Explore CD155/PVR gene products and cross-species
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biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Transmembrane Protein.
The protein encoded by this gene is a transmembrane glycoprotein belonging to the immunoglobulin superfamily. The external domain mediates cell attachment to the extracellular matrix molecule vitronectin, while its intracellular domain interacts with the dynein light chain Tctex-1/DYNLT1. The gene is specific to the primate lineage, and serves as a cellular receptor for poliovirus in the first step of poliovirus replication. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2008]
| Target ID |
GM-IO017
|
| Target Name |
CD155/PVR
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
5817
|
| Gene ID |
101096773 (Felis catus), 25066 (Rattus norvegicus), 476439 (Canis lupus familiaris), 526865 (Bos taurus)
5817 (Homo sapiens)
|
| Target Alternative Names |
CD155,HVED,NECL5,Necl-5,Nectin-like protein 5 (NECL-5),PVR,PVS,Poliovirus receptor,Pvr,TAGE4,Taa1,Tage4
|
| Uniprot Accession |
P15151
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
Therapeutics Target, Immuno-oncology Target
|
| Disease |
Malignant neoplasm of bladder
|
| Disease from KEGG |
Cell adhesion molecules
|
| Gene Ensembl |
ENSCAFG00845007353, ENSBTAG00000048075, ENSG00000073008
|
| Target Classification |
Checkpoint-Immuno Oncology
|
Pre-made viral vector of CD155/PVR cDNA Clones/ORF Plasmid
CD155/PVR siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo5817 | Pre-made Human PVR/PVS/HVED siRNA oligo Duplex | 5817 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo25066 | Pre-made Rat Pvr/Taa1/Tage4 siRNA oligo Duplex | 25066 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101096773 | Pre-made Cat/Feline PVR siRNA oligo Duplex | 101096773 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo476439 | Pre-made Dog/Canine PVR siRNA oligo Duplex | 476439 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo526865 | Pre-made Bovines/Cattle PVR siRNA oligo Duplex | 526865 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
CD155/PVR antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-IO017-Ab | Human | Anti-Human CD155/PVR monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-rg-IO017-Ab | Rat | Anti-Rat CD155/PVR monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-felg-IO017-Ab | Cat/Feline | Anti-Cat/Feline CD155/PVR monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cang-IO017-Ab | Dog/Canine | Anti-Dog/Canine CD155/PVR monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-bovg-IO017-Ab | Bovines/Cattle | Anti-Bovines/Cattle CD155/PVR monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
CD155/PVR VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-IO017-Ag | Human | Human CD155/PVR VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-IO017-Ag | Rat | Rat CD155/PVR VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-IO017-Ag | Cat/Feline | Cat/Feline CD155/PVR VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-IO017-Ag | Dog/Canine | Dog/Canine CD155/PVR VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-IO017-Ag | Bovines/Cattle | Bovines/Cattle CD155/PVR VLP (virus-like particle) | HEK293 | Products Developing |
