Explore LGALS3BP gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
premier destination for multi-species gene research solutions
Target
sublocation: Secreted Protein/Potential Cytokines.
The galectins are a family of beta-galactoside-binding proteins implicated in modulating cell-cell and cell-matrix interactions. LGALS3BP has been found elevated in the serum of patients with cancer and in those infected by the human immunodeficiency virus (HIV). It appears to be implicated in immune response associated with natural killer (NK) and lymphokine-activated killer (LAK) cell cytotoxicity. Using fluorescence in situ hybridization the full length 90K cDNA has been localized to chromosome 17q25. The native protein binds specifically to a human macrophage-associated lectin known as Mac-2 and also binds galectin 1. [provided by RefSeq, Jul 2008]
| Target ID |
GM-IO086
|
| Target Name |
LGALS3BP
|
Gene Group ldentifer (Target Gene ID in Homo
species)
|
3959
|
| Gene ID |
100050573 (Equus caballus), 19039 (Mus musculus), 245955 (Rattus norvegicus), 3959 (Homo sapiens) 531137 (Bos taurus), 710853 (Macaca mulatta)
|
| Target Alternative Names |
90K,BTBD17B,Basement membrane autoantigen p105,CyCAP,Galectin-3-binding protein,LGALS3BP,Lectin galactoside-binding soluble 3-binding protein,Lgals3bp,M2BP,MAC-2-BP,MAC-2BP,MAC2BP,Mac-2 BP),Mac-2-binding protein (MAC2BP,Ppicap,TANGO10B,Tango10b,Tumor-associated antigen 90K,gp90,mama
|
| Uniprot Accession |
Q07797,O70513,Q08380,A7E3W2
|
| Protein Sub-location |
Secreted Protein/Potential Cytokines
|
| Category |
Therapeutics Target, Immuno-oncology Target
|
| Disease |
Ovary Cancer, Malignant neoplasm of bladder
|
| Gene Ensembl |
ENSECAG00000033385, ENSMUSG00000033880, ENSG00000108679, ENSBTAG00000001368, ENSMMUG00000019662
|
| Target Classification |
Checkpoint-Immuno Oncology
|
Pre-made viral vector of LGALS3BP cDNA Clones/ORF Plasmid
LGALS3BP siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo3959 | Pre-made Human LGALS3BP/90K/M2BP siRNA oligo Duplex | 3959 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo245955 | Pre-made Rat Lgals3bp/mama/CyCAP siRNA oligo Duplex | 245955 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo19039 | Pre-made Mouse Lgals3bp/90K/CyCAP siRNA oligo Duplex | 19039 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo710853 | Pre-made Cynomolgus/Rhesus macaque LGALS3BP siRNA oligo Duplex | 710853 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo531137 | Pre-made Bovines/Cattle LGALS3BP siRNA oligo Duplex | 531137 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100050573 | Pre-made Equine/Horse LGALS3BP siRNA oligo Duplex | 100050573 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
LGALS3BP antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-IO086-Ab | Human | Anti-Human LGALS3BP monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-rg-IO086-Ab | Rat | Anti-Rat LGALS3BP monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-mg-IO086-Ab | Mouse | Anti-Mouse LGALS3BP monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cynog-IO086-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque LGALS3BP monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-bovg-IO086-Ab | Bovines/Cattle | Anti-Bovines/Cattle LGALS3BP monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-equg-IO086-Ab | Equine/Horse | Anti-Equine/Horse LGALS3BP monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
LGALS3BP recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-IO086-Ag | Human | Human LGALS3BP recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-IO086-Ag | Rat | Rat LGALS3BP recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-IO086-Ag | Mouse | Mouse LGALS3BP recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-IO086-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque LGALS3BP recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-IO086-Ag | Bovines/Cattle | Bovines/Cattle LGALS3BP recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-IO086-Ag | Equine/Horse | Equine/Horse LGALS3BP recombinant protein | Mammalian cell | Detail |