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Target
sublocation: Transmembrane Protein.
This gene encodes a receptor for the OX-2 membrane glycoprotein. Both the receptor and substrate are cell surface glycoproteins containing two immunoglobulin-like domains. This receptor is restricted to the surfaces of myeloid lineage cells and the receptor-substrate interaction may function as a myeloid downregulatory signal. Mouse studies of a related gene suggest that this interaction may control myeloid function in a tissue-specific manner. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Jul 2008]
| Target ID |
GM-IO018
|
| Target Name |
CD200R1
|
Gene Group ldentifer (Target Gene ID in Homo
species)
|
131450
|
| Gene ID |
100071456 (Equus caballus), 131450 (Homo sapiens), 57781 (Mus musculus), 708734 (Macaca mulatta)
|
| Target Alternative Names |
CD200 cell surface glycoprotein receptor,CD200R,CD200R1,Cd200r1,Cell surface glycoprotein CD200 receptor 1,Cell surface glycoprotein OX2 receptor 1,HCRTR2,MOX2R,Mox2r,OX2R
|
| Uniprot Accession |
Q8TD46,Q9ES57
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
Therapeutics Target, Immuno-oncology Target
|
| Disease from KEGG |
Kaposi sarcoma-associated herpesvirus infection
|
| Gene Ensembl |
ENSECAG00000015753, ENSG00000163606, ENSMUSG00000022667, ENSMMUG00000003199
|
| Target Classification |
Checkpoint-Immuno Oncology
|
Pre-made viral vector of CD200R1 cDNA Clones/ORF Plasmid
CD200R1 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo131450 | Pre-made Human CD200R1/OX2R/MOX2R siRNA oligo Duplex | 131450 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo57781 | Pre-made Mouse Cd200r1/OX2R/Mox2r siRNA oligo Duplex | 57781 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo708734 | Pre-made Cynomolgus/Rhesus macaque CD200R1 siRNA oligo Duplex | 708734 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100071456 | Pre-made Equine/Horse CD200R1 siRNA oligo Duplex | 100071456 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
CD200R1 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-IO018-Ab | Human | Anti-Human CD200R1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-mg-IO018-Ab | Mouse | Anti-Mouse CD200R1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cynog-IO018-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque CD200R1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-equg-IO018-Ab | Equine/Horse | Anti-Equine/Horse CD200R1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
CD200R1 VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-IO018-Ag | Human | Human CD200R1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-IO018-Ag | Mouse | Mouse CD200R1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-IO018-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque CD200R1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-IO018-Ag | Equine/Horse | Equine/Horse CD200R1 VLP (virus-like particle) | HEK293 | Products Developing |