/Cattle MAP4K1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-equg-IP0131-Ab | Equine/Horse | Anti-Equine/Horse MAP4K1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
MAP4K1 recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-IP0131-Ag | Human | Human MAP4K1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-IP0131-Ag | Rat | Rat MAP4K1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-IP0131-Ag | Mouse | Mouse MAP4K1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-IP0131-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque MAP4K1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-IP0131-Ag | Cat/Feline | Cat/Feline MAP4K1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-IP0131-Ag | Dog/Canine | Dog/Canine MAP4K1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-IP0131-Ag | Bovines/Cattle | Bovines/Cattle MAP4K1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-IP0131-Ag | Equine/Horse | Equine/Horse MAP4K1 recombinant protein | Mammalian cell | Detail |
