Explore TSPO/PBR gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Introcelluar Protein.
Present mainly in the mitochondrial compartment of peripheral tissues, the protein encoded by this gene interacts with some benzodiazepines and has different affinities than its endogenous counterpart. The protein is a key factor in the flow of cholesterol into mitochondria to permit the initiation of steroid hormone synthesis. Alternatively spliced transcript variants have been reported; one of the variants lacks an internal exon and is considered non-coding, and the other variants encode the same protein. [provided by RefSeq, Feb 2012]
| Target ID |
GM-IP0017
|
| Target Name |
TSPO/PBR
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
706
|
| Gene ID |
100071110 (Equus caballus), 101087076 (Felis catus), 12257 (Mus musculus), 24230 (Rattus norvegicus)
281033 (Bos taurus), 474475 (Canis lupus familiaris), 706 (Homo sapiens), 711717 (Macaca mulatta)
|
| Target Alternative Names |
BPBS,BZRP,Bzrp,DBI,IBP,MBR,Mitochondrial benzodiazepine receptor,PBR,PBS,PKBS,PTBR,PTBZR02,Peripheral-type benzodiazepine receptor (PBR),Ptbzr,RATPTBZR02,TSPO,TSPO1,Translocator protein,Tspo,Tspo1,mDRC,pk18
|
| Uniprot Accession |
P50637,P16257,P30535,P30536
|
| Protein Sub-location |
Introcelluar Protein
|
| Category |
Therapeutics Target
|
| Disease |
cancer, Breast Cancer
|
| Disease from KEGG |
Neuroactive ligand-receptor interaction, Cholesterol metabolism, Human T-cell leukemia virus 1 infection
|
| Gene Ensembl |
ENSECAG00000021765, ENSMUSG00000041736, ENSBTAG00000018073, ENSCAFG00845014235, ENSG00000100300, ENSMMUG00000006058
|
Pre-made viral vector of TSPO/PBR cDNA Clones/ORF Plasmid
TSPO/PBR siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo706 | Pre-made Human TSPO/DBI/IBP siRNA oligo Duplex | 706 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo24230 | Pre-made Rat Tspo/MBR/Bzrp siRNA oligo Duplex | 24230 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo12257 | Pre-made Mouse Tspo/IBP/PBR siRNA oligo Duplex | 12257 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo711717 | Pre-made Cynomolgus/Rhesus macaque TSPO/BZRP siRNA oligo Duplex | 711717 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101087076 | Pre-made Cat/Feline TSPO siRNA oligo Duplex | 101087076 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo474475 | Pre-made Dog/Canine TSPO siRNA oligo Duplex | 474475 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo281033 | Pre-made Bovines/Cattle TSPO/BZRP siRNA oligo Duplex | 281033 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100071110 | Pre-made Equine/Horse TSPO siRNA oligo Duplex | 100071110 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
TSPO/PBR antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-IP0017-Ab | Human | Anti-Human TSPO/PBR monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-rg-IP0017-Ab | Rat | Anti-Rat TSPO/PBR monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-mg-IP0017-Ab | Mouse | Anti-Mouse TSPO/PBR monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cynog-IP0017-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque TSPO/PBR monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-felg-IP0017-Ab | Cat/Feline | Anti-Cat/Feline TSPO/PBR monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cang-IP0017-Ab | Dog/Canine | Anti-Dog/Canine TSPO/PBR monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-bovg-IP0017-Ab | Bovines/Cattle | Anti-Bovines/Cattle TSPO/PBR monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-equg-IP0017-Ab | Equine/Horse | Anti-Equine/Horse TSPO/PBR monoclonal antibody | mab | Therapeutics Target antibody | Detail |
TSPO/PBR recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-IP0017-Ag | Human | Human TSPO/PBR recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-IP0017-Ag | Rat | Rat TSPO/PBR recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-IP0017-Ag | Mouse | Mouse TSPO/PBR recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-IP0017-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque TSPO/PBR recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-IP0017-Ag | Cat/Feline | Cat/Feline TSPO/PBR recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-IP0017-Ag | Dog/Canine | Dog/Canine TSPO/PBR recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-IP0017-Ag | Bovines/Cattle | Bovines/Cattle TSPO/PBR recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-IP0017-Ag | Equine/Horse | Equine/Horse TSPO/PBR recombinant protein | Mammalian cell | Detail |
