Explore Cadherin-17/CDH17 gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Transmembrane Protein.
This gene is a member of the cadherin superfamily, genes encoding calcium-dependent, membrane-associated glycoproteins. The encoded protein is cadherin-like, consisting of an extracellular region, containing 7 cadherin domains, and a transmembrane region but lacking the conserved cytoplasmic domain. The protein is a component of the gastrointestinal tract and pancreatic ducts, acting as an intestinal proton-dependent peptide transporter in the first step in oral absorption of many medically important peptide-based drugs. The protein may also play a role in the morphological organization of liver and intestine. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2009]
| Target ID |
GM-IO023
|
| Target Name |
Cadherin-17/CDH17
|
Gene Group ldentifer (Target Gene ID in Homo
species)
|
1015
|
| Gene ID |
100051232 (Equus caballus), 101083236 (Felis catus), 1015 (Homo sapiens), 117048 (Rattus norvegicus) 12557 (Mus musculus), 487050 (Canis lupus familiaris), 507526 (Bos taurus), 698886 (Macaca mulatta)
|
| Target Alternative Names |
CDH16,CDH17,Cadherin-17,Cdh17,HPT-1,HPT-1/LI,HPT1,Intestinal peptide-associated transporter HPT-1,Liver-intestine cadherin (LI-cadherin)
|
| Uniprot Accession |
Q12864,P55281,Q9R100
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
Therapeutics Target, Immuno-oncology Target
|
| Disease |
cancer
|
| Disease from KEGG |
Gastric cancer
|
| Gene Ensembl |
ENSECAG00000017615, ENSG00000079112, ENSMUSG00000028217, ENSCAFG00845014632, ENSBTAG00000021964, ENSMMUG00000020010
|
| Target Classification |
Checkpoint-Immuno Oncology
|
Cadherin-17/CDH17 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo1015 | Pre-made Human CDH17/HPT1/CDH16 siRNA oligo Duplex | 1015 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo117048 | Pre-made Rat Cdh17 siRNA oligo Duplex | 117048 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo12557 | Pre-made Mouse Cdh17/HPT-1/HPT-1/LI siRNA oligo Duplex | 12557 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo698886 | Pre-made Cynomolgus/Rhesus macaque CDH17 siRNA oligo Duplex | 698886 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101083236 | Pre-made Cat/Feline CDH17 siRNA oligo Duplex | 101083236 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo487050 | Pre-made Dog/Canine CDH17 siRNA oligo Duplex | 487050 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo507526 | Pre-made Bovines/Cattle CDH17 siRNA oligo Duplex | 507526 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100051232 | Pre-made Equine/Horse CDH17 siRNA oligo Duplex | 100051232 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
Cadherin-17/CDH17 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-IO023-Ab | Human | Anti-Human Cadherin-17/CDH17 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-rg-IO023-Ab | Rat | Anti-Rat Cadherin-17/CDH17 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-mg-IO023-Ab | Mouse | Anti-Mouse Cadherin-17/CDH17 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cynog-IO023-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque Cadherin-17/CDH17 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-felg-IO023-Ab | Cat/Feline | Anti-Cat/Feline Cadherin-17/CDH17 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cang-IO023-Ab | Dog/Canine | Anti-Dog/Canine Cadherin-17/CDH17 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-bovg-IO023-Ab | Bovines/Cattle | Anti-Bovines/Cattle Cadherin-17/CDH17 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-equg-IO023-Ab | Equine/Horse | Anti-Equine/Horse Cadherin-17/CDH17 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
Cadherin-17/CDH17 VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-IO023-Ag | Human | Human Cadherin-17/CDH17 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-IO023-Ag | Rat | Rat Cadherin-17/CDH17 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-IO023-Ag | Mouse | Mouse Cadherin-17/CDH17 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-IO023-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque Cadherin-17/CDH17 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-IO023-Ag | Cat/Feline | Cat/Feline Cadherin-17/CDH17 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-IO023-Ag | Dog/Canine | Dog/Canine Cadherin-17/CDH17 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-IO023-Ag | Bovines/Cattle | Bovines/Cattle Cadherin-17/CDH17 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-IO023-Ag | Equine/Horse | Equine/Horse Cadherin-17/CDH17 VLP (virus-like particle) | HEK293 | Products Developing |