Explore IL-10RA/IL10RA/CD210/IL10R gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
premier destination for multi-species gene research solutions
Target
sublocation: Transmembrane Protein.
The protein encoded by this gene is a receptor for interleukin 10. This protein is structurally related to interferon receptors. It has been shown to mediate the immunosuppressive signal of interleukin 10, and thus inhibits the synthesis of proinflammatory cytokines. This receptor is reported to promote survival of progenitor myeloid cells through the insulin receptor substrate-2/PI 3-kinase/AKT pathway. Activation of this receptor leads to tyrosine phosphorylation of JAK1 and TYK2 kinases. Two transcript variants, one protein-coding and the other not protein-coding, have been found for this gene. [provided by RefSeq, Jan 2009]
| Target ID |
GM-IO069
|
| Target Name |
IL-10RA/IL10RA/CD210/IL10R
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
3587
|
| Gene ID |
100071172 (Equus caballus), 101087601 (Felis catus), 117539 (Rattus norvegicus), 16154 (Mus musculus)
3587 (Homo sapiens), 513478 (Bos taurus), 610823 (Canis lupus familiaris), 704383 (Macaca mulatta)
|
| Target Alternative Names |
CD210,CD210a,CDW210A,CDw210,CDw210a,HIL-10R,IL-10 receptor subunit alpha,IL-10R subunit alpha,IL-10R1,IL-10R1),IL-10RA,IL10R,IL10RA,Il10r,Il10ra,Interleukin-10 receptor subunit 1 (IL-10R subunit 1,Interleukin-10 receptor subunit alpha,mIL-10R
|
| Uniprot Accession |
Q61727,Q13651
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
Therapeutics Target, Immuno-oncology Target, Cytokine Target
|
| Disease from KEGG |
Cytokine-cytokine receptor interaction, Viral protein interaction with cytokine and cytokine receptor, JAK-STAT signaling pathway, Toxoplasmosis, Tuberculosis, Human cytomegalovirus infection
|
| Gene Ensembl |
ENSECAG00000015030, ENSMUSG00000032089, ENSG00000110324, ENSBTAG00000005215, ENSCAFG00845003194, ENSMMUG00000059436
|
| Target Classification |
Cytokine Receptor, Checkpoint-Immuno Oncology
|
Pre-made viral vector of IL-10RA/IL10RA/CD210/IL10R cDNA Clones/ORF Plasmid
IL-10RA/IL10RA/CD210/IL10R siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo3587 | Pre-made Human IL10RA/CD210/IL10R siRNA oligo Duplex | 3587 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo117539 | Pre-made Rat Il10ra siRNA oligo Duplex | 117539 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo16154 | Pre-made Mouse Il10ra/Il10r/CDw210 siRNA oligo Duplex | 16154 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo704383 | Pre-made Cynomolgus/Rhesus macaque IL10RA siRNA oligo Duplex | 704383 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101087601 | Pre-made Cat/Feline IL10RA siRNA oligo Duplex | 101087601 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo610823 | Pre-made Dog/Canine IL10RA siRNA oligo Duplex | 610823 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo513478 | Pre-made Bovines/Cattle IL10RA siRNA oligo Duplex | 513478 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100071172 | Pre-made Equine/Horse IL10RA siRNA oligo Duplex | 100071172 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
IL-10RA/IL10RA/CD210/IL10R antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-IO069-Ab | Human | Anti-Human IL-10RA/IL10RA/CD210/IL10R monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-rg-IO069-Ab | Rat | Anti-Rat IL-10RA/IL10RA/CD210/IL10R monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-mg-IO069-Ab | Mouse | Anti-Mouse IL-10RA/IL10RA/CD210/IL10R monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-cynog-IO069-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque IL-10RA/IL10RA/CD210/IL10R monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-felg-IO069-Ab | Cat/Feline | Anti-Cat/Feline IL-10RA/IL10RA/CD210/IL10R monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-cang-IO069-Ab | Dog/Canine | Anti-Dog/Canine IL-10RA/IL10RA/CD210/IL10R monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-bovg-IO069-Ab | Bovines/Cattle | Anti-Bovines/Cattle IL-10RA/IL10RA/CD210/IL10R monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-equg-IO069-Ab | Equine/Horse | Anti-Equine/Horse IL-10RA/IL10RA/CD210/IL10R monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
IL-10RA/IL10RA/CD210/IL10R VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-IO069-Ag | Human | Human IL-10RA/IL10RA/CD210/IL10R VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-IO069-Ag | Rat | Rat IL-10RA/IL10RA/CD210/IL10R VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-IO069-Ag | Mouse | Mouse IL-10RA/IL10RA/CD210/IL10R VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-IO069-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque IL-10RA/IL10RA/CD210/IL10R VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-IO069-Ag | Cat/Feline | Cat/Feline IL-10RA/IL10RA/CD210/IL10R VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-IO069-Ag | Dog/Canine | Dog/Canine IL-10RA/IL10RA/CD210/IL10R VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-IO069-Ag | Bovines/Cattle | Bovines/Cattle IL-10RA/IL10RA/CD210/IL10R VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-IO069-Ag | Equine/Horse | Equine/Horse IL-10RA/IL10RA/CD210/IL10R VLP (virus-like particle) | HEK293 | Products Developing |
