Explore RRM2 gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Introcelluar Protein.
This gene encodes one of two non-identical subunits for ribonucleotide reductase. This reductase catalyzes the formation of deoxyribonucleotides from ribonucleotides. Synthesis of the encoded protein (M2) is regulated in a cell-cycle dependent fashion. Transcription from this gene can initiate from alternative promoters, which results in two isoforms that differ in the lengths of their N-termini. Related pseudogenes have been identified on chromosomes 1 and X. [provided by RefSeq, Sep 2009]
| Target ID |
GM-IP0011
|
| Target Name |
RRM2
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
6241
|
| Gene ID |
100072410 (Equus caballus), 101087987 (Felis catus), 20135 (Mus musculus), 362720 (Rattus norvegicus)
482963 (Canis lupus familiaris), 508167 (Bos taurus), 6241 (Homo sapiens), 703138 (Macaca mulatta)
|
| Target Alternative Names |
C2orf48,R2,RR2,RR2M,RRM2,Rrm2
|
| Uniprot Accession |
P11157,Q4KLN6,P31350,Q96LS8
|
| Protein Sub-location |
Introcelluar Protein
|
| Category |
Therapeutics Target
|
| Disease |
cancer
|
| Disease from KEGG |
Metabolic pathways, p53 signaling pathway
|
| Gene Ensembl |
ENSECAG00000007464, ENSMUSG00000020649, ENSCAFG00845025952, ENSBTAG00000008216, ENSG00000171848, ENSMMUG00000002057
|
Pre-made viral vector of RRM2 cDNA Clones/ORF Plasmid
RRM2 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo6241 | Pre-made Human RRM2/R2/RR2 siRNA oligo Duplex | 6241 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo362720 | Pre-made Rat Rrm2 siRNA oligo Duplex | 362720 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo20135 | Pre-made Mouse Rrm2/R2 siRNA oligo Duplex | 20135 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo703138 | Pre-made Cynomolgus/Rhesus macaque RRM2 siRNA oligo Duplex | 703138 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101087987 | Pre-made Cat/Feline RRM2 siRNA oligo Duplex | 101087987 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo482963 | Pre-made Dog/Canine RRM2 siRNA oligo Duplex | 482963 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo508167 | Pre-made Bovines/Cattle RRM2 siRNA oligo Duplex | 508167 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100072410 | Pre-made Equine/Horse RRM2 siRNA oligo Duplex | 100072410 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
RRM2 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-IP0011-Ab | Human | Anti-Human RRM2 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-rg-IP0011-Ab | Rat | Anti-Rat RRM2 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-mg-IP0011-Ab | Mouse | Anti-Mouse RRM2 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cynog-IP0011-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque RRM2 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-felg-IP0011-Ab | Cat/Feline | Anti-Cat/Feline RRM2 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cang-IP0011-Ab | Dog/Canine | Anti-Dog/Canine RRM2 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-bovg-IP0011-Ab | Bovines/Cattle | Anti-Bovines/Cattle RRM2 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-equg-IP0011-Ab | Equine/Horse | Anti-Equine/Horse RRM2 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
RRM2 recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-IP0011-Ag | Human | Human RRM2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-IP0011-Ag | Rat | Rat RRM2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-IP0011-Ag | Mouse | Mouse RRM2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-IP0011-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque RRM2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-IP0011-Ag | Cat/Feline | Cat/Feline RRM2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-IP0011-Ag | Dog/Canine | Dog/Canine RRM2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-IP0011-Ag | Bovines/Cattle | Bovines/Cattle RRM2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-IP0011-Ag | Equine/Horse | Equine/Horse RRM2 recombinant protein | Mammalian cell | Detail |
