Explore FLT3 Ligand/NeutraControl FLT3 Ligand/NeutraKine FLT3 Ligand/FLT3LG gene products and cross-species
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insights for Homo sapiens (human), Cynomolgus monkeys, rodents
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Target
sublocation: Transmembrane Protein.
Dendritic cells (DCs) provide the key link between innate and adaptive immunity by recognizing pathogens and priming pathogen-specific immune responses. FLT3LG controls the development of DCs and is particularly important for plasmacytoid DCs and CD8 (see MIM 186910)-positive classical DCs and their CD103 (ITGAE; MIM 604682)-positive tissue counterparts (summary by Sathaliyawala et al., 2010 [PubMed 20933441]).[supplied by OMIM, Jan 2011]
| Target ID |
GM-IO042
|
| Target Name |
FLT3 Ligand/NeutraControl FLT3 Ligand/NeutraKine FLT3 Ligand/FLT3LG
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
2323
|
| Gene ID |
100055522 (Equus caballus), 103691134 (Rattus norvegicus), 14256 (Mus musculus), 2323 (Homo sapiens)
282233 (Bos taurus), 442938 (Canis lupus familiaris), 493796 (Felis catus), 719239 (Macaca mulatta)
|
| Target Alternative Names |
FL,FLG3L,FLT3 Ligand,FLT3L,FLT3LG,Flt3 ligand,Flt3L,Flt3l,Flt3lg,Fms-related tyrosine kinase 3 ligand,Gm45713,IMD125,Ly72L,NeutraControl FLT3 Ligand,NeutraKine FLT3 Ligand,SL cytokine
|
| Uniprot Accession |
P49772,P49771
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
Therapeutics Target, Immuno-oncology Target
|
| Disease |
Breast Cancer
|
| Disease from KEGG |
MAPK signaling pathway, Ras signaling pathway, PI3K-Akt signaling pathway, Hematopoietic cell lineage, Pathways in cancer
|
| Gene Ensembl |
ENSECAG00000038488, ENSMUSG00000110206, ENSG00000090554, ENSBTAG00000038045, ENSCAFG00845024253
|
| Target Classification |
Checkpoint-Immuno Oncology
|
Pre-made viral vector of FLT3 Ligand/NeutraControl FLT3 Ligand/NeutraKine FLT3 Ligand/FLT3LG cDNA Clones/ORF Plasmid
FLT3 Ligand/NeutraControl FLT3 Ligand/NeutraKine FLT3 Ligand/FLT3LG siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo2323 | Pre-made Human FLT3LG/FL/FLG3L siRNA oligo Duplex | 2323 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo103691134 | Pre-made Rat Flt3lg/Gm45713 siRNA oligo Duplex | 103691134 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo14256 | Pre-made Mouse Flt3l/Ly72L/Flt3lg siRNA oligo Duplex | 14256 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo719239 | Pre-made Cynomolgus/Rhesus macaque FLT3LG/FLT3L siRNA oligo Duplex | 719239 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo493796 | Pre-made Cat/Feline FLT3LG siRNA oligo Duplex | 493796 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo442938 | Pre-made Dog/Canine FLT3LG siRNA oligo Duplex | 442938 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo282233 | Pre-made Bovines/Cattle FLT3LG siRNA oligo Duplex | 282233 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100055522 | Pre-made Equine/Horse FLT3LG siRNA oligo Duplex | 100055522 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
FLT3 Ligand/NeutraControl FLT3 Ligand/NeutraKine FLT3 Ligand/FLT3LG antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-IO042-Ab | Human | Anti-Human FLT3 Ligand/NeutraControl FLT3 Ligand/NeutraKine FLT3 Ligand/FLT3LG monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-rg-IO042-Ab | Rat | Anti-Rat FLT3 Ligand/NeutraControl FLT3 Ligand/NeutraKine FLT3 Ligand/FLT3LG monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-mg-IO042-Ab | Mouse | Anti-Mouse FLT3 Ligand/NeutraControl FLT3 Ligand/NeutraKine FLT3 Ligand/FLT3LG monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cynog-IO042-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque FLT3 Ligand/NeutraControl FLT3 Ligand/NeutraKine FLT3 Ligand/FLT3LG monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-felg-IO042-Ab | Cat/Feline | Anti-Cat/Feline FLT3 Ligand/NeutraControl FLT3 Ligand/NeutraKine FLT3 Ligand/FLT3LG monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cang-IO042-Ab | Dog/Canine | Anti-Dog/Canine FLT3 Ligand/NeutraControl FLT3 Ligand/NeutraKine FLT3 Ligand/FLT3LG monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-bovg-IO042-Ab | Bovines/Cattle | Anti-Bovines/Cattle FLT3 Ligand/NeutraControl FLT3 Ligand/NeutraKine FLT3 Ligand/FLT3LG monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-equg-IO042-Ab | Equine/Horse | Anti-Equine/Horse FLT3 Ligand/NeutraControl FLT3 Ligand/NeutraKine FLT3 Ligand/FLT3LG monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
FLT3 Ligand/NeutraControl FLT3 Ligand/NeutraKine FLT3 Ligand/FLT3LG VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-IO042-Ag | Human | Human FLT3 Ligand/NeutraControl FLT3 Ligand/NeutraKine FLT3 Ligand/FLT3LG VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-IO042-Ag | Rat | Rat FLT3 Ligand/NeutraControl FLT3 Ligand/NeutraKine FLT3 Ligand/FLT3LG VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-IO042-Ag | Mouse | Mouse FLT3 Ligand/NeutraControl FLT3 Ligand/NeutraKine FLT3 Ligand/FLT3LG VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-IO042-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque FLT3 Ligand/NeutraControl FLT3 Ligand/NeutraKine FLT3 Ligand/FLT3LG VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-IO042-Ag | Cat/Feline | Cat/Feline FLT3 Ligand/NeutraControl FLT3 Ligand/NeutraKine FLT3 Ligand/FLT3LG VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-IO042-Ag | Dog/Canine | Dog/Canine FLT3 Ligand/NeutraControl FLT3 Ligand/NeutraKine FLT3 Ligand/FLT3LG VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-IO042-Ag | Bovines/Cattle | Bovines/Cattle FLT3 Ligand/NeutraControl FLT3 Ligand/NeutraKine FLT3 Ligand/FLT3LG VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-IO042-Ag | Equine/Horse | Equine/Horse FLT3 Ligand/NeutraControl FLT3 Ligand/NeutraKine FLT3 Ligand/FLT3LG VLP (virus-like particle) | HEK293 | Products Developing |
