Explore Fascin/FSCN1 gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
premier destination for multi-species gene research solutions
Target
sublocation: Introcelluar Protein.
This gene encodes a member of the fascin family of actin-binding proteins. Fascin proteins organize F-actin into parallel bundles, and are required for the formation of actin-based cellular protrusions. The encoded protein plays a critical role in cell migration, motility, adhesion and cellular interactions. Expression of this gene is known to be regulated by several microRNAs, and overexpression of this gene may play a role in the metastasis of multiple types of cancer by increasing cell motility. Expression of this gene is also a marker for Reed-Sternberg cells in Hodgkin's lymphoma. A pseudogene of this gene is located on the long arm of chromosome 15. [provided by RefSeq, Sep 2011]
| Target ID |
GM-IP0081
|
| Target Name |
Fascin/FSCN1
|
Gene Group ldentifer (Target Gene ID in Homo
species)
|
6624
|
| Gene ID |
100146921 (Equus caballus), 100430727 (Macaca mulatta), 101098761 (Felis catus), 14086 (Mus musculus) 489880 (Canis lupus familiaris), 507342 (Bos taurus), 6624 (Homo sapiens), 683788 (Rattus norvegicus)
|
| Target Alternative Names |
55 kDa actin-bundling protein,FAN1,FSCN1,Fan1,Fascin,Fscn1,HSN,SNL,Singed-like protein,fascin,fascin-1,p55
|
| Uniprot Accession |
Q61553,Q16658,P85845
|
| Protein Sub-location |
Introcelluar Protein
|
| Category |
Therapeutics Target
|
| Disease |
cancer, lung cancer
|
| Gene Ensembl |
ENSECAG00000008056, ENSMMUG00000004282, ENSMUSG00000029581, ENSCAFG00845013389, ENSBTAG00000003191, ENSG00000075618
|
Pre-made viral vector of Fascin/FSCN1 cDNA Clones/ORF Plasmid
Fascin/FSCN1 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo6624 | Pre-made Human FSCN1/HSN/SNL siRNA oligo Duplex | 6624 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo683788 | Pre-made Rat Fscn1/Fascin siRNA oligo Duplex | 683788 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo14086 | Pre-made Mouse Fscn1/Fan1/fascin-1 siRNA oligo Duplex | 14086 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100430727 | Pre-made Cynomolgus/Rhesus macaque FSCN1/fascin siRNA oligo Duplex | 100430727 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101098761 | Pre-made Cat/Feline FSCN1 siRNA oligo Duplex | 101098761 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo489880 | Pre-made Dog/Canine FSCN1 siRNA oligo Duplex | 489880 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo507342 | Pre-made Bovines/Cattle FSCN1 siRNA oligo Duplex | 507342 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100146921 | Pre-made Equine/Horse FSCN1 siRNA oligo Duplex | 100146921 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
Fascin/FSCN1 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-IP0081-Ab | Human | Anti-Human Fascin/FSCN1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-rg-IP0081-Ab | Rat | Anti-Rat Fascin/FSCN1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-mg-IP0081-Ab | Mouse | Anti-Mouse Fascin/FSCN1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cynog-IP0081-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque Fascin/FSCN1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-felg-IP0081-Ab | Cat/Feline | Anti-Cat/Feline Fascin/FSCN1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cang-IP0081-Ab | Dog/Canine | Anti-Dog/Canine Fascin/FSCN1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-bovg-IP0081-Ab | Bovines/Cattle | Anti-Bovines/Cattle Fascin/FSCN1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-equg-IP0081-Ab | Equine/Horse | Anti-Equine/Horse Fascin/FSCN1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
Fascin/FSCN1 recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-IP0081-Ag | Human | Human Fascin/FSCN1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-IP0081-Ag | Rat | Rat Fascin/FSCN1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-IP0081-Ag | Mouse | Mouse Fascin/FSCN1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-IP0081-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque Fascin/FSCN1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-IP0081-Ag | Cat/Feline | Cat/Feline Fascin/FSCN1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-IP0081-Ag | Dog/Canine | Dog/Canine Fascin/FSCN1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-IP0081-Ag | Bovines/Cattle | Bovines/Cattle Fascin/FSCN1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-IP0081-Ag | Equine/Horse | Equine/Horse Fascin/FSCN1 recombinant protein | Mammalian cell | Detail |