Explore GSR/GR gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
premier destination for multi-species gene research solutions
Target
sublocation: Introcelluar Protein.
This gene encodes a member of the class-I pyridine nucleotide-disulfide oxidoreductase family. This enzyme is a homodimeric flavoprotein. It is a central enzyme of cellular antioxidant defense, and reduces oxidized glutathione disulfide (GSSG) to the sulfhydryl form GSH, which is an important cellular antioxidant. Rare mutations in this gene result in hereditary glutathione reductase deficiency. Multiple alternatively spliced transcript variants encoding different isoforms have been found. [provided by RefSeq, Aug 2010]
| Target ID |
GM-IP0087
|
| Target Name |
GSR/GR
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
2936
|
| Gene ID |
100062365 (Equus caballus), 100425521 (Macaca mulatta), 101094413 (Felis catus), 116686 (Rattus norvegicus)
14782 (Mus musculus), 2936 (Homo sapiens), 475596 (Canis lupus familiaris), 506406 (Bos taurus)
|
| Target Alternative Names |
CNSHA10,D8Ertd238e,GR,GRase,GSR,GSRD,Glutathione reductase,Gr-1,Gr1,Gsr,HEL-75,HEL-S-122m,mitochondrial
|
| Uniprot Accession |
P70619,P47791,P00390
|
| Protein Sub-location |
Introcelluar Protein
|
| Category |
Therapeutics Target
|
| Disease from KEGG |
Metabolic pathways, Thyroid hormone synthesis
|
| Gene Ensembl |
ENSECAG00000014178, ENSMMUG00000039030, ENSMUSG00000031584, ENSG00000104687, ENSCAFG00845016475, ENSBTAG00000007115
|
Pre-made viral vector of GSR/GR cDNA Clones/ORF Plasmid
GSR/GR siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo2936 | Pre-made Human GSR/GR/GSRD siRNA oligo Duplex | 2936 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo116686 | Pre-made Rat Gsr siRNA oligo Duplex | 116686 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo14782 | Pre-made Mouse Gsr/Gr1/Gr-1 siRNA oligo Duplex | 14782 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100425521 | Pre-made Cynomolgus/Rhesus macaque GSR siRNA oligo Duplex | 100425521 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101094413 | Pre-made Cat/Feline GSR siRNA oligo Duplex | 101094413 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo475596 | Pre-made Dog/Canine GSR siRNA oligo Duplex | 475596 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo506406 | Pre-made Bovines/Cattle GSR siRNA oligo Duplex | 506406 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100062365 | Pre-made Equine/Horse GSR siRNA oligo Duplex | 100062365 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
GSR/GR antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-IP0087-Ab | Human | Anti-Human GSR/GR monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-rg-IP0087-Ab | Rat | Anti-Rat GSR/GR monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-mg-IP0087-Ab | Mouse | Anti-Mouse GSR/GR monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cynog-IP0087-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque GSR/GR monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-felg-IP0087-Ab | Cat/Feline | Anti-Cat/Feline GSR/GR monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cang-IP0087-Ab | Dog/Canine | Anti-Dog/Canine GSR/GR monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-bovg-IP0087-Ab | Bovines/Cattle | Anti-Bovines/Cattle GSR/GR monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-equg-IP0087-Ab | Equine/Horse | Anti-Equine/Horse GSR/GR monoclonal antibody | mab | Therapeutics Target antibody | Detail |
GSR/GR recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-IP0087-Ag | Human | Human GSR/GR recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-IP0087-Ag | Rat | Rat GSR/GR recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-IP0087-Ag | Mouse | Mouse GSR/GR recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-IP0087-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque GSR/GR recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-IP0087-Ag | Cat/Feline | Cat/Feline GSR/GR recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-IP0087-Ag | Dog/Canine | Dog/Canine GSR/GR recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-IP0087-Ag | Bovines/Cattle | Bovines/Cattle GSR/GR recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-IP0087-Ag | Equine/Horse | Equine/Horse GSR/GR recombinant protein | Mammalian cell | Detail |
