Explore MVP gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Introcelluar Protein.
This gene encodes the major component of the vault complex. Vaults are multi-subunit ribonucleoprotein structures that may be involved in nucleo-cytoplasmic transport. The encoded protein may play a role in multiple cellular processes by regulating the MAP kinase, JAK/STAT and phosphoinositide 3-kinase/Akt signaling pathways. The encoded protein also plays a role in multidrug resistance, and expression of this gene may be a prognostic marker for several types of cancer. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, May 2012]
| Target ID |
GM-IO106
|
| Target Name |
MVP
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
9961
|
| Gene ID |
100063984 (Equus caballus), 479783 (Canis lupus familiaris), 516456 (Bos taurus), 64681 (Rattus norvegicus)
706736 (Macaca mulatta), 727688 (Felis catus), 78388 (Mus musculus), 9961 (Homo sapiens)
|
| Target Alternative Names |
2310009M24Rik,LRP,Lung resistance-related protein,MVP,Major vault protein,Mvp,VAULT1
|
| Uniprot Accession |
Q3SYU9,Q62667,Q9EQK5,Q14764
|
| Protein Sub-location |
Introcelluar Protein
|
| Category |
Therapeutics Target, Immuno-oncology Target
|
| Disease |
cancer
|
| Gene Ensembl |
ENSECAG00000025091, ENSCAFG00845000844, ENSBTAG00000007952, ENSMMUG00000016422, ENSMUSG00000030681, ENSG00000013364
|
| Target Classification |
Checkpoint-Immuno Oncology, Tumor-associated antigen (TAA)
|
Pre-made viral vector of MVP cDNA Clones/ORF Plasmid
MVP siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo9961 | Pre-made Human MVP/LRP/VAULT1 siRNA oligo Duplex | 9961 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo64681 | Pre-made Rat Mvp siRNA oligo Duplex | 64681 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo78388 | Pre-made Mouse Mvp/LRP/VAULT1 siRNA oligo Duplex | 78388 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo706736 | Pre-made Cynomolgus/Rhesus macaque MVP siRNA oligo Duplex | 706736 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo727688 | Pre-made Cat/Feline MVP/LRP siRNA oligo Duplex | 727688 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo479783 | Pre-made Dog/Canine MVP/LRP siRNA oligo Duplex | 479783 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo516456 | Pre-made Bovines/Cattle MVP siRNA oligo Duplex | 516456 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100063984 | Pre-made Equine/Horse MVP siRNA oligo Duplex | 100063984 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
MVP antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-IO106-Ab | Human | Anti-Human MVP monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-rg-IO106-Ab | Rat | Anti-Rat MVP monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-mg-IO106-Ab | Mouse | Anti-Mouse MVP monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cynog-IO106-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque MVP monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-felg-IO106-Ab | Cat/Feline | Anti-Cat/Feline MVP monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cang-IO106-Ab | Dog/Canine | Anti-Dog/Canine MVP monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-bovg-IO106-Ab | Bovines/Cattle | Anti-Bovines/Cattle MVP monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-equg-IO106-Ab | Equine/Horse | Anti-Equine/Horse MVP monoclonal antibody | mab | Therapeutics Target antibody | Detail |
MVP recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-IO106-Ag | Human | Human MVP recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-IO106-Ag | Rat | Rat MVP recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-IO106-Ag | Mouse | Mouse MVP recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-IO106-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque MVP recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-IO106-Ag | Cat/Feline | Cat/Feline MVP recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-IO106-Ag | Dog/Canine | Dog/Canine MVP recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-IO106-Ag | Bovines/Cattle | Bovines/Cattle MVP recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-IO106-Ag | Equine/Horse | Equine/Horse MVP recombinant protein | Mammalian cell | Detail |
