Explore MNK1/MKNK1 gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Introcelluar Protein.
This gene encodes a Ser/Thr protein kinase that interacts with, and is activated by ERK1 and p38 mitogen-activated protein kinases, and thus may play a role in the response to environmental stress and cytokines. This kinase may also regulate transcription by phosphorylating eIF4E via interaction with the C-terminal region of eIF4G. Alternatively spliced transcript variants have been noted for this gene. [provided by RefSeq, Jan 2012]
| Target ID |
GM-IP0063
|
| Target Name |
MNK1/MKNK1
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
8569
|
| Gene ID |
100064521 (Equus caballus), 101082505 (Felis catus), 17346 (Mus musculus), 482509 (Canis lupus familiaris)
500526 (Rattus norvegicus), 525647 (Bos taurus), 710061 (Macaca mulatta), 8569 (Homo sapiens)
|
| Target Alternative Names |
MKNK1,Mknk1,Mnk1,2410048M24Rik,MNK1
|
| Uniprot Accession |
O08605,Q4G050,Q58D94,Q9BUB5
|
| Uniprot Entry Name |
|
| Protein Sub-location |
Introcelluar Protein
|
| Category |
Therapeutics Target
|
| Disease |
|
| Disease from KEGG |
MAPK signaling pathway, HIF-1 signaling pathway
|
| Gene Ensembl |
ENSECAG00000000735, ENSMUSG00000028708, ENSCAFG00845018913, ENSBTAG00000019933, ENSMMUG00000020162, ENSG00000079277
|
| Target Classification |
|
Pre-made viral vector of MNK1/MKNK1 cDNA Clones/ORF Plasmid
MNK1/MKNK1 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo8569 | Pre-made Human MKNK1/MNK1 siRNA oligo Duplex | 8569 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo500526 | Pre-made Rat Mknk1 siRNA oligo Duplex | 500526 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo17346 | Pre-made Mouse Mknk1/Mnk1/2410048M24Rik siRNA oligo Duplex | 17346 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo710061 | Pre-made Cynomolgus/Rhesus macaque MKNK1 siRNA oligo Duplex | 710061 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101082505 | Pre-made Cat/Feline MKNK1 siRNA oligo Duplex | 101082505 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo482509 | Pre-made Dog/Canine MKNK1 siRNA oligo Duplex | 482509 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo525647 | Pre-made Bovines/Cattle MKNK1 siRNA oligo Duplex | 525647 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100064521 | Pre-made Equine/Horse MKNK1 siRNA oligo Duplex | 100064521 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
MNK1/MKNK1 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-IP0063-Ab | Human | Anti-Human MNK1/MKNK1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-rg-IP0063-Ab | Rat | Anti-Rat MNK1/MKNK1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-mg-IP0063-Ab | Mouse | Anti-Mouse MNK1/MKNK1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cynog-IP0063-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque MNK1/MKNK1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-felg-IP0063-Ab | Cat/Feline | Anti-Cat/Feline MNK1/MKNK1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cang-IP0063-Ab | Dog/Canine | Anti-Dog/Canine MNK1/MKNK1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-bovg-IP0063-Ab | Bovines/Cattle | Anti-Bovines/Cattle MNK1/MKNK1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-equg-IP0063-Ab | Equine/Horse | Anti-Equine/Horse MNK1/MKNK1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
MNK1/MKNK1 recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-IP0063-Ag | Human | Human MNK1/MKNK1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-IP0063-Ag | Rat | Rat MNK1/MKNK1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-IP0063-Ag | Mouse | Mouse MNK1/MKNK1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-IP0063-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque MNK1/MKNK1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-IP0063-Ag | Cat/Feline | Cat/Feline MNK1/MKNK1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-IP0063-Ag | Dog/Canine | Dog/Canine MNK1/MKNK1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-IP0063-Ag | Bovines/Cattle | Bovines/Cattle MNK1/MKNK1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-IP0063-Ag | Equine/Horse | Equine/Horse MNK1/MKNK1 recombinant protein | Mammalian cell | Detail |
