Explore HSPA4/HSP70 gene products and cross-species
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biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
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Target
sublocation: Introcelluar Protein.
Predicted to enable ATP binding activity. Involved in chaperone-mediated protein complex assembly and protein insertion into mitochondrial outer membrane. Located in cytosol and extracellular exosome. Implicated in Chagas disease. Biomarker of chronic obstructive pulmonary disease; rheumatoid arthritis; type 2 diabetes mellitus; and ulcerative colitis. [provided by Alliance of Genome Resources, Apr 2022]
| Target ID |
GM-IO062
|
| Target Name |
HSPA4/HSP70
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
3308
|
| Gene ID |
100072809 (Equus caballus), 101097784 (Felis catus), 15525 (Mus musculus), 266759 (Rattus norvegicus)
3308 (Homo sapiens), 474680 (Canis lupus familiaris), 536558 (Bos taurus), 709585 (Macaca mulatta)
|
| Target Alternative Names |
HSPA4,Hspa4,70kDa,APG-2,Hsp110,Hsp70RY,mKIAA4025,Hsp70,irp94,RY,HSPH2,hsp70,hsp70RY,HEL-S-5a,HS24/P52
|
| Uniprot Accession |
Q61316,O88600,P34932,Q2TFN9
|
| Uniprot Entry Name |
|
| Protein Sub-location |
Introcelluar Protein
|
| Category |
Therapeutics Target, Immuno-oncology Target
|
| Disease |
|
| Disease from KEGG |
Tight junction, Antigen processing and presentation, Lipid and atherosclerosis
|
| Gene Ensembl |
ENSECAG00000020813, ENSMUSG00000020361, ENSG00000170606, ENSCAFG00845011851, ENSBTAG00000015683, ENSMMUG00000009396
|
| Target Classification |
Checkpoint-Immuno Oncology
|
HSPA4/HSP70 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo3308 | Pre-made Human HSPA4/RY/APG-2 siRNA oligo Duplex | 3308 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo266759 | Pre-made Rat Hspa4/Hsp70/irp94 siRNA oligo Duplex | 266759 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo15525 | Pre-made Mouse Hspa4/70kDa/APG-2 siRNA oligo Duplex | 15525 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo709585 | Pre-made Cynomolgus/Rhesus macaque HSPA4 siRNA oligo Duplex | 709585 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101097784 | Pre-made Cat/Feline HSPA4 siRNA oligo Duplex | 101097784 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo474680 | Pre-made Dog/Canine HSPA4/APG-2 siRNA oligo Duplex | 474680 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo536558 | Pre-made Bovines/Cattle HSPA4 siRNA oligo Duplex | 536558 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100072809 | Pre-made Equine/Horse HSPA4 siRNA oligo Duplex | 100072809 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
HSPA4/HSP70 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-IO062-Ab | Human | Anti-Human HSPA4/HSP70 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-rg-IO062-Ab | Rat | Anti-Rat HSPA4/HSP70 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-mg-IO062-Ab | Mouse | Anti-Mouse HSPA4/HSP70 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cynog-IO062-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque HSPA4/HSP70 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-felg-IO062-Ab | Cat/Feline | Anti-Cat/Feline HSPA4/HSP70 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cang-IO062-Ab | Dog/Canine | Anti-Dog/Canine HSPA4/HSP70 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-bovg-IO062-Ab | Bovines/Cattle | Anti-Bovines/Cattle HSPA4/HSP70 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-equg-IO062-Ab | Equine/Horse | Anti-Equine/Horse HSPA4/HSP70 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
HSPA4/HSP70 recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-IO062-Ag | Human | Human HSPA4/HSP70 recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-IO062-Ag | Rat | Rat HSPA4/HSP70 recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-IO062-Ag | Mouse | Mouse HSPA4/HSP70 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-IO062-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque HSPA4/HSP70 recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-IO062-Ag | Cat/Feline | Cat/Feline HSPA4/HSP70 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-IO062-Ag | Dog/Canine | Dog/Canine HSPA4/HSP70 recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-IO062-Ag | Bovines/Cattle | Bovines/Cattle HSPA4/HSP70 recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-IO062-Ag | Equine/Horse | Equine/Horse HSPA4/HSP70 recombinant protein | Mammalian cell | Detail |
