Explore DLL3 gene products and cross-species
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biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Introcelluar Protein.
This gene encodes a member of the delta protein ligand family. This family functions as Notch ligands that are characterized by a DSL domain, EGF repeats, and a transmembrane domain. Mutations in this gene cause autosomal recessive spondylocostal dysostosis 1. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008]
| Target ID |
GM-IP0082
|
| Target Name |
DLL3
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
10683
|
| Gene ID |
100067648 (Equus caballus), 101095456 (Felis catus), 10683 (Homo sapiens), 114125 (Rattus norvegicus)
13389 (Mus musculus), 484508 (Canis lupus familiaris), 505993 (Bos taurus), 697453 (Macaca mulatta)
|
| Target Alternative Names |
DLL3,Delta-like protein 3,Dll3,Drosophila Delta homolog 3 (Delta3),SCDO1,pu,pudgy
|
| Uniprot Accession |
Q9NYJ7,O88671,O88516
|
| Protein Sub-location |
Introcelluar Protein
|
| Category |
Therapeutics Target, Immuno-oncology Target, INN Index
|
| Disease from KEGG |
Endocrine resistance, Th1 and Th2 cell differentiation, Pathways in cancer, Chemical carcinogenesis - receptor activation, Breast cancer
|
| Gene Ensembl |
ENSECAG00000007731, ENSG00000090932, ENSMUSG00000003436, ENSCAFG00845004619, ENSBTAG00000010483, ENSMMUG00000019093
|
| Target Classification |
Checkpoint-Immuno Oncology
|
Pre-made viral vector of DLL3 cDNA Clones/ORF Plasmid
DLL3 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo10683 | Pre-made Human DLL3/SCDO1 siRNA oligo Duplex | 10683 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo114125 | Pre-made Rat Dll3 siRNA oligo Duplex | 114125 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo13389 | Pre-made Mouse Dll3/pu/pudgy siRNA oligo Duplex | 13389 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo697453 | Pre-made Cynomolgus/Rhesus macaque DLL3 siRNA oligo Duplex | 697453 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101095456 | Pre-made Cat/Feline DLL3 siRNA oligo Duplex | 101095456 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo484508 | Pre-made Dog/Canine DLL3 siRNA oligo Duplex | 484508 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo505993 | Pre-made Bovines/Cattle DLL3 siRNA oligo Duplex | 505993 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100067648 | Pre-made Equine/Horse DLL3 siRNA oligo Duplex | 100067648 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
DLL3 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-IP0082-Ab | Human | Anti-Human DLL3 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-rg-IP0082-Ab | Rat | Anti-Rat DLL3 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-mg-IP0082-Ab | Mouse | Anti-Mouse DLL3 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cynog-IP0082-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque DLL3 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-felg-IP0082-Ab | Cat/Feline | Anti-Cat/Feline DLL3 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cang-IP0082-Ab | Dog/Canine | Anti-Dog/Canine DLL3 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-bovg-IP0082-Ab | Bovines/Cattle | Anti-Bovines/Cattle DLL3 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-equg-IP0082-Ab | Equine/Horse | Anti-Equine/Horse DLL3 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
DLL3 recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-IP0082-Ag | Human | Human DLL3 recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-IP0082-Ag | Rat | Rat DLL3 recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-IP0082-Ag | Mouse | Mouse DLL3 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-IP0082-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque DLL3 recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-IP0082-Ag | Cat/Feline | Cat/Feline DLL3 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-IP0082-Ag | Dog/Canine | Dog/Canine DLL3 recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-IP0082-Ag | Bovines/Cattle | Bovines/Cattle DLL3 recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-IP0082-Ag | Equine/Horse | Equine/Horse DLL3 recombinant protein | Mammalian cell | Detail |
