Explore B7-H6/NCR3LG1 gene products and cross-species
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Target
sublocation: Transmembrane Protein.
B7H6 belongs to the B7 family (see MIM 605402) and is selectively expressed on tumor cells. Interaction of B7H6 with NKp30 (NCR3; MIM 611550) results in natural killer (NK) cell activation and cytotoxicity (Brandt et al., 2009 [PubMed 19528259]).[supplied by OMIM, Jan 2011]
| Target ID |
GM-IO012
|
| Target Name |
B7-H6/NCR3LG1
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
374383
|
| Gene ID |
100071780 (Equus caballus), 101095854 (Felis catus), 102154898 (Canis lupus familiaris), 374383 (Homo sapiens)
523303 (Bos taurus), 691092 (Rattus norvegicus), 696844 (Macaca mulatta)
|
| Target Alternative Names |
B7 homolog 6 (B7-H6),B7-H6,B7H6,DKFZp686O24166,NCR3LG1,Natural cytotoxicity triggering receptor 3 ligand 1,Ncr3lg1
|
| Uniprot Accession |
Q68D85
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
Therapeutics Target, Immuno-oncology Target
|
| Gene Ensembl |
ENSCAFG00845014205, ENSG00000188211, ENSBTAG00000050060
|
| Target Classification |
Checkpoint-Immuno Oncology
|
Pre-made viral vector of B7-H6/NCR3LG1 cDNA Clones/ORF Plasmid
B7-H6/NCR3LG1 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo374383 | Pre-made Human NCR3LG1/B7H6/B7-H6 siRNA oligo Duplex | 374383 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo691092 | Pre-made Rat Ncr3lg1/B7H6 siRNA oligo Duplex | 691092 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo696844 | Pre-made Cynomolgus/Rhesus macaque NCR3LG1 siRNA oligo Duplex | 696844 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101095854 | Pre-made Cat/Feline NCR3LG1 siRNA oligo Duplex | 101095854 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo102154898 | Pre-made Dog/Canine NCR3LG1 siRNA oligo Duplex | 102154898 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo523303 | Pre-made Bovines/Cattle NCR3LG1/B7H6 siRNA oligo Duplex | 523303 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100071780 | Pre-made Equine/Horse NCR3LG1 siRNA oligo Duplex | 100071780 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
B7-H6/NCR3LG1 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-IO012-Ab | Human | Anti-Human B7-H6/NCR3LG1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-rg-IO012-Ab | Rat | Anti-Rat B7-H6/NCR3LG1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cynog-IO012-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque B7-H6/NCR3LG1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-felg-IO012-Ab | Cat/Feline | Anti-Cat/Feline B7-H6/NCR3LG1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cang-IO012-Ab | Dog/Canine | Anti-Dog/Canine B7-H6/NCR3LG1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-bovg-IO012-Ab | Bovines/Cattle | Anti-Bovines/Cattle B7-H6/NCR3LG1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-equg-IO012-Ab | Equine/Horse | Anti-Equine/Horse B7-H6/NCR3LG1 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
B7-H6/NCR3LG1 VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-IO012-Ag | Human | Human B7-H6/NCR3LG1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-IO012-Ag | Rat | Rat B7-H6/NCR3LG1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-IO012-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque B7-H6/NCR3LG1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-IO012-Ag | Cat/Feline | Cat/Feline B7-H6/NCR3LG1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-IO012-Ag | Dog/Canine | Dog/Canine B7-H6/NCR3LG1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-IO012-Ag | Bovines/Cattle | Bovines/Cattle B7-H6/NCR3LG1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-IO012-Ag | Equine/Horse | Equine/Horse B7-H6/NCR3LG1 VLP (virus-like particle) | HEK293 | Products Developing |
