Explore CYP24A1 gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
premier destination for multi-species gene research solutions
Target
sublocation: Introcelluar Protein.
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This mitochondrial protein initiates the degradation of 1,25-dihydroxyvitamin D3, the physiologically active form of vitamin D3, by hydroxylation of the side chain. In regulating the level of vitamin D3, this enzyme plays a role in calcium homeostasis and the vitamin D endocrine system. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
| Target ID |
GM-IP0059
|
| Target Name |
CYP24A1
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
1591
|
| Gene ID |
100053452 (Equus caballus), 101096141 (Felis catus), 13081 (Mus musculus), 1591 (Homo sapiens)
25279 (Rattus norvegicus), 485935 (Canis lupus familiaris), 540080 (Bos taurus), 698937 (Macaca mulatta)
|
| Target Alternative Names |
1,24-OHase,24R-Ohase,25-dihydroxyvitamin D(3) 24-hydroxylase,CP24,CYP24,CYP24A1,Cyp24,Cyp24a1,Cytochrome P450 24A1,Cytochrome P450-CC24,HCAI,HCINF1,P450-CC24,VITD12,Vitamin D(3) 24-hydroxylase,mitochondrial
|
| Uniprot Accession |
Q64441,Q07973,Q09128
|
| Protein Sub-location |
Introcelluar Protein
|
| Category |
Therapeutics Target
|
| Disease |
cancer, Lung Cancer
|
| Disease from KEGG |
Steroid biosynthesis, Metabolic pathways, Parathyroid hormone synthesis, secretion and action
|
| Gene Ensembl |
ENSECAG00000016322, ENSMUSG00000038567, ENSG00000019186, ENSCAFG00845028958, ENSBTAG00000002765, ENSMMUG00000014860
|
CYP24A1 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo1591 | Pre-made Human CYP24A1/CP24/HCAI siRNA oligo Duplex | 1591 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo25279 | Pre-made Rat Cyp24a1/Cyp24/VITD12 siRNA oligo Duplex | 25279 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo13081 | Pre-made Mouse Cyp24a1/CP24/Cyp24 siRNA oligo Duplex | 13081 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo698937 | Pre-made Cynomolgus/Rhesus macaque CYP24A1 siRNA oligo Duplex | 698937 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101096141 | Pre-made Cat/Feline CYP24A1 siRNA oligo Duplex | 101096141 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo485935 | Pre-made Dog/Canine CYP24A1 siRNA oligo Duplex | 485935 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo540080 | Pre-made Bovines/Cattle CYP24A1 siRNA oligo Duplex | 540080 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100053452 | Pre-made Equine/Horse CYP24A1 siRNA oligo Duplex | 100053452 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
CYP24A1 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-IP0059-Ab | Human | Anti-Human CYP24A1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-rg-IP0059-Ab | Rat | Anti-Rat CYP24A1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-mg-IP0059-Ab | Mouse | Anti-Mouse CYP24A1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cynog-IP0059-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque CYP24A1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-felg-IP0059-Ab | Cat/Feline | Anti-Cat/Feline CYP24A1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cang-IP0059-Ab | Dog/Canine | Anti-Dog/Canine CYP24A1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-bovg-IP0059-Ab | Bovines/Cattle | Anti-Bovines/Cattle CYP24A1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-equg-IP0059-Ab | Equine/Horse | Anti-Equine/Horse CYP24A1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
CYP24A1 recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-IP0059-Ag | Human | Human CYP24A1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-IP0059-Ag | Rat | Rat CYP24A1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-IP0059-Ag | Mouse | Mouse CYP24A1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-IP0059-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque CYP24A1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-IP0059-Ag | Cat/Feline | Cat/Feline CYP24A1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-IP0059-Ag | Dog/Canine | Dog/Canine CYP24A1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-IP0059-Ag | Bovines/Cattle | Bovines/Cattle CYP24A1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-IP0059-Ag | Equine/Horse | Equine/Horse CYP24A1 recombinant protein | Mammalian cell | Detail |
