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insights for Homo sapiens (human), Cynomolgus monkeys, rodents
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Target
sublocation: Transmembrane Protein.
Natural killer (NK) cells are lymphocytes that can mediate lysis of certain tumor cells and virus-infected cells without previous activation. They can also regulate specific humoral and cell-mediated immunity. The protein encoded by this gene belongs to the killer cell lectin-like receptor (KLR) family, which is a group of transmembrane proteins preferentially expressed in NK cells. Studies in mice suggested that the expression of this gene may be regulated by MHC class I molecules. [provided by RefSeq, Jun 2016]
| Target ID |
GM-IO082
|
| Target Name |
KLRG1
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
10219
|
| Gene ID |
100053516 (Equus caballus), 100295672 (Bos taurus), 101098640 (Felis catus), 10219 (Homo sapiens)
50928 (Mus musculus), 58975 (Rattus norvegicus), 611464 (Canis lupus familiaris), 716727 (Macaca mulatta)
|
| Target Alternative Names |
2F1,2F1-Ag,C-type lectin domain family 15 member A,CLEC15A,ITIM-containing receptor MAFA-L,KLRG1,Killer cell lectin-like receptor subfamily G member 1,Klrg1,MAFA,MAFA-2F1,MAFA-L,MAFA-LIKE,MAFA-like receptor,Mast cell function-associated antigen
|
| Uniprot Accession |
Q96E93,O88713,Q64335
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
Therapeutics Target, Immuno-oncology Target
|
| Gene Ensembl |
ENSECAG00000024523, ENSBTAG00000013640, ENSG00000139187, ENSMUSG00000030114, ENSCAFG00845028658, ENSMMUG00000001418
|
| Target Classification |
Checkpoint-Immuno Oncology
|
Pre-made viral vector of KLRG1 cDNA Clones/ORF Plasmid
KLRG1 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo10219 | Pre-made Human KLRG1/2F1/MAFA siRNA oligo Duplex | 10219 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo58975 | Pre-made Rat Klrg1/MAFA siRNA oligo Duplex | 58975 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo50928 | Pre-made Mouse Klrg1/MAFA/2F1-Ag siRNA oligo Duplex | 50928 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo716727 | Pre-made Cynomolgus/Rhesus macaque KLRG1 siRNA oligo Duplex | 716727 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101098640 | Pre-made Cat/Feline KLRG1 siRNA oligo Duplex | 101098640 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo611464 | Pre-made Dog/Canine KLRG1 siRNA oligo Duplex | 611464 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100295672 | Pre-made Bovines/Cattle KLRG1 siRNA oligo Duplex | 100295672 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100053516 | Pre-made Equine/Horse KLRG1 siRNA oligo Duplex | 100053516 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
KLRG1 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-IO082-Ab | Human | Anti-Human KLRG1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-rg-IO082-Ab | Rat | Anti-Rat KLRG1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-mg-IO082-Ab | Mouse | Anti-Mouse KLRG1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cynog-IO082-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque KLRG1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-felg-IO082-Ab | Cat/Feline | Anti-Cat/Feline KLRG1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cang-IO082-Ab | Dog/Canine | Anti-Dog/Canine KLRG1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-bovg-IO082-Ab | Bovines/Cattle | Anti-Bovines/Cattle KLRG1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-equg-IO082-Ab | Equine/Horse | Anti-Equine/Horse KLRG1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
KLRG1 VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-IO082-Ag | Human | Human KLRG1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-IO082-Ag | Rat | Rat KLRG1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-IO082-Ag | Mouse | Mouse KLRG1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-IO082-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque KLRG1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-IO082-Ag | Cat/Feline | Cat/Feline KLRG1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-IO082-Ag | Dog/Canine | Dog/Canine KLRG1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-IO082-Ag | Bovines/Cattle | Bovines/Cattle KLRG1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-IO082-Ag | Equine/Horse | Equine/Horse KLRG1 VLP (virus-like particle) | HEK293 | Products Developing |
