Explore IL27RA/IL27R gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
premier destination for multi-species gene research solutions
Target
sublocation: Transmembrane Protein.
In mice, CD4+ helper T-cells differentiate into type 1 (Th1) cells, which are critical for cell-mediated immunity, predominantly under the influence of IL12. Also, IL4 influences their differentiation into type 2 (Th2) cells, which are critical for most antibody responses. Mice deficient in these cytokines, their receptors, or associated transcription factors have impaired, but are not absent of, Th1 or Th2 immune responses. This gene encodes a protein which is similar to the mouse T-cell cytokine receptor Tccr at the amino acid level, and is predicted to be a glycosylated transmembrane protein. [provided by RefSeq, Jul 2008]
| Target ID |
GM-IO077
|
| Target Name |
IL27RA/IL27R
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
9466
|
| Gene ID |
101089988 (Felis catus), 102150342 (Equus caballus), 288905 (Rattus norvegicus), 484907 (Canis lupus familiaris)
50931 (Mus musculus), 514529 (Bos taurus), 717549 (Macaca mulatta), 9466 (Homo sapiens)
|
| Target Alternative Names |
CRL1,Cytokine receptor WSX-1,Cytokine receptor-like 1,IL-27 receptor subunit alpha,IL-27R,IL-27R subunit alpha,IL-27R-alpha,IL-27RA,IL27R,IL27RA,Il27ra,Interleukin-27 receptor subunit alpha,TCCR,Tccr,Type I T-cell cytokine receptor (TCCR),WSX-1,WSX1,Wsx1,ZcytoR1,zcytor1
|
| Uniprot Accession |
O70394,Q6UWB1
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
Therapeutics Target, Immuno-oncology Target, Cytokine Target
|
| Disease from KEGG |
Cytokine-cytokine receptor interaction, JAK-STAT signaling pathway, Th17 cell differentiation
|
| Gene Ensembl |
ENSECAG00000011964, ENSCAFG00845025289, ENSMUSG00000005465, ENSBTAG00000016933, ENSMMUG00000013538, ENSG00000104998
|
| Target Classification |
Cytokine Receptor, Checkpoint-Immuno Oncology
|
Pre-made viral vector of IL27RA/IL27R cDNA Clones/ORF Plasmid
IL27RA/IL27R siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo9466 | Pre-made Human IL27RA/CRL1/TCCR siRNA oligo Duplex | 9466 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo288905 | Pre-made Rat Il27ra siRNA oligo Duplex | 288905 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo50931 | Pre-made Mouse Il27ra/CRL1/Tccr siRNA oligo Duplex | 50931 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo717549 | Pre-made Cynomolgus/Rhesus macaque IL27RA siRNA oligo Duplex | 717549 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101089988 | Pre-made Cat/Feline IL27RA siRNA oligo Duplex | 101089988 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo484907 | Pre-made Dog/Canine IL27RA siRNA oligo Duplex | 484907 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo514529 | Pre-made Bovines/Cattle IL27RA siRNA oligo Duplex | 514529 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo102150342 | Pre-made Equine/Horse IL27RA siRNA oligo Duplex | 102150342 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
IL27RA/IL27R antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-IO077-Ab | Human | Anti-Human IL27RA/IL27R monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-rg-IO077-Ab | Rat | Anti-Rat IL27RA/IL27R monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-mg-IO077-Ab | Mouse | Anti-Mouse IL27RA/IL27R monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-cynog-IO077-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque IL27RA/IL27R monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-felg-IO077-Ab | Cat/Feline | Anti-Cat/Feline IL27RA/IL27R monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-cang-IO077-Ab | Dog/Canine | Anti-Dog/Canine IL27RA/IL27R monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-bovg-IO077-Ab | Bovines/Cattle | Anti-Bovines/Cattle IL27RA/IL27R monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-equg-IO077-Ab | Equine/Horse | Anti-Equine/Horse IL27RA/IL27R monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
IL27RA/IL27R VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-IO077-Ag | Human | Human IL27RA/IL27R VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-IO077-Ag | Rat | Rat IL27RA/IL27R VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-IO077-Ag | Mouse | Mouse IL27RA/IL27R VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-IO077-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque IL27RA/IL27R VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-IO077-Ag | Cat/Feline | Cat/Feline IL27RA/IL27R VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-IO077-Ag | Dog/Canine | Dog/Canine IL27RA/IL27R VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-IO077-Ag | Bovines/Cattle | Bovines/Cattle IL27RA/IL27R VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-IO077-Ag | Equine/Horse | Equine/Horse IL27RA/IL27R VLP (virus-like particle) | HEK293 | Products Developing |
