Explore B-Myb/MYBL2 gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Introcelluar Protein.
The protein encoded by this gene, a member of the MYB family of transcription factor genes, is a nuclear protein involved in cell cycle progression. The encoded protein is phosphorylated by cyclin A/cyclin-dependent kinase 2 during the S-phase of the cell cycle and possesses both activator and repressor activities. It has been shown to activate the cell division cycle 2, cyclin D1, and insulin-like growth factor-binding protein 5 genes. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2013]
| Target ID |
GM-IO108
|
| Target Name |
B-Myb/MYBL2
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
4605
|
| Gene ID |
100070694 (Equus caballus), 101095245 (Felis catus), 17865 (Mus musculus), 296344 (Rattus norvegicus)
4605 (Homo sapiens), 477232 (Canis lupus familiaris), 510420 (Bos taurus), 694693 (Macaca mulatta)
|
| Target Alternative Names |
B-MYB,B-Myb,BMYB,Bmyb,MYBL2,Myb-like protein 2,Myb-related protein B,Mybl2
|
| Uniprot Accession |
P48972,P10244
|
| Protein Sub-location |
Introcelluar Protein
|
| Category |
Therapeutics Target, Immuno-oncology Target
|
| Disease |
cancer, Breast Cancer
|
| Disease from KEGG |
Cellular senescence
|
| Gene Ensembl |
ENSECAG00000005925, ENSMUSG00000017861, ENSG00000101057, ENSCAFG00845013268, ENSBTAG00000007783, ENSMMUG00000018137
|
| Target Classification |
Checkpoint-Immuno Oncology
|
Pre-made viral vector of B-Myb/MYBL2 cDNA Clones/ORF Plasmid
B-Myb/MYBL2 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo4605 | Pre-made Human MYBL2/BMYB/B-MYB siRNA oligo Duplex | 4605 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo296344 | Pre-made Rat Mybl2 siRNA oligo Duplex | 296344 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo17865 | Pre-made Mouse Mybl2/Bmyb/B-Myb siRNA oligo Duplex | 17865 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo694693 | Pre-made Cynomolgus/Rhesus macaque MYBL2 siRNA oligo Duplex | 694693 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101095245 | Pre-made Cat/Feline MYBL2 siRNA oligo Duplex | 101095245 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo477232 | Pre-made Dog/Canine MYBL2 siRNA oligo Duplex | 477232 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo510420 | Pre-made Bovines/Cattle MYBL2/BMYB siRNA oligo Duplex | 510420 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100070694 | Pre-made Equine/Horse MYBL2 siRNA oligo Duplex | 100070694 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
B-Myb/MYBL2 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-IO108-Ab | Human | Anti-Human B-Myb/MYBL2 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-rg-IO108-Ab | Rat | Anti-Rat B-Myb/MYBL2 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-mg-IO108-Ab | Mouse | Anti-Mouse B-Myb/MYBL2 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cynog-IO108-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque B-Myb/MYBL2 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-felg-IO108-Ab | Cat/Feline | Anti-Cat/Feline B-Myb/MYBL2 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cang-IO108-Ab | Dog/Canine | Anti-Dog/Canine B-Myb/MYBL2 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-bovg-IO108-Ab | Bovines/Cattle | Anti-Bovines/Cattle B-Myb/MYBL2 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-equg-IO108-Ab | Equine/Horse | Anti-Equine/Horse B-Myb/MYBL2 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
B-Myb/MYBL2 recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-IO108-Ag | Human | Human B-Myb/MYBL2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-IO108-Ag | Rat | Rat B-Myb/MYBL2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-IO108-Ag | Mouse | Mouse B-Myb/MYBL2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-IO108-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque B-Myb/MYBL2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-IO108-Ag | Cat/Feline | Cat/Feline B-Myb/MYBL2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-IO108-Ag | Dog/Canine | Dog/Canine B-Myb/MYBL2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-IO108-Ag | Bovines/Cattle | Bovines/Cattle B-Myb/MYBL2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-IO108-Ag | Equine/Horse | Equine/Horse B-Myb/MYBL2 recombinant protein | Mammalian cell | Detail |
