Explore CNGB1/GARP gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
premier destination for multi-species gene research solutions
Target
sublocation: Transmembrane Protein.
In humans, the rod photoreceptor cGMP-gated cation channel helps regulate ion flow into the rod photoreceptor outer segment in response to light-induced alteration of the levels of intracellular cGMP. This channel consists of two subunits, alpha and beta, with the protein encoded by this gene representing the beta subunit. Defects in this gene are a cause of cause of retinitis pigmentosa type 45. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2013]
| Target ID |
GM-IO045
|
| Target Name |
CNGB1/GARP
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
1258
|
| Gene ID |
100062786 (Equus caballus), 101092568 (Felis catus), 102156683 (Canis lupus familiaris), 1258 (Homo sapiens)
281702 (Bos taurus), 333329 (Mus musculus), 706073 (Macaca mulatta), 83686 (Rattus norvegicus)
|
| Target Alternative Names |
CNCG2,CNCG3L,CNCG4,CNG channel beta-1,CNG-4,CNG4,CNG4),CNGB1,CNGB1B,Cngb1,Cngb1b,Cyclic nucleotide-gated cation channel 4 (CNG channel 4,Cyclic nucleotide-gated cation channel gamma,Cyclic nucleotide-gated cation channel modulatory subunit,Cyclic nucleotide-gated channel beta-1,GAR1,GARP,GARP2,Garp2,Glutamic acid-rich protein (GARP),Gm1959,RCNC2,RCNCb,RCNCbeta,RP45
|
| Uniprot Accession |
Q14028,Q28181,E1AZ71,A0A8I5ZN27
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
Therapeutics Target, Immuno-oncology Target
|
| Disease from KEGG |
cGMP-PKG signaling pathway, cAMP signaling pathway, Olfactory transduction
|
| Gene Ensembl |
ENSCAFG00845002559, ENSG00000070729, ENSBTAG00000005702, ENSMUSG00000031789, ENSMMUG00000022668
|
| Target Classification |
Checkpoint-Immuno Oncology
|
CNGB1/GARP siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo1258 | Pre-made Human CNGB1/CNG4/GAR1 siRNA oligo Duplex | 1258 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo83686 | Pre-made Rat Cngb1/CNG4/CNG-4 siRNA oligo Duplex | 83686 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo333329 | Pre-made Mouse Cngb1/CNG4/CNG-4 siRNA oligo Duplex | 333329 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo706073 | Pre-made Cynomolgus/Rhesus macaque CNGB1 siRNA oligo Duplex | 706073 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101092568 | Pre-made Cat/Feline CNGB1 siRNA oligo Duplex | 101092568 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo102156683 | Pre-made Dog/Canine CNGB1 siRNA oligo Duplex | 102156683 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo281702 | Pre-made Bovines/Cattle CNGB1/CNG4/GARP siRNA oligo Duplex | 281702 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100062786 | Pre-made Equine/Horse CNGB1 siRNA oligo Duplex | 100062786 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
CNGB1/GARP antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-IO045-Ab | Human | Anti-Human CNGB1/GARP monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-rg-IO045-Ab | Rat | Anti-Rat CNGB1/GARP monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-mg-IO045-Ab | Mouse | Anti-Mouse CNGB1/GARP monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cynog-IO045-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque CNGB1/GARP monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-felg-IO045-Ab | Cat/Feline | Anti-Cat/Feline CNGB1/GARP monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cang-IO045-Ab | Dog/Canine | Anti-Dog/Canine CNGB1/GARP monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-bovg-IO045-Ab | Bovines/Cattle | Anti-Bovines/Cattle CNGB1/GARP monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-equg-IO045-Ab | Equine/Horse | Anti-Equine/Horse CNGB1/GARP monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
CNGB1/GARP VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-IO045-Ag | Human | Human CNGB1/GARP VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-IO045-Ag | Rat | Rat CNGB1/GARP VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-IO045-Ag | Mouse | Mouse CNGB1/GARP VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-IO045-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque CNGB1/GARP VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-IO045-Ag | Cat/Feline | Cat/Feline CNGB1/GARP VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-IO045-Ag | Dog/Canine | Dog/Canine CNGB1/GARP VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-IO045-Ag | Bovines/Cattle | Bovines/Cattle CNGB1/GARP VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-IO045-Ag | Equine/Horse | Equine/Horse CNGB1/GARP VLP (virus-like particle) | HEK293 | Products Developing |
