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Target
sublocation: Introcelluar Protein.
This gene encodes a member of the alpha-2/delta subunit family, a protein in the voltage-dependent calcium channel complex. Calcium channels mediate the influx of calcium ions into the cell upon membrane polarization and consist of a complex of alpha-1, alpha-2/delta, beta, and gamma subunits in a 1:1:1:1 ratio. Various versions of each of these subunits exist, either expressed from similar genes or the result of alternative splicing. Research on a highly similar protein in rabbit suggests the protein described in this record is cleaved into alpha-2 and delta subunits. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized. [provided by RefSeq, Jul 2008]
| Target ID |
GM-IP0129
|
| Target Name |
CACNA2D3
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
55799
|
| Gene ID |
100059197 (Equus caballus), 101094658 (Felis catus), 12294 (Mus musculus), 306243 (Rattus norvegicus)
476585 (Canis lupus familiaris), 519644 (Bos taurus), 55799 (Homo sapiens), 693356 (Macaca mulatta)
|
| Target Alternative Names |
CACNA2D3,Cacna2d3,Cacnad3,HSA272268,Voltage-dependent calcium channel subunit alpha-2/delta-3,Voltage-gated calcium channel subunit alpha-2/delta-3,alapha2delta3
|
| Uniprot Accession |
Q9Z1L5,Q8CFG5,Q8IZS8
|
| Protein Sub-location |
Introcelluar Protein
|
| Category |
Therapeutics Target
|
| Disease from KEGG |
MAPK signaling pathway, Adrenergic signaling in cardiomyocytes, Oxytocin signaling pathway, Hypertrophic cardiomyopathy, Arrhythmogenic right ventricular cardiomyopathy, Dilated cardiomyopathy
|
| Gene Ensembl |
ENSECAG00000014305, ENSMUSG00000021991, ENSCAFG00845026635, ENSBTAG00000013117, ENSG00000157445, ENSMMUG00000047365
|
Pre-made viral vector of CACNA2D3 cDNA Clones/ORF Plasmid
CACNA2D3 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo55799 | Pre-made Human CACNA2D3/HSA272268 siRNA oligo Duplex | 55799 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo306243 | Pre-made Rat Cacna2d3 siRNA oligo Duplex | 306243 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo12294 | Pre-made Mouse Cacna2d3/Cacnad3/alapha2delta3 siRNA oligo Duplex | 12294 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo693356 | Pre-made Cynomolgus/Rhesus macaque CACNA2D3 siRNA oligo Duplex | 693356 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101094658 | Pre-made Cat/Feline CACNA2D3 siRNA oligo Duplex | 101094658 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo476585 | Pre-made Dog/Canine CACNA2D3 siRNA oligo Duplex | 476585 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo519644 | Pre-made Bovines/Cattle CACNA2D3 siRNA oligo Duplex | 519644 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100059197 | Pre-made Equine/Horse CACNA2D3 siRNA oligo Duplex | 100059197 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
CACNA2D3 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-IP0129-Ab | Human | Anti-Human CACNA2D3 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-rg-IP0129-Ab | Rat | Anti-Rat CACNA2D3 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-mg-IP0129-Ab | Mouse | Anti-Mouse CACNA2D3 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cynog-IP0129-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque CACNA2D3 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-felg-IP0129-Ab | Cat/Feline | Anti-Cat/Feline CACNA2D3 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cang-IP0129-Ab | Dog/Canine | Anti-Dog/Canine CACNA2D3 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-bovg-IP0129-Ab | Bovines/Cattle | Anti-Bovines/Cattle CACNA2D3 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-equg-IP0129-Ab | Equine/Horse | Anti-Equine/Horse CACNA2D3 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
CACNA2D3 recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-IP0129-Ag | Human | Human CACNA2D3 recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-IP0129-Ag | Rat | Rat CACNA2D3 recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-IP0129-Ag | Mouse | Mouse CACNA2D3 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-IP0129-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque CACNA2D3 recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-IP0129-Ag | Cat/Feline | Cat/Feline CACNA2D3 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-IP0129-Ag | Dog/Canine | Dog/Canine CACNA2D3 recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-IP0129-Ag | Bovines/Cattle | Bovines/Cattle CACNA2D3 recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-IP0129-Ag | Equine/Horse | Equine/Horse CACNA2D3 recombinant protein | Mammalian cell | Detail |
