Explore Integrin Beta 5/Integrin beta-5/ITGB5 gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
premier destination for multi-species gene research solutions
Target
sublocation: Transmembrane Protein.
This gene encodes a beta subunit of integrin, which can combine with different alpha chains to form a variety of integrin heterodimers. Integrins are integral cell-surface receptors that participate in cell adhesion as well as cell-surface mediated signaling. The alphav beta5 integrin is involved in adhesion to vitronectin. [provided by RefSeq, Aug 2017]
| Target ID |
GM-IO079
|
| Target Name |
Integrin Beta 5/Integrin beta-5/ITGB5
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
3693
|
| Gene ID |
100070376 (Equus caballus), 101101247 (Felis catus), 16419 (Mus musculus), 257645 (Rattus norvegicus)
282564 (Bos taurus), 3693 (Homo sapiens), 608977 (Canis lupus familiaris), 715710 (Macaca mulatta)
|
| Target Alternative Names |
ITGB5,Itgb5,[b]5,[b]-5,[b]5A,[b]5B,beta5,ESTM23,beta-5,RGD1563276
|
| Uniprot Accession |
O70309,P80747,P18084
|
| Uniprot Entry Name |
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
Therapeutics Target, Immuno-oncology Target
|
| Disease |
|
| Disease from KEGG |
Phagosome, PI3K-Akt signaling pathway, Focal adhesion, ECM-receptor interaction, Regulation of actin cytoskeleton, Human papillomavirus infection, Proteoglycans in cancer, Hypertrophic cardiomyopathy, Arrhythmogenic right ventricular cardiomyopathy, Dilated cardiomyopathy
|
| Gene Ensembl |
ENSECAG00000007589, ENSMUSG00000022817, ENSBTAG00000013755, ENSG00000082781, ENSCAFG00845026987, ENSMMUG00000014516
|
| Target Classification |
Checkpoint-Immuno Oncology
|
Pre-made viral vector of Integrin Beta 5/Integrin beta-5/ITGB5 cDNA Clones/ORF Plasmid
Integrin Beta 5/Integrin beta-5/ITGB5 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo3693 | Pre-made Human ITGB5 siRNA oligo Duplex | 3693 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo257645 | Pre-made Rat Itgb5/RGD1563276 siRNA oligo Duplex | 257645 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo16419 | Pre-made Mouse Itgb5/[b]5/[b]-5 siRNA oligo Duplex | 16419 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo715710 | Pre-made Cynomolgus/Rhesus macaque ITGB5 siRNA oligo Duplex | 715710 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101101247 | Pre-made Cat/Feline ITGB5 siRNA oligo Duplex | 101101247 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo608977 | Pre-made Dog/Canine ITGB5 siRNA oligo Duplex | 608977 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo282564 | Pre-made Bovines/Cattle ITGB5 siRNA oligo Duplex | 282564 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100070376 | Pre-made Equine/Horse ITGB5 siRNA oligo Duplex | 100070376 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
Integrin Beta 5/Integrin beta-5/ITGB5 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-IO079-Ab | Human | Anti-Human Integrin Beta 5/Integrin beta-5/ITGB5 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-rg-IO079-Ab | Rat | Anti-Rat Integrin Beta 5/Integrin beta-5/ITGB5 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-mg-IO079-Ab | Mouse | Anti-Mouse Integrin Beta 5/Integrin beta-5/ITGB5 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cynog-IO079-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque Integrin Beta 5/Integrin beta-5/ITGB5 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-felg-IO079-Ab | Cat/Feline | Anti-Cat/Feline Integrin Beta 5/Integrin beta-5/ITGB5 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cang-IO079-Ab | Dog/Canine | Anti-Dog/Canine Integrin Beta 5/Integrin beta-5/ITGB5 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-bovg-IO079-Ab | Bovines/Cattle | Anti-Bovines/Cattle Integrin Beta 5/Integrin beta-5/ITGB5 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-equg-IO079-Ab | Equine/Horse | Anti-Equine/Horse Integrin Beta 5/Integrin beta-5/ITGB5 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
Integrin Beta 5/Integrin beta-5/ITGB5 VLP (virus-like particle)
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-IO079-Ag | Human | Human Integrin Beta 5/Integrin beta-5/ITGB5 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-IO079-Ag | Rat | Rat Integrin Beta 5/Integrin beta-5/ITGB5 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-IO079-Ag | Mouse | Mouse Integrin Beta 5/Integrin beta-5/ITGB5 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-IO079-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque Integrin Beta 5/Integrin beta-5/ITGB5 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-IO079-Ag | Cat/Feline | Cat/Feline Integrin Beta 5/Integrin beta-5/ITGB5 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-IO079-Ag | Dog/Canine | Dog/Canine Integrin Beta 5/Integrin beta-5/ITGB5 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-IO079-Ag | Bovines/Cattle | Bovines/Cattle Integrin Beta 5/Integrin beta-5/ITGB5 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-IO079-Ag | Equine/Horse | Equine/Horse Integrin Beta 5/Integrin beta-5/ITGB5 VLP (virus-like particle) | HEK293 | Products Developing |
